Genotoxicity of Retroviral Integration In Hematopoietic Cells von Nienhuis, Arthur W, Dunbar, Cynthia E, Sorrentino, Brian P

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Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier von Yasuda, Kazuto, Cline, Cynthia, Vogel, Peter, Onciu, Mihaela, Fatima, Soghra, Sorrentino, Brian P, Thirumaran, Ranjit K, Ekins, Sean, Urade, Yoshihiro, Fujimori, Ko, Schuetz, Erin G

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Clinical strategies for expansion of haematopoietic stem cells von Sorrentino, Brian P

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The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme von Krishnamurthy, Partha, Ross, Douglas D, Nakanishi, Takeo, Bailey-Dell, Kim, Zhou, Sheng, Mercer, Kelly E, Sarkadi, Balazs, Sorrentino, Brian P, Schuetz, John D

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Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells von Cicero, Samantha A, Johnson, Dianna, Reyntjens, Steve, Frase, Sharon, Connell, Samuel, Chow, Lionel M.L, Baker, Suzanne J, Sorrentino, Brian P, Dyer, Michael A

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Abcg2 Expression Marks Tissue-Specific Stem Cells in Multiple Organs in a Mouse Progeny Tracking Model von Fatima, Soghra, Zhou, Sheng, Sorrentino, Brian P.

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype von Sorrentino, Brian P, Zhou, Sheng, Schuetz, John D, Bunting, Kevin D, Colapietro, Anne-Marie, Sampath, Janardhan, Morris, John J, Lagutina, Irina, Grosveld, Gerard C, Osawa, Mitsujiro, Nakauchi, Hiromitsu

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Bcrp1 Gene Expression Is Required for Normal Numbers of Side Population Stem Cells in Mice, and Confers Relative Protection to Mitoxantrone in Hematopoietic Cells in vivo von Zhou, Sheng, Morris, John J., Barnes, Yuxiao, Lan, Lubin, Schuetz, John D., Sorrentino, Brian P.

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Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection von Throm, Robert E., Ouma, Annastasia A., Zhou, Sheng, Chandrasekaran, Anantharaman, Lockey, Timothy, Greene, Michael, De Ravin, Suk See, Moayeri, Morvarid, Malech, Harry L., Sorrentino, Brian P., Gray, John T.

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ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy von Morfouace, Marie, Cheepala, Satish, Jackson, Sadhana, Fukuda, Yu, Patel, Yogesh T, Fatima, Soghra, Kawauchi, Daisuke, Shelat, Anang A, Stewart, Clinton F, Sorrentino, Brian P, Schuetz, John D, Roussel, Martine F

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Unique Risk Factors for Insertional Mutagenesis in a Mouse Model of XSCID Gene Therapy von Shou, Yan, Ma, Zhijun, Lu, Taihe, Sorrentino, Brian P.

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Mouse transplant models for evaluating the oncogenic risk of a self-inactivating XSCID lentiviral vector von Zhou, Sheng, Ma, Zhijun, Lu, Taihe, Janke, Laura, Gray, John T, Sorrentino, Brian P

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Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo von Yu, Hui, Neale, Geoffrey, Zhang, Hui, Lee, Han M., Ma, Zhijun, Zhou, Sheng, Forget, Bernard G., Sorrentino, Brian P.

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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia von Liu, Yu, Easton, John, Shao, Ying, Maciaszek, Jamie, Wang, Zhaoming, Wilkinson, Mark R, McCastlain, Kelly, Edmonson, Michael, Pounds, Stanley B, Shi, Lei, Zhou, Xin, Ma, Xiaotu, Sioson, Edgar, Li, Yongjin, Rusch, Michael, Gupta, Pankaj, Pei, Deqing, Cheng, Cheng, Smith, Malcolm A, Auvil, Jaime Guidry, Gerhard, Daniela S, Relling, Mary V, Winick, Naomi J, Carroll, Andrew J, Heerema, Nyla A, Raetz, Elizabeth, Devidas, Meenakshi, Willman, Cheryl L, Harvey, Richard C, Carroll, William L, Dunsmore, Kimberly P, Winter, Stuart S, Wood, Brent L, Sorrentino, Brian P, Downing, James R, Loh, Mignon L, Hunger, Stephen P, Zhang, Jinghui, Mullighan, Charles G

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Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels von Zhou, Sheng, Zong, Yang, Ney, Paul A., Nair, Geeta, Stewart, Clinton F., Sorrentino, Brian P.

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3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates von Bonner, Melissa A., Morales-Hernández, Antonio, Zhou, Sheng, Ma, Zhijun, Condori, Jose, Wang, Yong-Dong, Fatima, Soghra, Palmer, Lance E., Janke, Laura J., Fowler, Stephanie, Sorrentino, Brian P., McKinney-Freeman, Shannon

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Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1 von Mamcarz, Ewelina, Zhou, Sheng, Lockey, Timothy, Abdelsamed, Hossam, Cross, Shane J, Kang, Guolian, Ma, Zhijun, Condori, Jose, Dowdy, Jola, Triplett, Brandon, Li, Chen, Maron, Gabriela, Aldave Becerra, Juan C, Church, Joseph A, Dokmeci, Elif, Love, James T, da Matta Ain, Ana C, van der Watt, Hedi, Tang, Xing, Janssen, William, Ryu, Byoung Y, De Ravin, Suk See, Weiss, Mitchell J, Youngblood, Benjamin, Long-Boyle, Janel R, Gottschalk, Stephen, Meagher, Michael M, Malech, Harry L, Puck, Jennifer M, Cowan, Morton J, Sorrentino, Brian P

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Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis von Fukuda, Yu, Wang, Yao, Lian, Shangli, Lynch, John, Nagai, Shinjiro, Fanshawe, Bruce, Kandilci, Ayten, Janke, Laura J, Neale, Geoffrey, Fan, Yiping, Sorrentino, Brian P, Roussel, Martine F, Grosveld, Gerard, Schuetz, John D

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Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells von Jiang, Jie, Yu, Hui, Shou, Yan, Neale, Geoffrey, Zhou, Sheng, Lu, Taihe, Sorrentino, Brian P.

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Marking of definitive HSC precursors in E7.5–E8.5 embryos using an Abcg2-CreER lineage-tracing mouse model von Fatima, Soghra, Zhou, Sheng, Sorrentino, Brian P.

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