Alzheimerʼs PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide von Guo, Qing, Furukawa, Katsutoshi, Sopher, Bryce L, Pham, Dao G, Xie, Jun, Robinson, Nic, Martin, George M, Mattson, Mark P

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Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid β-peptide toxicity : Central roles of superoxide production and caspase activation von QING GUO, SEBASTIAN, L, SOPHER, B. L, MILLER, M. W, WARE, C. B, MARTIN, G. M, MATTSON, M. P

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Increased Activity‐Regulating and Neuroprotective Efficacy of α‐Secretase‐Derived Secreted Amyloid Precursor Protein Conferred by a C‐Terminal Heparin‐Binding Domain von Furukawa, Katsutoshi, Sopher, Bryce L., Rydel, Russell E., Begley, James G., Pham, Dao G., Martin, George M., Fox, Michael, Mattson, Mark P.

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Androgen Receptor YAC Transgenic Mice Recapitulate SBMA Motor Neuronopathy and Implicate VEGF164 in the Motor Neuron Degeneration von Sopher, Bryce L, Thomas, Patrick S, LaFevre-Bernt, Michelle A, Holm, Ida E, Wilke, Scott A, Ware, Carol B, Jin, Lee-Way, Libby, Randell T, Ellerby, Lisa M, La Spada, Albert R

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice von Guo, Qing, Fu, Weiming, Sopher, Bryce L., Miller, Miles W., Ware, Carol B., Martin, George M., Mattson, Mark P.

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Polyglutamine-Expanded Ataxin-7 Antagonizes CRX Function and Induces Cone-Rod Dystrophy in a Mouse Model of SCA7 von La Spada, Albert R., Fu, Ying-Hui, Sopher, Bryce L., Libby, Randell T., Wang, Xuejiao, Li, Lili Y., Einum, David D., Huang, Jing, Possin, Daniel E., Smith, Annette C., Martinez, Refugio A., Koszdin, Kari L., Treuting, Piper M., Ware, Carol B., Hurley, James B., Ptáček, Louis J., Chen, Shiming

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Alzheimer's Presenilin Mutation Sensitizes Neural Cells to Apoptosis Induced by Trophic Factor Withdrawal and Amyloid beta -Peptide: Involvement of Calcium and Oxyradicals von Guo, Qing, Sopher, Bryce L, Furukawa, Katsutoshi, Pham, Dao G, Robinson, Nic, Martin, George M, Mattson, Mark P

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cDNA Cloning and Chromosome Mapping of the Human Fe65 Gene: Interaction of the Conserved Cytoplasmic Domains of the Human β-amyloid Precursor Protein and Its Homologues with the Mo... von Brassler, Steven L., Gray, Matthew D., Sopher, Bryce L., Hu, Qubai, Hearn, Mark G., Pham, Dao G., Dinulos, Mary Beth, Fukuchi, Ken-Ichiro, Sisodia, Sangram S., Miller, Margaret A., Disteche, Christine M., Martin, George M.

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The Werner syndrome protein is a DNA helicase von Gray, Matthew D., Shen, Jiang-Cheng, Kamath-Loeb, Ashwini S., Blank, A., Sopher, Bryce L., Martin, George M., Oshima, Junko, Loeb, Lawrence A.

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Efficient recombination-based methods for bacterial artificial chromosome fusion and mutagenesis von Sopher, Bryce L., La Spada, Albert R.

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Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localizatio... von Chen, Shiming, Peng, Guang-Hua, Wang, Xuejiao, Smith, Annette C., Grote, Sara K., Sopher, Bryce L., La Spada, Albert R.

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Neurotrophic Factors [Activity-Dependent Neurotrophic Factor (ADNF) and Basic Fibroblast Growth Factor (bFGF)] Interrupt Excitotoxic Neurodegenerative Cascades Promoted by a PS1 Mu... von Guo, Qing, Sebastian, Lois, Sopher, Bryce L., Miller, Miles W., Glazner, Gordon W., Ware, Carol B., Martin, George M., Mattson, Mark P.

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Pescadillo, a Novel Cell Cycle Regulatory Protein Abnormally Expressed in Malignant Cells von Kinoshita, Yoshito, Jarell, Abel D., Flaman, Jean Michel, Foltz, Greg, Schuster, James, Sopher, Bryce L., Irvin, Dwain K., Kanning, Kevin, Kornblum, Harley I., Nelson, Peter S., Hieter, Phil, Morrison, Richard S.

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Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction von Guyenet, Stephan J, Mookerjee, Shona S, Lin, Amy, Custer, Sara K, Chen, Sylvia F, Sopher, Bryce L, La Spada, Albert R, Ellerby, Lisa M

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Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7 von Furrer, Stephanie A, Waldherr, Sarah M, Mohanachandran, Mathini S, Baughn, Travis D, Nguyen, Kien-Thiet, Sopher, Bryce L, Damian, Vincent A, Garden, Gwenn A, La Spada, Albert R

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Bovine kidney β-mannosidase : purification and characterization von SOPHER, B. L, TRAVISS, C. E, CAVANAGH, K. T, JONES, M. Z, FRIDERICI, K. H

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Purification and characterization of goat lysosomal beta-mannosidase using monoclonal and polyclonal antibodies von Sopher, B.L. (Michigan State University, East Lansing, MI), Traviss, C.E, Cavanagh, K.T, Jones, M.Z, Friderici, K.H

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In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis von Sopher, Bryce L, Myrick, Scott B, Hong, Julie Y, Smith, Annette C, La Spada, Albert R

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Polyglutamine-Expanded Ataxin-7 Promotes Non-Cell-Autonomous Purkinje Cell Degeneration and Displays Proteolytic Cleavage in Ataxic Transgenic Mice von Garden, Gwenn A, Libby, Randell T, Fu, Ying-Hui, Kinoshita, Yoshito, Huang, Jing, Possin, Daniel E, Smith, Annette C, Martinez, Refugio A, Fine, Gabriel C, Grote, Sara K, Ware, Carol B, Einum, David D, Morrison, Richard S, Ptacek, Louis J, Sopher, Bryce L, Spada, Albert R. La

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Molecular cloning and characterization of bovine beta-mannosidase von Chen, H. (Michigan State University, East Lansing, MI.), Leipprandt, J.R, Traviss, C.E, Sopher, B.L, Jones, M.Z, Cavanagh, K.T, Friderici, K.H

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