Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer von Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, R. Brooks, Hay, Nissim

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Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase von Padyana, Anil K., Gross, Stefan, Jin, Lei, Cianchetta, Giovanni, Narayanaswamy, Rohini, Wang, Feng, Wang, Rui, Fang, Cheng, Lv, Xiaobing, Biller, Scott A., Dang, Lenny, Mahoney, Christopher E., Nagaraja, Nelamangala, Pirman, David, Sui, Zhihua, Popovici-Muller, Janeta, Smolen, Gromoslaw A.

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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway von Zhang, Jianmin, Ji, Jun-Yuan, Yu, Min, Overholtzer, Michael, Smolen, Gromoslaw A., Wang, Rebecca, Brugge, Joan S., Dyson, Nicholas J., Haber, Daniel A.

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Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway von Zhang, Jianmin, Smolen, Gromoslaw A, Haber, Daniel A

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Transforming Properties of YAP, a Candidate Oncogene on the Chromosome 11q22 Amplicon von Overholtzer, Michael, Zhang, Jianmin, Smolen, Gromoslaw A., Muir, Beth, Li, Wenmei, Sgroi, Dennis C., Deng, Chu-Xia, Brugge, Joan S., Haber, Daniel A.

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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition von Mahoney, Christopher E., Pirman, David, Chubukov, Victor, Sleger, Taryn, Hayes, Sebastian, Fan, Zi Peng, Allen, Eric L., Chen, Ying, Huang, Lingling, Liu, Meina, Zhang, Yingjia, McDonald, Gabrielle, Narayanaswamy, Rohini, Choe, Sung, Chen, Yue, Gross, Stefan, Cianchetta, Giovanni, Padyana, Anil K., Murray, Stuart, Liu, Wei, Marks, Kevin M., Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Nagaraja, Nelamangala, Biller, Scott A., Roddy, Thomas, Popovici-Muller, Janeta, Smolen, Gromoslaw A.

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Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH von Allen, Eric L., Ulanet, Danielle B., Pirman, David, Mahoney, Christopher E., Coco, John, Si, Yaguang, Chen, Ying, Huang, Lingling, Ren, Jinmin, Choe, Sung, Clasquin, Michelle F., Artin, Erin, Fan, Zi Peng, Cianchetta, Giovanni, Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Smolen, Gromoslaw A.

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Rational design of a ligand-controlled protein conformational switch von Dagliyan, Onur, Shirvanyants, David, Karginov, Andrei V., Ding, Feng, Fee, Lanette, Chandrasekaran, Srinivas N., Freisinger, Christina M., Smolen, Gromoslaw A., Huttenlocher, Anna, Hahn, Klaus M., Dokholyan, Nikolay V.

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Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1 von Javaid, Sarah, Zhang, Jianmin, Anderssen, Endre, Black, Josh C., Wittner, Ben S., Tajima, Ken, Ting, David T., Smolen, Gromoslaw A., Zubrowski, Matthew, Desai, Rushil, Maheswaran, Shyamala, Ramaswamy, Sridhar, Whetstine, Johnathan R., Haber, Daniel A.

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Amplification of MET May Identify a Subset of Cancers with Extreme Sensitivity to the Selective Tyrosine Kinase Inhibitor PHA-665752 von Smolen, Gromoslaw A., Sordella, Raffaella, Muir, Beth, Mohapatra, Gayatry, Barmettler, Anne, Archibald, Heidi, Kim, Woo J., Okimoto, Ross A., Bell, Daphne W., Sgroi, Dennis C., Christensen, James G., Settleman, Jeffrey, Haber, Daniel A.

