Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer von Unterleuthner, Daniela, Neuhold, Patrick, Schwarz, Katharina, Janker, Lukas, Neuditschko, Benjamin, Nivarthi, Harini, Crncec, Ilija, Kramer, Nina, Unger, Christine, Hengstschläger, Markus, Eferl, Robert, Moriggl, Richard, Sommergruber, Wolfgang, Gerner, Christopher, Dolznig, Helmut

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Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages von Stadler, Mira, Pudelko, Karoline, Biermeier, Alexander, Walterskirchen, Natalie, Gaigneaux, Anthoula, Weindorfer, Claudia, Harrer, Nathalie, Klett, Hagen, Hengstschläger, Markus, Schüler, Julia, Sommergruber, Wolfgang, Oehler, Rudolf, Bergmann, Michael, Letellier, Elisabeth, Dolznig, Helmut

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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery von Stock, Kristin, Estrada, Marta F., Vidic, Suzana, Gjerde, Kjersti, Rudisch, Albin, Santo, Vítor E., Barbier, Michaël, Blom, Sami, Arundkar, Sharath C., Selvam, Irwin, Osswald, Annika, Stein, Yan, Gruenewald, Sylvia, Brito, Catarina, van Weerden, Wytske, Rotter, Varda, Boghaert, Erwin, Oren, Moshe, Sommergruber, Wolfgang, Chong, Yolanda, de Hoogt, Ronald, Graeser, Ralph

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1495 Non-small cell lung cancer cells shape their tumor microenvironment towards a distinct inflammatory profile in vitro based on their molecular and phenotypic characteristics von Schueler, Julia, Harrer, Nathalie, Machat, Herwig, Sommergruber, Wolfgang

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KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth von Raho, Susanna, Capobianco, Loredana, Malivindi, Rocco, Vozza, Angelo, Piazzolla, Carmela, De Leonardis, Francesco, Gorgoglione, Ruggiero, Scarcia, Pasquale, Pezzuto, Francesca, Agrimi, Gennaro, Barile, Simona N., Pisano, Isabella, Reshkin, Stephan J., Greco, Maria R., Cardone, Rosa A., Rago, Vittoria, Li, Yuan, Marobbio, Carlo M. T., Sommergruber, Wolfgang, Riley, Christopher L., Lasorsa, Francesco M., Mills, Edward, Vegliante, Maria C., De Benedetto, Giuseppe E., Fratantonio, Deborah, Palmieri, Luigi, Dolce, Vincenza, Fiermonte, Giuseppe

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CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia von Gluexam, Tobias, Grandits, Alexander M, Schlerka, Angela, Nguyen, Chi Huu, Etzler, Julia, Finkes, Thomas, Fuchs, Michael, Scheid, Christoph, Heller, Gerwin, Hackl, Hubert, Harrer, Nathalie, Sill, Heinz, Koller, Elisabeth, Stoiber, Dagmar, Sommergruber, Wolfgang, Wieser, Rotraud

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High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal... von Rudisch, Albin, Dewhurst, Matthew Richard, Horga, Luminita Gabriela, Kramer, Nina, Harrer, Nathalie, Dong, Meng, van der Kuip, Heiko, Wernitznig, Andreas, Bernthaler, Andreas, Dolznig, Helmut, Sommergruber, Wolfgang

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PI3Kβ inhibition enhances ALK‐inhibitor sensitivity in ALK‐rearranged lung cancer von Talwelkar, Sarang S., Mäyränpää, Mikko I., Schüler, Julia, Linnavirta, Nora, Hemmes, Annabrita, Adinolfi, Simone, Kankainen, Matti, Sommergruber, Wolfgang, Levonen, Anna‐Liisa, Räsänen, Jari, Knuuttila, Aija, Verschuren, Emmy W., Wennerberg, Krister

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1496 Deciphering the influence of different cell types shaping the tumor microenvironment of lung cancer in an invitro multicellular assay von Schueler, Julia, Loehr, Anne, Groene, Lea, Edinger, Anna, Harrer, Nathalie, Sommergruber, Wolfgang

