Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction von Miyazawa, Kazuo, Ito, Kaoru, Ito, Masamichi, Zou, Zhaonan, Kubota, Masayuki, Nomura, Seitaro, Matsunaga, Hiroshi, Koyama, Satoshi, Ieki, Hirotaka, Akiyama, Masato, Koike, Yoshinao, Kurosawa, Ryo, Yoshida, Hiroki, Ozaki, Kouichi, Onouchi, Yoshihiro, Takahashi, Atsushi, Matsuda, Koichi, Murakami, Yoshinori, Aburatani, Hiroyuki, Kubo, Michiaki, Momozawa, Yukihide, Terao, Chikashi, Oki, Shinya, Akazawa, Hiroshi, Kamatani, Yoichiro, Komuro, Issei

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Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging von Timmers, Paul R. H. J., Tiys, Evgeny S., Sakaue, Saori, Akiyama, Masato, Kiiskinen, Tuomo T. J., Zhou, Wei, Hwang, Shih-Jen, Yao, Chen, Deelen, Joris, Levy, Daniel, Ganna, Andrea, Kamatani, Yoichiro, Okada, Yukinori, Joshi, Peter K., Wilson, James F., Tsepilov, Yakov A.

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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores von Weissbrod, Omer, Kanai, Masahiro, Shi, Huwenbo, Gazal, Steven, Peyrot, Wouter J., Khera, Amit V., Okada, Yukinori, Martin, Alicia R., Finucane, Hilary K., Price, Alkes L.

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Rare variant contribution to human disease in 281,104 UK Biobank exomes von Wang, Quanli, Dhindsa, Ryan S., Carss, Keren, Harper, Andrew R., Nag, Abhishek, Tachmazidou, Ioanna, Vitsios, Dimitrios, Deevi, Sri V. V., Mackay, Alex, Muthas, Daniel, Hühn, Michael, Monkley, Susan, Olsson, Henric, Wasilewski, Sebastian, Smith, Katherine R., March, Ruth, Platt, Adam, Haefliger, Carolina, Petrovski, Slavé

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Computational Analysis of Pumping Efficacy of a Left Ventricular Assist Device according to Cannulation Site in Heart Failure with Valvular Regurgitation von Heikhmakhtiar, Aulia Khamas, Lim, Ki Moo

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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents von Hayden, Frederick G, Sugaya, Norio, Hirotsu, Nobuo, Lee, Nelson, de Jong, Menno D, Hurt, Aeron C, Ishida, Tadashi, Sekino, Hisakuni, Yamada, Kota, Portsmouth, Simon, Kawaguchi, Keiko, Shishido, Takao, Arai, Masatsugu, Tsuchiya, Kenji, Uehara, Takeki, Watanabe, Akira

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Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries von Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.

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Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3... von Anderson, Craig S, Arima, Hisatomi, Chen, Guofang, Martins, Sheila O, Silva, Federico, Thang, Nguyen H, Arima, Hisatomi, Li, Qiang, Martins, Sheila O., Pontes-Neto, Octavio M., Wang, Xia, Simes, R. John, Hirakawa, Yoichiro, Moullaali, Tom J., Carcel, Cheryl, Gordon, Penny, Cao, Yongjun, Winters, Stephen, Zhang, Shihong, Manning, Lisa, Minhas, Jatinder, Malavera, Alejandra, Ivanova, Elizaveta, Armenis, Manuela, Blacklock, Nick, Naidu, Bala, Smith, Phillipa, Kong, Liang, Ebraimo, Ahtasam, Phuong, Do M., Tran, Nguyen T.B., Hoa, Nguyen A., Ray, E., Ng, G., Weiss, G., Titton, N., Castro, R., Fagundes, D., Alves, M., Rivas, R., Herrera, A., Zhou, S., Ping, L., Shi, J., Gong, P., Zhao, H., Li, R., Liu, D., Liang, L., Xia, J., Zhao, N., Huang, W., Zhang, A., Liu, H., Zhang, Y., Li, F., Huang, L., Zheng, R., Liu, J., Zhang, S., Liu, X., Lai, Y., Du, J., Wei, C., Li, W, Zeng, X., Wu, X., Castellanos, J.A., Raj, P.G., Parmar, M., Patel, D., Gorthi, S.P., Prabhu, A., Nair, R., TP, S., Choudhury, N., Duberkar, D., Sacchini, E., Padiglioni, C., Kim, J., Hwang, H.W., Kwon, S.U., Kim, Y.J., Kim, B., Kim, Y.W., Lee, J.J., Chang, H.M., Martínez, A., Lin, Y.J., Huang, Y.C., Dyker, A., Natarajan, I., Qadiri, M.R., Smith, C., James, M., Marsden, T., Price, C., Bergin, A., Le Kim, K., Le Thanh, T. Tran