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A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2 von Chan, Barden, Clasquin, Michelle, Smolen, Gromoslaw A, Histen, Gavin, Powe, Josh, Chen, Yue, Lin, Zhizhong, Lu, Chenming, Liu, Yan, Cang, Yong, Yan, Zhonghua, Xia, Yuanfeng, Thompson, Ryan, Singleton, Chris, Dorsch, Marion, Silverman, Lee, Su, Shin-San Michael, Freeze, Hudson H, Jin, Shengfang

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A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression von Yu, Min, Smolen, Gromoslaw A, Zhang, Jianmin, Wittner, Ben, Schott, Benjamin J, Brachtel, Elena, Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A

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Arabidopsis ATR1 Myb transcription factor controls indolic glucosinolate homeostasis von Celenza, J.L, Quiel, J.A, Smolen, G.A, Merrikh, H, Silvestro, A.R, Normanly, J, Bender, J

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MAPK7 Regulates EMT Features and Modulates the Generation of CTCs von Javaid, Sarah, Zhang, Jianmin, Smolen, Gromoslaw A, Yu, Min, Wittner, Ben S, Singh, Anurag, Arora, Kshitij S, Madden, Marissa W, Desai, Rushil, Zubrowski, Matthew J, Schott, Benjamin J, Ting, David T, Stott, Shannon L, Toner, Mehmet, Maheswaran, Shyamala, Shioda, Toshi, Ramaswamy, Sridhar, Haber, Daniel A

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A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration von Smolen, Gromoslaw A, Zhang, Jianmin, Zubrowski, Matthew J, Edelman, Elena J, Luo, Biao, Yu, Min, Ng, Lydia W, Scherber, Cally M, Schott, Benjamin J, Ramaswamy, Sridhar, Irimia, Daniel, Root, David E, Haber, Daniel A

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Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites von Diederichs, Sven, Jung, Stephanie, Rothenberg, S. Michael, Smolen, Gromoslaw A, Mlody, Barbara G, Haber, Daniel A

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Functional genomic landscape of cancer-intrinsic evasion of killing by T cells von Lawson, Keith A., Sousa, Cristovão M., Zhang, Xiaoyu, Kim, Eiru, Akthar, Rummy, Caumanns, Joseph J., Yao, Yuxi, Mikolajewicz, Nicholas, Ross, Catherine, Brown, Kevin R., Zid, Abdelrahman Abou, Fan, Zi Peng, Hui, Shirley, Krall, Jordan A., Simons, Donald M., Slater, Chloe J., De Jesus, Victor, Tang, Lujia, Singh, Richa, Goldford, Joshua E., Martin, Sarah, Huang, Qian, Francis, Elizabeth A., Habsid, Andrea, Climie, Ryan, Tieu, David, Wei, Jiarun, Li, Ren, Tong, Amy Hin Yan, Aregger, Michael, Chan, Katherine S., Han, Hong, Wang, Xiaowei, Mero, Patricia, Brumell, John H., Finelli, Antonio, Ailles, Laurie, Bader, Gary, Smolen, Gromoslaw A., Kingsbury, Gillian A., Hart, Traver, Kung, Charles, Moffat, Jason

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Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor von Li, Hongjie, Smolen, Gromoslaw A, Beers, Lisa F, Xia, Li, Gerald, William, Wang, Joanne, Haber, Daniel A, Lee, Sean Bong

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Preclinical toxicology profile of squalene epoxidase inhibitors von Nagaraja, Raj, Olaharski, Andrew, Narayanaswamy, Rohini, Mahoney, Christopher, Pirman, David, Gross, Stefan, Roddy, Thomas P., Popovici-Muller, Janeta, Smolen, Gromoslaw A., Silverman, Lee

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Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas von Remacha, Laura, Pirman, David, Mahoney, Christopher E., Coloma, Javier, Calsina, Bruna, Currás-Freixes, Maria, Letón, Rocío, Torres-Pérez, Rafael, Richter, Susan, Pita, Guillermo, Herráez, Belén, Cianchetta, Giovanni, Honrado, Emiliano, Maestre, Lorena, Urioste, Miguel, Aller, Javier, García-Uriarte, Óscar, Gálvez, María Ángeles, Luque, Raúl M., Lahera, Marcos, Moreno-Rengel, Cristina, Eisenhofer, Graeme, Montero-Conde, Cristina, Rodríguez-Antona, Cristina, Llorca, Óscar, Smolen, Gromoslaw A., Robledo, Mercedes, Cascón, Alberto

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