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Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation von Klein, Rüdiger, Ferby, Ingvar, Reschke, Markus, Kudlacek, Oliver, Knyazev, Pjotr, Pantè, Guido, Amann, Kerstin, Sommergruber, Wolfgang, Kraut, Norbert, Ullrich, Axel, Fässler, Reinhard

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Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients von Lipp, Jesse J., Wang, Limei, Yang, Haitang, Yao, Feng, Harrer, Nathalie, Müller, Stefan, Berezowska, Sabina, Dorn, Patrick, Marti, Thomas M., Schmid, Ralph A., Hegedüs, Belazs, Souabni, Abdallah, Carotta, Sebastian, Pearson, Mark A., Sommergruber, Wolfgang, Kocher, Greg J., Hall, Sean R.R.

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Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes von AMATSCHEK, Stefan, KOENIG, Ulrich, STRATOWA, Christian, SCHREIBER, Martin, SOMMERGRUBER, Wolfgang, AUER, Herbert, STEINLEIN, Peter, PACHER, Margit, GRUENFELDER, Agnes, DEKAN, Gerhard, VOGL, Sonja, KUBISTA, Ernst, HEIDER, Karl-Heinz

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Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer von Wang, Limei, Yang, Haitang, Dorn, Patrick, Berezowska, Sabina, Blank, Fabian, Wotzkow, Carlos, Marti, Thomas M., Peng, Ren-Wang, Harrer, Nathalie, Sommergruber, Wolfgang, Kocher, Gregor J., Schmid, Ralph A., Hall, Sean R.R.

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The transcription factor ZEB1 (δEF1) represses Plakophilin 3 during human cancer progression von Aigner, Kirsten, Descovich, Luise, Mikula, Mario, Sultan, Aneesa, Dampier, Brigitta, Bonné, Stefan, van Roy, Frans, Mikulits, Wolfgang, Schreiber, Martin, Brabletz, Thomas, Sommergruber, Wolfgang, Schweifer, Norbert, Wernitznig, Andreas, Beug, Hartmut, Foisner, Roland, Eger, Andreas

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Induction of Acquired Resistance towards EGFR Inhibitor Gefitinib in a Patient-Derived Xenograft Model of Non-Small Cell Lung Cancer and Subsequent Molecular Characterization von Schueler, Julia, Tschuch, Cordula, Klingner, Kerstin, Bug, Daniel, Peille, Anne-Lise, de Koning, Leanne, Oswald, Eva, Klett, Hagen, Sommergruber, Wolfgang

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Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells von Pacher, Margit, Seewald, Michael J., Mikula, Mario, Oehler, Susanne, Mogg, Maurice, Vinatzer, Ursula, Eger, Andreas, Schweifer, Norbert, Varecka, Roland, Sommergruber, Wolfgang, Mikulits, Wolfgang, Schreiber, Martin

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Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer von SCHERL-MOSTAGEER, Marwa, SOMMERGRUBER, Wolfgang, ABSEHER, Roger, HAUPTMANN, Rudolf, AMBROS, Peter, SCHWEIFER, Norbert

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hGPR87 contributes to viability of human tumor cells von Glatt, Sebastian, Halbauer, Daniel, Heindl, Stefan, Wernitznig, Andreas, Kozina, Daniela, Su, Kuan‐Chung, Puri, Christina, Garin‐Chesa, Pilar, Sommergruber, Wolfgang

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Aberrant expression of caspase-14 in epithelial tumors von Koenig, Ulrich, Sommergruber, Wolfgang, Lippens, Saskia

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BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy von Hilberg, Frank, Roth, Gerald J, Krssak, Martin, Kautschitsch, Susanna, Sommergruber, Wolfgang, Tontsch-Grunt, Ulrike, Garin-Chesa, Pilar, Bader, Gerd, Zoephel, Andreas, Quant, Jens, Heckel, Armin, Rettig, Wolfgang J

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