FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy von Chen, Xin, Song, Xiaomin, Li, Kang, Zhang, Tong

Volltext

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase von Guo, Yunhang, Liu, Ye, Hu, Nan, Yu, Desheng, Zhou, Changyou, Shi, Gongyin, Zhang, Bo, Wei, Min, Liu, Junhua, Luo, Lusong, Tang, Zhiyu, Song, Huipeng, Guo, Yin, Liu, Xuesong, Su, Dan, Zhang, Shuo, Song, Xiaomin, Zhou, Xing, Hong, Yuan, Chen, Shuaishuai, Cheng, Zhenzhen, Young, Steve, Wei, Qiang, Wang, Haisheng, Wang, Qiuwen, Lv, Lei, Wang, Fan, Xu, Haipeng, Sun, Hanzi, Xing, Haimei, Li, Na, Zhang, Wei, Wang, Zhongbo, Liu, Guodong, Sun, Zhijian, Zhou, Dongping, Li, Wei, Liu, Libin, Wang, Lai, Wang, Zhiwei

Volltext

Foxp3 Post-translational Modifications and Treg Suppressive Activity von Deng, Guoping, Song, Xiaomin, Fujimoto, Shigeyoshi, Piccirillo, Ciriaco A, Nagai, Yasuhiro, Greene, Mark I

Volltext

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer von Jiao, Shi, Wang, Huizhen, Shi, Zhubing, Dong, Aimei, Zhang, Wenjing, Song, Xiaomin, He, Feng, Wang, Yicui, Zhang, Zhenzhen, Wang, Wenjia, Wang, Xin, Guo, Tong, Li, Peixue, Zhao, Yun, Ji, Hongbin, Zhang, Lei, Zhou, Zhaocai

Volltext

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1 von Xu, Junjie, Ji, Lin, Liang, Yuelong, Wan, Zhe, Zheng, Wei, Song, Xiaomin, Gorshkov, Kirill, Sun, Qiming, Lin, Hui, Zheng, Xueyong, Chen, Jiang, Jin, Ren-an, Liang, Xiao, Cai, Xiujun

Volltext

regulatory mechanism of Hsp90α secretion and its function in tumor malignancy von Wang, Xiaofeng, Song, Xiaomin, Zhuo, Wei, Fu, Yan, Shi, Hubing, Liang, Yun, Tong, Maomeng, Chang, Guodong, Luo, Yongzhang

Volltext

SWATH Mass Spectrometry Performance Using Extended Peptide MS/MS Assay Libraries von Wu, Jemma X., Song, Xiaomin, Pascovici, Dana, Zaw, Thiri, Care, Natasha, Krisp, Christoph, Molloy, Mark P.

Volltext

Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice von Rhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Dröse, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Götz, Jürgen, Eckert, Anne

Volltext

Tumor-Associated Macrophages Promote Angiogenesis and Melanoma Growth via Adrenomedullin in a Paracrine and Autocrine Manner von PEIWEN CHEN, YUJIE HUANG, BONG, Rosabel, YANPING DING, NAN SONG, XIAOFENG WANG, XIAOMIN SONG, YONGZHANG LUO

Volltext

Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor von Xiong, Yao, Guo, Yin, Liu, Ye, Wang, Hexiang, Gong, Wenfeng, Liu, Yong, Wang, Xing, Gao, Yajuan, Yu, Fenglong, Su, Dan, Wang, Fan, Zhu, Yutong, Zhao, Yuan, Wu, Yiyuan, Qin, Zhen, Sun, Xuebing, Ren, Bo, Jiang, Bin, Jin, Wei, Shen, Zhirong, Tang, Zhiyu, Song, Xiaomin, Wang, Lai, Liu, Xuesong, Zhou, Changyou, Jiang, Beibei

Volltext

The CXCL12―CXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis von WEI ZHUO, LIN JIA, NAN SONG, LU, Xin-An, YANPING DING, XIAOFENG WANG, XIAOMIN SONG, YAN FU, YONGZHANG LUO

Volltext

Synergistic effect of poly (ADP-ribose) polymerase (PARP) inhibitor with chemotherapy on CXorf67-elevated posterior fossa group A ependymoma von Han, Jichang, Yu, Jianzhong, Yu, Meng, Liu, Yachao, Song, Xiaomin, Li, Hao, Li, Lin

