Structural basis for selectivity and diversity in angiotensin II receptors von Zhang, Haitao, Han, Gye Won, Batyuk, Alexander, Ishchenko, Andrii, White, Kate L., Patel, Nilkanth, Sadybekov, Anastasiia, Zamlynny, Beata, Rudd, Michael T., Hollenstein, Kaspar, Tolstikova, Alexandra, White, Thomas A., Hunter, Mark S., Weierstall, Uwe, Liu, Wei, Babaoglu, Kerim, Moore, Eric L., Katz, Ryan D., Shipman, Jennifer M., Garcia-Calvo, Margarita, Sharma, Sujata, Sheth, Payal, Soisson, Stephen M., Stevens, Raymond C., Katritch, Vsevolod, Cherezov, Vadim

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Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40 von Lu, Jun, Byrne, Noel, Wang, John, Bricogne, Gerard, Brown, Frank K, Chobanian, Harry R, Colletti, Steven L, Di Salvo, Jerry, Thomas-Fowlkes, Brande, Guo, Yan, Hall, Dawn L, Hadix, Jennifer, Hastings, Nicholas B, Hermes, Jeffrey D, Ho, Thu, Howard, Andrew D, Josien, Hubert, Kornienko, Maria, Lumb, Kevin J, Miller, Michael W, Patel, Sangita B, Pio, Barbara, Plummer, Christopher W, Sherborne, Bradley S, Sheth, Payal, Souza, Sarah, Tummala, Srivanya, Vonrhein, Clemens, Webb, Maria, Allen, Samantha J, Johnston, Jennifer M, Weinglass, Adam B, Sharma, Sujata, Soisson, Stephen M

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A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein von Tang, Aimin, Chen, Zhifeng, Cox, Kara S., Su, Hua-Poo, Callahan, Cheryl, Fridman, Arthur, Zhang, Lan, Patel, Sangita B., Cejas, Pedro J., Swoyer, Ryan, Touch, Sinoeun, Citron, Michael P., Govindarajan, Dhanasekaran, Luo, Bin, Eddins, Michael, Reid, John C., Soisson, Stephen M., Galli, Jennifer, Wang, Dai, Wen, Zhiyun, Heidecker, Gwendolyn J., Casimiro, Danilo R., DiStefano, Daniel J., Vora, Kalpit A.

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Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation von Hong, Chuan, Byrne, Noel J., Zamlynny, Beata, Tummala, Srivanya, Xiao, Li, Shipman, Jennifer M., Partridge, Andrea T., Minnick, Christina, Breslin, Michael J., Rudd, Michael T., Stachel, Shawn J., Rada, Vanessa L., Kern, Jeffrey C., Armacost, Kira A., Hollingsworth, Scott A., O’Brien, Julie A., Hall, Dawn L., McDonald, Terrence P., Strickland, Corey, Brooun, Alexei, Soisson, Stephen M., Hollenstein, Kaspar

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Biostructural, biochemical and biophysical studies of mutant IDH1 von McCoy, Mark A., Lu, Jun, Richard Miller, F., Soisson, Stephen M., Lam, Michael H., Fischer, Christian

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A non-canonical mechanism of GPCR activation von Powers, Alexander S., Khan, Aasma, Paggi, Joseph M., Latorraca, Naomi R., Souza, Sarah, Di Salvo, Jerry, Lu, Jun, Soisson, Stephen M., Johnston, Jennifer M., Weinglass, Adam B., Dror, Ron O.

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Mechanism of Action of the Cell-Division Inhibitor PC190723: Modulation of FtsZ Assembly Cooperativity von Elsen, Nathaniel L, Lu, Jun, Parthasarathy, Gopal, Reid, John C, Sharma, Sujata, Soisson, Stephen M, Lumb, Kevin J

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Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase von Hayes, Robert P., Heo, Mee Ra, Mason, Mark, Reid, John, Burlein, Christine, Armacost, Kira A., Tellers, David M., Raheem, Izzat, Shaw, Anthony W., Murray, Edward, McKenna, Philip M., Abeywickrema, Pravien, Sharma, Sujata, Soisson, Stephen M., Klein, Daniel

