Origins and Mechanisms of miRNAs and siRNAs von Carthew, Richard W., Sontheimer, Erik J.

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CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA von Marraffini, Luciano A, Sontheimer, Erik J

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Naturally Occurring Off-Switches for CRISPR-Cas9 von Pawluk, April, Amrani, Nadia, Zhang, Yan, Garcia, Bianca, Hidalgo-Reyes, Yurima, Lee, Jooyoung, Edraki, Alireza, Shah, Megha, Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.

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Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis von Zhang, Yan, Heidrich, Nadja, Ampattu, Biju Joseph, Gunderson, Carl W., Seifert, H. Steven, Schoen, Christoph, Vogel, Jörg, Sontheimer, Erik J.

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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis von Hou, Zhonggang, Zhang, Yan, Propson, Nicholas E., Howden, Sara E., Chu, Li-Fang, Sontheimer, Erik J., Thomson, James A.

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice von Liu, Pengpeng, Liang, Shun-Qing, Zheng, Chunwei, Mintzer, Esther, Zhao, Yan G., Ponnienselvan, Karthikeyan, Mir, Aamir, Sontheimer, Erik J., Gao, Guangping, Flotte, Terence R., Wolfe, Scot A., Xue, Wen

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Assembly and function of RNA silencing complexes von Sontheimer, Erik J

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Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses von Wang, Dan, Mou, Haiwei, Li, Shaoyong, Li, Yingxiang, Hough, Soren, Tran, Karen, Li, Jia, Yin, Hao, Anderson, Daniel G, Sontheimer, Erik J, Weng, Zhiping, Gao, Guangping, Xue, Wen

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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo von Ibraheim, Raed, Song, Chun-Qing, Mir, Aamir, Amrani, Nadia, Xue, Wen, Sontheimer, Erik J

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Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins von Lee, Jooyoung, Mou, Haiwei, Ibraheim, Raed, Liang, Shun-Qing, Liu, Pengpeng, Xue, Wen, Sontheimer, Erik J

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A Cas9 with PAM recognition for adenine dinucleotides von Chatterjee, Pranam, Lee, Jooyoung, Nip, Lisa, Koseki, Sabrina R. T., Tysinger, Emma, Sontheimer, Erik J., Jacobson, Joseph M., Jakimo, Noah

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DNase H Activity of Neisseria meningitidis Cas9 von Zhang, Yan, Rajan, Rakhi, Seifert, H. Steven, Mondragón, Alfonso, Sontheimer, Erik J.

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Template-jumping prime editing enables large insertion and exon rewriting in vivo von Zheng, Chunwei, Liu, Bin, Dong, Xiaolong, Gaston, Nicholas, Sontheimer, Erik J., Xue, Wen

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Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing von Mir, Aamir, Alterman, Julia F., Hassler, Matthew R., Debacker, Alexandre J., Hudgens, Edward, Echeverria, Dimas, Brodsky, Michael H., Khvorova, Anastasia, Watts, Jonathan K., Sontheimer, Erik J.

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Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo von Ibraheim, Raed, Tai, Phillip W. L., Mir, Aamir, Javeed, Nida, Wang, Jiaming, Rodríguez, Tomás C., Namkung, Suk, Nelson, Samantha, Khokhar, Eraj Shafiq, Mintzer, Esther, Maitland, Stacy, Chen, Zexiang, Cao, Yueying, Tsagkaraki, Emmanouela, Wolfe, Scot A., Wang, Dan, Pai, Athma A., Xue, Wen, Gao, Guangping, Sontheimer, Erik J.

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CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease von Tsagkaraki, Emmanouela, Nicoloro, Sarah M., DeSouza, Tiffany, Solivan-Rivera, Javier, Desai, Anand, Lifshitz, Lawrence M., Shen, Yuefei, Kelly, Mark, Guilherme, Adilson, Henriques, Felipe, Amrani, Nadia, Ibraheim, Raed, Rodriguez, Tomas C., Luk, Kevin, Maitland, Stacy, Friedline, Randall H., Tauer, Lauren, Hu, Xiaodi, Kim, Jason K., Wolfe, Scot A., Sontheimer, Erik J., Corvera, Silvia, Czech, Michael P.

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NmeCas9 is an intrinsically high-fidelity genome-editing platform von Amrani, Nadia, Gao, Xin D, Liu, Pengpeng, Edraki, Alireza, Mir, Aamir, Ibraheim, Raed, Gupta, Ankit, Sasaki, Kanae E, Wu, Tong, Donohoue, Paul D, Settle, Alexander H, Lied, Alexandra M, McGovern, Kyle, Fuller, Chris K, Cameron, Peter, Fazzio, Thomas G, Zhu, Lihua Julie, Wolfe, Scot A, Sontheimer, Erik J

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Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts von Shin, Minwook, Chan, Io Long, Cao, Yuming, Gruntman, Alisha M, Lee, Jonathan, Sousa, Jacquelyn, Rodríguez, Tomás C, Echeverria, Dimas, Devi, Gitali, Debacker, Alexandre J, Moazami, Michael P, Krishnamurthy, Pranathi Meda, Rembetsy-Brown, Julia M, Kelly, Karen, Yukselen, Onur, Donnard, Elisa, Parsons, Teagan J, Khvorova, Anastasia, Sontheimer, Erik J, Maehr, René, Garber, Manuel, Watts, Jonathan K

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins von Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E, Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D, Liu, Pengpeng, Davidson, Alan R, Maxwell, Karen L, Sontheimer, Erik J

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CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro von Meijboom, Katharina E., Abdallah, Abbas, Fordham, Nicholas P., Nagase, Hiroko, Rodriguez, Tomás, Kraus, Carolyn, Gendron, Tania F., Krishnan, Gopinath, Esanov, Rustam, Andrade, Nadja S., Rybin, Matthew J., Ramic, Melina, Stephens, Zachary D., Edraki, Alireza, Blackwood, Meghan T., Kahriman, Aydan, Henninger, Nils, Kocher, Jean-Pierre A., Benatar, Michael, Brodsky, Michael H., Petrucelli, Leonard, Gao, Fen-Biao, Sontheimer, Erik J., Brown, Robert H., Zeier, Zane, Mueller, Christian

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