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Genetic analysis of right heart structure and function in 40,000 people von Pirruccello, James P., Di Achille, Paolo, Nauffal, Victor, Nekoui, Mahan, Friedman, Samuel F., Klarqvist, Marcus D. R., Chaffin, Mark D., Weng, Lu-Chen, Cunningham, Jonathan W., Khurshid, Shaan, Roselli, Carolina, Lin, Honghuang, Koyama, Satoshi, Ito, Kaoru, Kamatani, Yoichiro, Komuro, Issei, Jurgens, Sean J., Benjamin, Emelia J., Batra, Puneet, Natarajan, Pradeep, Ng, Kenney, Hoffmann, Udo, Lubitz, Steven A., Ho, Jennifer E., Lindsay, Mark E., Philippakis, Anthony A., Ellinor, Patrick T.

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Successful establishment of crowdfunding to develop new diagnostic tools for chronic prostatitis von Tohi, Yoichiro, Kakehi, Yoshiyuki, Sugimoto, Mikio, Sugimoto, Mikio, Tohi, Yoichiro, Kakehi, Yoshiyuki, Hijikata, Yasukazu, Kuroda, Hideya, Takei, Mineo, Matsuki, Takakazu, Kamitani, Tsukasa, Fukuhara, Shunichi, Yamamoto, Yosuke

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Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs von Wang, Qingbo S., Kelley, David R., Ulirsch, Jacob, Kanai, Masahiro, Sadhuka, Shuvom, Cui, Ran, Albors, Carlos, Cheng, Nathan, Okada, Yukinori, Aguet, Francois, Ardlie, Kristin G., MacArthur, Daniel G., Finucane, Hilary K.

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Practical “1-2-3-4-Day” Rule for Starting Direct Oral Anticoagulants After Ischemic Stroke With Atrial Fibrillation: Combined Hospital-Based Cohort Study von Kimura, Shunsuke, Toyoda, Kazunori, Yoshimura, Sohei, Minematsu, Kazuo, Yasaka, Masahiro, Paciaroni, Maurizio, Werring, David J., Yamagami, Hiroshi, Nagao, Takehiko, Yoshimura, Shinichi, Polymeris, Alexandros, Zietz, Annaelle, Engelter, Stefan T., Kallmünzer, Bernd, Cappellari, Manuel, Chiba, Tetsuya, Yoshimoto, Takeshi, Shiozawa, Masayuki, Kitazono, Takanari, Koga, Masatoshi

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Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis von Sato, Go, Shirai, Yuya, Namba, Shinichi, Edahiro, Ryuya, Sonehara, Kyuto, Hata, Tsuyoshi, Uemura, Mamoru, Matsuda, Koichi, Doki, Yuichiro, Eguchi, Hidetoshi, Okada, Yukinori

