The making of insulin in health and disease von Vasiljević, Jovana, Torkko, Juha M., Knoch, Klaus-Peter, Solimena, Michele

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Viral infiltration of pancreatic islets in patients with COVID-19 von Steenblock, Charlotte, Richter, Stefanie, Berger, Ilona, Barovic, Marko, Schmid, Janine, Schubert, Undine, Jarzebska, Natalia, von Mässenhausen, Anne, Linkermann, Andreas, Schürmann, Annette, Pablik, Jessica, Dienemann, Thomas, Evert, Katja, Rodionov, Roman N., Semenova, Natalia Y., Zinserling, Vsevolod A., Gainetdinov, Raul R., Baretton, Gustavo, Lindemann, Dirk, Solimena, Michele, Ludwig, Barbara, Bornstein, Stefan R.

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The insulin secretory granule as a signaling hub von Suckale, Jakob, Solimena, Michele

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Metabolic implications of pancreatic fat accumulation von Wagner, Robert, Eckstein, Sabine S., Yamazaki, Hajime, Gerst, Felicia, Machann, Jürgen, Jaghutriz, Benjamin Assad, Schürmann, Annette, Solimena, Michele, Singer, Stephan, Königsrainer, Alfred, Birkenfeld, Andreas L., Häring, Hans-Ulrich, Fritsche, Andreas, Ullrich, Susanne, Heni, Martin

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Content-aware image restoration: pushing the limits of fluorescence microscopy von Weigert, Martin, Schmidt, Uwe, Boothe, Tobias, Müller, Andreas, Dibrov, Alexandr, Jain, Akanksha, Wilhelm, Benjamin, Schmidt, Deborah, Broaddus, Coleman, Culley, Siân, Rocha-Martins, Mauricio, Segovia-Miranda, Fabián, Norden, Caren, Henriques, Ricardo, Zerial, Marino, Solimena, Michele, Rink, Jochen, Tomancak, Pavel, Royer, Loic, Jug, Florian, Myers, Eugene W.

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Transplantation of human islets without immunosuppression von Ludwig, Barbara, Reichel, Andreas, Steffen, Anja, Zimerman, Baruch, Schally, Andrew V., Block, Norman L., Colton, Clark K., Ludwig, Stefan, Kersting, Stephan, Bonifacio, Ezio, Solimena, Michele, Gendler, Zohar, Rotem, Avi, Barkai, Uriel, Bornstein, Stefan R.

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Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis von Cohrs, Christian M., Panzer, Julia K., Drotar, Denise M., Enos, Stephen J., Kipke, Nicole, Chen, Chunguang, Bozsak, Robert, Schöniger, Eyke, Ehehalt, Florian, Distler, Marius, Brennand, Ana, Bornstein, Stefan R., Weitz, Jürgen, Solimena, Michele, Speier, Stephan

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Adaptive lipid packing and bioactivity in membrane domains von Sezgin, Erdinc, Gutmann, Theresia, Buhl, Tomasz, Dirkx, Ron, Grzybek, Michal, Coskun, Ünal, Solimena, Michele, Simons, Kai, Levental, Ilya, Schwille, Petra

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The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers von Monzón-Casanova, Elisa, Screen, Michael, Díaz-Muñoz, Manuel D., Coulson, Richard M. R., Bell, Sarah E., Lamers, Greta, Solimena, Michele, Smith, Christopher W. J., Turner, Martin

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Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes von Marselli, Lorella, Piron, Anthony, Suleiman, Mara, Colli, Maikel L., Yi, Xiaoyan, Khamis, Amna, Carrat, Gaelle R., Rutter, Guy A., Bugliani, Marco, Giusti, Laura, Ronci, Maurizio, Ibberson, Mark, Turatsinze, Jean-Valery, Boggi, Ugo, De Simone, Paolo, De Tata, Vincenzo, Lopes, Miguel, Nasteska, Daniela, De Luca, Carmela, Tesi, Marta, Bosi, Emanuele, Singh, Pratibha, Campani, Daniela, Schulte, Anke M., Solimena, Michele, Hecht, Peter, Rady, Brian, Bakaj, Ivona, Pocai, Alessandro, Norquay, Lisa, Thorens, Bernard, Canouil, Mickaël, Froguel, Philippe, Eizirik, Decio L., Cnop, Miriam, Marchetti, Piero