Volltext

An Fc-Competent Anti-Human TIGIT Blocking Antibody Ociperlimab (BGB-A1217) Elicits Strong Immune Responses and Potent Anti-Tumor Efficacy in Pre-Clinical Models von Chen, Xin, Xue, Liu, Ding, Xiao, Zhang, Jing, Jiang, Lei, Liu, Sha, Hou, Hongjia, Jiang, Bin, Cheng, Liang, Zhu, Qing, Zhang, Lijie, Zhou, Xiaosui, Ma, Jie, Liu, Qi, Li, Yucheng, Ren, Zhiying, Jiang, Beibei, Song, Xiaomin, Song, Jing, Jin, Wei, Wei, Min, Shen, Zhirong, Liu, Xuesong, Wang, Lai, Li, Kang, Zhang, Tong

Volltext

TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathway von Luan, Xiaoyu, Chen, Peng, Li, Yaxin, Yuan, Xinying, Miao, Longyu, Zhang, Pengyu, Cao, Qilong, Song, Xiaomin, Di, Guohu

Volltext

Differential effects of BTK inhibitors ibrutinib and zanubrutinib on NK-cell effector function in patients with mantle cell lymphoma von Flinsenberg, Thijs W. H., Tromedjo, Charnelle C., Hu, Nan, Liu, Ye, Guo, Yin, Thia, Kevin Y. T., Noori, Tahereh, Song, Xiaomin, Aw Yeang, Han X., Tantalo, Daniela G., Handunnetti, Sasanka, Seymour, John F., Roberts, Andrew W., Ritchie, David, Koldej, Rachel, Neeson, Paul J., Wang, Lai, Trapani, Joseph A., Tam, Constantine S., Voskoboinik, Ilia

Volltext

Pathophysiological pathway differences in children who present with COVID-19 ARDS compared to COVID -19 induced MIS-C von McCafferty, Conor, Cai, Tengyi, Borgel, Delphine, Lasne, Dominique, Renolleau, Sylvain, Vedrenne-Cloquet, Meryl, Bonnet, Damien, Wu, Jemma, Zaw, Thiri, Bhatnagar, Atul, Song, Xiaomin, Van Den Helm, Suelyn, Letunica, Natasha, Attard, Chantal, Karlaftis, Vasiliki, Praporski, Slavica, Ignjatovic, Vera, Monagle, Paul

Volltext

A highly selective PI3Kδ inhibitor BGB-10188 shows superior preclinical anti-tumor activities and decreased on-target side effects on colon von Yang, Xiao, Bai, Huichen, Yuan, Xi, Yang, Xiaolong, Liu, Ye, Guo, Mingming, Hu, Nan, Jiang, Beibei, Lian, Zeqin, Ma, Zhilong, Wang, Jingyuan, Sun, Xuebing, Zhang, Taichang, Su, Dan, Wu, Yue, Li, Jing, Wang, Fan, Wang, Zhiwei, Wang, Lai, Liu, Xuesong, Song, Xiaomin

Volltext

Tislelizumab uniquely binds to the CC′ loop of PD‐1 with slow‐dissociated rate and complete PD‐L1 blockage von Hong, Yuan, Feng, Yingcai, Sun, Hanzi, Zhang, Bo, Wu, Hongfu, Zhu, Qing, Li, Yucheng, Zhang, Tong, Zhang, Yilu, Cui, Xinxin, Li, Zhuo, Song, Xiaomin, Li, Kang, Liu, Mike, Liu, Ye

Volltext

Overexpression of Platelet-Derived Growth Factor-BB Increases Tumor Pericyte Content via Stromal-Derived Factor-1 α/CXCR4 Axis von Song, Nan, Huang, Yujie, Shi, Hubing, Yuan, Shaopeng, Ding, Yanping, Song, Xiaomin, Fu, Yan, Luo, Yongzhang

Volltext

Enzymes and Metabolites in Carbohydrate Metabolism of Desiccation Tolerant Plants von Zhang, Qingwei, Song, Xiaomin, Bartels, Dorothea

Volltext