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Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies von Chauhan, Ganesh, Arnold, Corey R, Chu, Audrey Y, Reyahi, Azadeh, Bis, Joshua C, Havulinna, Aki S, Trompet, Stella, Manichaikul, Ani, Teumer, Alexander, Gustafsson, Stefan, Bartz, Traci M, Bellenguez, Céline, Vidal, Jean Sebastien, Kjartansson, Olafur, Satizabal, Claudia L, Xue, Flora, Liu, Yongmei, Bevan, Steve, Hopewell, Jemma C, Heckbert, Susan R, Rice, Kenneth, Smith, Nicholas L, Levi, Christopher, Sharma, Pankaj, Sudlow, Cathie LM, Cole, John W, Schmidt, Reinhold, Meschia, James, Thijs, Vincent, Melander, Olle, Grewal, Raji P, Sacco, Ralph L, Rundek, Tatjana, Rothwell, Peter M, Jern, Christina, Johnson, Julie A, Benavente, Oscar R, Lee, Jin-Moo, Wong, Quenna, Aparicio, Hugo J, Engelter, Stefan T, Kloss, Manja, Pezzini, Alessandro, Buring, Julie E, Ridker, Paul M, Berr, Claudine, Dartigues, Jean-François, Hamsten, Anders, Traylor, Matthew, Pedersen, Nancy L, Lannfelt, Lars, Morris, Andrew P, Jimenez-Conde, Jordi, Montaner, Joan, Slowik, Agnieszka, Woo, Daniel, Hofman, Albert, Koudstaal, Peter J, Portegies, Marileen L P, Uitterlinden, André G, Ford, Ian, Jukema, J Wouter, Stott, David J, Allen, Norrina B, Johnson, Andrew D, De Jager, Philip L, White, Charles C, Markus, Marcello Ricardo Paulista, Schminke, Ulf, Boncoraglio, Giorgio B, Clarke, Robert, Kamatani, Yoichiro, Dallongeville, Jean, Rotter, Jerome I, Nalls, Michael A, Griswold, Michael E, Knopman, David S, Windham, B Gwen, Beiser, Alexa, Vartiainen, Erkki, French, Curtis R, Pastinen, Tomi, Gudnason, Vilmundur, Kurth, Tobias, Harris, Tamara B, Rich, Stephen S, deStefano, Anita L, Rosand, Jonathan, Mosley, Thomas H, Ingelsson, Erik, van Duijn, Cornelia M, Tzourio, Christophe, Rexrode, Kathryn M, Lehmann, Ordan J, Launer, Lenore J, Carlsson, Peter, Chasman, Daniel I, Childs, Sarah J, Seshadri, Sudha, Debette, Stéphanie

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Genetic legacy of ancient hunter-gatherer Jomon in Japanese populations von Yamamoto, Kenichi, Namba, Shinichi, Sonehara, Kyuto, Suzuki, Ken, Sakaue, Saori, Cooke, Niall P., Higashiue, Shinichi, Kobayashi, Shuzo, Afuso, Hisaaki, Matsuura, Kosho, Mitsumoto, Yojiro, Fujita, Yasuhiko, Tokuda, Torao, Matsuda, Koichi, Gakuhari, Takashi, Yamauchi, Toshimasa, Kadowaki, Takashi, Nakagome, Shigeki, Okada, Yukinori

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Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss von Sonehara, Kyuto, Yano, Yoshitaka, Naito, Tatsuhiko, Goto, Shinobu, Yoshihara, Hiroyuki, Otani, Takahiro, Ozawa, Fumiko, Kitaori, Tamao, Matsuda, Koichi, Nishiyama, Takashi, Okada, Yukinori, Sugiura-Ogasawara, Mayumi

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Use of Viral Load as a Surrogate Marker in Clinical Studies of Cytomegalovirus in Solid Organ Transplantation: A Systematic Review and Meta-analysis von Natori, Yoichiro, Alghamdi, Ali, Tazari, Mahmood, Miller, Veronica, Husain, Shahid, Komatsu, Takashi, Griffiths, Paul, Ljungman, Per, Orchanian-Cheff, Ani, Kumar, Deepali, Humar, Atul

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Real-world analysis of apalutamide-associated skin adverse events in Japanese patients with advanced prostate cancer: a multi-institutional study in the Chu-shikoku Japan Urologica... von Tohi, Yoichiro, Kato, Takuma, Fukuhara, Hideo, Kobayashi, Keita, Ohira, Shin, Ikeda, Kenichiro, Daizumoto, Kei, Katayama, Satoshi, Shimizu, Ryutaro, Nishimura, Kenichi, Nagami, Taichi, Hayashida, Yushi, Hirama, Hiromi, Takamoto, Atsushi, Dainichi, Teruki, Sugimoto, Mikio

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Development of Ubiquitous On-Demand Study Support Environment for Nursing Students von Majima, Yukie, Nakamura, Yumiko, Maekawa, Yasuko, So, Yoichiro

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ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk von Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K, Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J, Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S, Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D Gareth R, Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B, González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N A, Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L, Nevanlinna, Heli, Olson, Janet E, Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E, Rosseel, Toon, Ruddy, Kathryn J, Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E, Trentham-Dietz, Amy, Vachon, Celine M, Volk, Alexander E, Weber-Lassalle, Nana, Weitzel, Jeffrey N, Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B, Vega, Ana, Rossing, Maria

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