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Structure, interaction and nervous connectivity of beta cell primary cilia von Müller, Andreas, Klena, Nikolai, Pang, Song, Garcia, Leticia Elizabeth Galicia, Topcheva, Oleksandra, Aurrecoechea Duran, Solange, Sulaymankhil, Davud, Seliskar, Monika, Mziaut, Hassan, Schöniger, Eyke, Friedland, Daniela, Kipke, Nicole, Kretschmar, Susanne, Münster, Carla, Weitz, Jürgen, Distler, Marius, Kurth, Thomas, Schmidt, Deborah, Hess, Harald F., Xu, C. Shan, Pigino, Gaia, Solimena, Michele

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OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion von Panagiotou, Styliani, Tan, Kia Wee, Nguyen, Phuoc My, Müller, Andreas, Oqua, Affiong Ika, Tomas, Alejandra, Wendt, Anna, Eliasson, Lena, Tengholm, Anders, Solimena, Michele, Idevall-Hagren, Olof

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Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies von Hoboth, Peter, Müller, Andreas, Ivanova, Anna, Mziaut, Hassan, Dehghany, Jaber, Sönmez, Anke, Lachnit, Martina, Meyer-Hermann, Michael, Kalaidzidis, Yannis, Solimena, Michele

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Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes von Wigger, Leonore, Barovic, Marko, Brunner, Andreas-David, Marzetta, Flavia, Schöniger, Eyke, Mehl, Florence, Kipke, Nicole, Friedland, Daniela, Burdet, Frederic, Kessler, Camille, Lesche, Mathias, Thorens, Bernard, Bonifacio, Ezio, Legido-Quigley, Cristina, Barbier Saint Hilaire, Pierre, Delerive, Philippe, Dahl, Andreas, Klose, Christian, Gerl, Mathias J., Simons, Kai, Aust, Daniela, Weitz, Jürgen, Distler, Marius, Schulte, Anke M., Mann, Matthias, Ibberson, Mark, Solimena, Michele

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Purification of time-resolved insulin granules reveals proteomic and lipidomic changes during granule aging von Neukam, Martin, Sala, Pia, Brunner, Andreas-David, Ganß, Katharina, Palladini, Alessandra, Grzybek, Michal, Topcheva, Oleksandra, Vasiljević, Jovana, Broichhagen, Johannes, Johnsson, Kai, Kurth, Thomas, Mann, Matthias, Coskun, Ünal, Solimena, Michele

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The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance von Phieler, Julia, Chung, Kyoung-Jin, Chatzigeorgiou, Antonios, Klotzsche-von Ameln, Anne, Garcia-Martin, Ruben, Sprott, David, Moisidou, Maria, Tzanavari, Theodora, Ludwig, Barbara, Baraban, Elena, Ehrhart-Bornstein, Monika, Bornstein, Stefan R, Mziaut, Hassan, Solimena, Michele, Karalis, Katia P, Economopoulou, Matina, Lambris, John D, Chavakis, Triantafyllos

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enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway von Shin, Hye-Won, Hayashi, Mitsuko, Christoforidis, Savvas, Lacas-Gervais, Sandra, Hoepfner, Sebastian, Wenk, Markus R, Modregger, Jan, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Nystuen, Arne, Frankel, Wayne N, Solimena, Michele, De Camilli, Pietro, Zerial, Marino

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A Global Approach for Quantitative Super Resolution and Electron Microscopy on Cryo and Epoxy Sections Using Self-labeling Protein Tags von Müller, Andreas, Neukam, Martin, Ivanova, Anna, Sönmez, Anke, Münster, Carla, Kretschmar, Susanne, Kalaidzidis, Yannis, Kurth, Thomas, Verbavatz, Jean-Marc, Solimena, Michele

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Plasma triacylglycerols are biomarkers of β-cell function in mice and humans von Sánchez-Archidona, Ana Rodríguez, Cruciani-Guglielmacci, Céline, Roujeau, Clara, Wigger, Leonore, Lallement, Justine, Denom, Jessica, Barovic, Marko, Kassis, Nadim, Mehl, Florence, Weitz, Jurgen, Distler, Marius, Klose, Christian, Simons, Kai, Ibberson, Mark, Solimena, Michele, Magnan, Christophe, Thorens, Bernard

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Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study von Imam, Akram, Winnebeck, Eva C, Buchholz, Nina, Froguel, Philippe, Bonnefond, Amélie, Solimena, Michele, Ivanova, Anna, Bouvier, Michel, Plouffe, Bianca, Charpentier, Guillaume, Karamitri, Angeliki, Jockers, Ralf, Roenneberg, Till, Vetter, Céline

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