Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists von Karoutzou, Olga, Kwak, Seung-Hwa, Lee, So-Deok, Martínez-Falguera, Daina, Sureda, Francesc X, Vázquez, Santiago, Kim, Yong-Chul, Barniol-Xicota, Marta

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Discovery of orally active indirubin-3′-oxime derivatives as potent type 1 FLT3 inhibitors for acute myeloid leukemia von Jeong, Pyeonghwa, Moon, Yeongyu, Lee, Je-Heon, Lee, So-Deok, Park, Jiyeon, Lee, Jungeun, Kim, Jiheon, Lee, Hyo Jeong, Kim, Na Yoon, Choi, Jungil, Heo, Jeong Doo, Shin, Ji Eun, Park, Hyun Woo, Kim, Yoon-Gyoon, Han, Sun-Young, Kim, Yong-Chul

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Discovery of benzimidazole-indazole derivatives as potent FLT3-tyrosine kinase domain mutant kinase inhibitors for acute myeloid leukemia von Ko, Bongki, Jang, Yongsoo, Kim, Min Ha, Lam, Thai Thi, Seo, Hye Kyung, Jeong, Pyeonghwa, Choi, Munkyung, Kang, Keon Wook, Lee, So-Deok, Park, Jin-Hee, Kim, Myungjin, Han, Sun-Young, Kim, Yong-Chul

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Discovery of Novel 2,5-Dioxoimidazolidine-Based P2X7 Receptor Antagonists as Constrained Analogues of KN62 von Park, Jin-Hee, Lee, Ga-Eun, Lee, So-Deok, Hien, Tran Thi, Kim, Sujin, Yang, Jin Won, Cho, Joong-Heui, Ko, Hyojin, Lim, Sung-Chul, Kim, Yoon-Gyoon, Kang, Keon-Wook, Kim, Yong-Chul

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Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells von Kwak, Seung-Hwa, Shin, Seungheon, Lee, Ji-Hyun, Shim, Jin-Kyoung, Kim, Minjeong, Lee, So-Deok, Lee, Aram, Bae, Jinsu, Park, Jin-Hee, Abdelrahman, Aliaa, Müller, Christa E., Cho, Steve K., Kang, Seok-Gu, Bae, Myung Ae, Yang, Jung Yoon, Ko, Hyojin, Goddard, William A., Kim, Yong-Chul

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Nanoparticle-encapsulated P2X7 receptor antagonist in a pH-sensitive polymer as a potential local drug delivery system to acidic inflammatory environments von Lee, Sun-Mi, Cho, Joong-Heui, Lee, So-Deok, Kim, Yong-Chul

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5,5′-Substituted Indirubin-3′-oxime Derivatives as Potent Cyclin-Dependent Kinase Inhibitors with Anticancer Activity von Choi, Soo-Jeong, Lee, Jung-Eun, Jeong, Soon-Young, Im, Isak, Lee, So-Deok, Lee, Eun-Jin, Lee, Sang Kook, Kwon, Seong-Min, Ahn, Sang-Gun, Yoon, Jung-Hoon, Han, Sun-Young, Kim, Jae-Il, Kim, Yong-Chul

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Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles von Barniol-Xicota, Marta, Kwak, Seung-Hwa, Lee, So-Deok, Caseley, Emily, Valverde, Elena, Jiang, Lin-Hua, Kim, Yong-Chul, Vázquez, Santiago

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Structure–activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists von Park, Jin-Hee, Lee, Ga-Eun, Lee, So-Deok, Ko, Hyojin, Kim, Yong-Chul

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Discovery and structure–activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents von Kwak, Seung-Hwa, Kang, Jung-Ah, Kim, Minjeong, Lee, So-Deok, Park, Jin-Hee, Park, Sung-Gyoo, Ko, Hyojin, Kim, Yong-Chul

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Discovery of Potent Antiallodynic Agents for Neuropathic Pain Targeting P2X3 Receptors von Jung, Young-Hwan, Kim, Yeo Ok, Lin, Hai, Cho, Joong-Heui, Park, Jin-Hee, Lee, So-Deok, Bae, Jinsu, Kang, Koon Mook, Kim, Yoon-Gyoon, Pae, Ae Nim, Ko, Hyojin, Park, Chul-Seung, Yoon, Myung Ha, Kim, Yong-Chul

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Solid-Phase Synthesis of Quinolinone Library von Kwak, Seung-hwa, Kim, Min jeong, Lee, So-Deok, You, Hyun, Kim, Yong-Chul, Ko, Hyojin

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Structure–Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X 7 Receptor Antagonists von Lee, Won-Gil, Lee, So-Deok, Cho, Joong-Heui, Jung, Younghwan, Kim, Jeong-hyun, Hien, Tran T., Kang, Keon-Wook, Ko, Hyojin, Kim, Yong-Chul

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Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors von Choi, Soo-Jeong, Cho, Joong-Heui, Im, Isak, Lee, So-Deok, Jang, Ji-Yeon, Oh, Yu-Min, Jung, Yong-Keun, Jeon, Eun-Seok, Kim, Yong-Chul

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Development of anti-coxsackievirus agents targeting 3C protease von Kim, Bo-Kyoung, Kim, Jeong-Hyun, Kim, Na-Ri, Lee, Won-Gil, Lee, So-Deok, Yun, Soo-Hyeon, Jeon, Eun-Seok, Kim, Yong-Chul

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Discovery of novel purine-based heterocyclic P2X7 receptor antagonists von Kwak, Seung-Hwa, Lee, Won-Gil, Lee, Yun-Jin, Lee, So-Deok, Kim, Yong-Chul, Ko, Hyojin

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Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells von Choi, Soo Jeong, Moon, Myoung Ju, Lee, So Deok, Choi, Sang-Un, Han, Sun-Young, Kim, Yong-Chul

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Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists von GA EUN LEE, LEE, Ho-Sung, SO DEOK LEE, KIM, Jung-Ho, KIM, Won-Ki, KIM, Yong-Chul

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Development of PLM-102, a novel dual inhibitor of FLT3 and RET as a new therapeutic option for acute myeloid leukemia von Kim, Myungjin, Oh, Su-jin, Kim, WooChan, Choi, Yong June, Lee, Jae-Seon, Lee, So-Deok, Park, Jin-Hee, Lee, Eun Ji, Kang, Keon Wook, Jang, Soo Yeon, Kim, Yong-Chul

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Potent Suppressive Effects of 1‑Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion von Park, Jin-Hee, Williams, Darren R, Lee, Ji-Hyung, Lee, So-Deok, Lee, Je-Heon, Ko, Hyojin, Lee, Ga-Eun, Kim, Sujin, Lee, Jeong-Min, Abdelrahman, Aliaa, Müller, Christa E, Jung, Da-Woon, Kim, Yong-Chul

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