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Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U‑Shaped Binding Mode von Lu, Jun, Patel, Sangita, Sharma, Nandini, Soisson, Stephen M, Kishii, Ryuta, Takei, Masaya, Fukuda, Yasumichi, Lumb, Kevin J, Singh, Sheo B

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Structural insights on ligand recognition at the human leukotriene B4 receptor 1 von Michaelian, Nairie, Sadybekov, Anastasiia, Besserer-Offroy, Élie, Han, Gye Won, Krishnamurthy, Harini, Zamlynny, Beata A., Fradera, Xavier, Siliphaivanh, Phieng, Presland, Jeremy, Spencer, Kerrie B., Soisson, Stephen M., Popov, Petr, Sarret, Philippe, Katritch, Vsevolod, Cherezov, Vadim

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Structural Analysis of Autoinhibition in the Ras Activator Son of Sevenless von Sondermann, Holger, Soisson, Stephen M., Boykevisch, Sean, Yang, Shao-Song, Bar-Sagi, Dafna, Kuriyan, John

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Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer von Clayton, Gina M., Klein, Daniel J., Rickert, Keith W., Patel, Sangita B., Kornienko, Maria, Zugay-Murphy, Joan, Reid, John C., Tummala, Srivanya, Sharma, Sujata, Singh, Sheo B., Miesel, Lynn, Lumb, Kevin J., Soisson, Stephen M.

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Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation von Soisson, Stephen M, Parthasarathy, Gopalakrishnan, Adams, Alan D, Sahoo, Soumya, Sitlani, Ayesha, Sparrow, Carl, Cui, Jisong, Becker, Joseph W

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Insights into activity and inhibition from the crystal structure of human O-GlcNAcase von Elsen, Nathaniel L, Patel, Sangita B, Ford, Rachael E, Hall, Dawn L, Hess, Fred, Kandula, Hari, Kornienko, Maria, Reid, John, Selnick, Harold, Shipman, Jennifer M, Sharma, Sujata, Lumb, Kevin J, Soisson, Stephen M, Klein, Daniel J

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Synthesis and biological evaluation of platensimycin analogs von SHEN, Hong C, DING, Fa-Xiang, TATA, James R, HAMMOND, Milton L, MACCOSS, Malcolm, COLLETTI, Steven L, SINGH, Sheo B, PARTHASARATHY, Gopalakrishnan, SOISSON, Stephen M, HA, Sookhee N, XUN CHEN, KODALI, Srinivas, JUN WANG, DORSO, Karen

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Structural Basis for Ligand-Regulated Oligomerization of AraC von Soisson, Stephen M., MacDougall-Shackleton, Beth, Schleif, Robert, Wolberger, Cynthia

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Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates von Wu, Chengwei, Raheem, Izzat T, Nahas, Debbie D, Citron, Michael, Kim, Peter S, Montefiori, David C, Ottinger, Elizabeth A, Hepler, Robert W, Hrin, Renee, Patel, Sangita B, Soisson, Stephen M, Joyce, Joseph G

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 von Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, Alison M., Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.

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Identification of an allosteric binding site for RORγt inhibition von Scheepstra, Marcel, Leysen, Seppe, van Almen, Geert C., Miller, J. Richard, Piesvaux, Jennifer, Kutilek, Victoria, van Eenennaam, Hans, Zhang, Hongjun, Barr, Kenneth, Nagpal, Sunil, Soisson, Stephen M., Kornienko, Maria, Wiley, Kristen, Elsen, Nathaniel, Sharma, Sujata, Correll, Craig C., Trotter, B. Wesley, van der Stelt, Mario, Oubrie, Arthur, Ottmann, Christian, Parthasarathy, Gopal, Brunsveld, Luc

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Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels von Chen, Yun-Ting, Hong, Mee Ra, Zhang, Xin-Jun, Kostas, James, Li, Yuxing, Kraus, Richard L, Santarelli, Vincent P, Wang, Deping, Gomez-Llorente, Yacob, Brooun, Alexei, Strickland, Corey, Soisson, Stephen M, Klein, Daniel J, Ginnetti, Anthony T, Marino, Michael J, Stachel, Shawn J, Ishchenko, Andrii

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