The Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals von Schlingemann, Joerg, Burns, Michael J., Ponting, David J., Martins Avila, Carolina, Romero, Naiffer E., Jaywant, Mrunal A., Smith, Graham F., Ashworth, Ian W., Simon, Stephanie, Saal, Christoph, Wilk, Andrzej

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry von Rizvi, Noreen F, Howe, John A, Nahvi, Ali, Klein, Daniel J, Fischmann, Thierry O, Kim, Hai-Young, McCoy, Mark A, Walker, Scott S, Hruza, Alan, Richards, Matthew P, Chamberlin, Chad, Saradjian, Peter, Butko, Margaret T, Mercado, Gabriel, Burchard, Julja, Strickland, Corey, Dandliker, Peter J, Smith, Graham F, Nickbarg, Elliott B

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Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database von Wright, Peter S.R., Smith, Graham F., Briggs, Katharine A., Thomas, Robert, Maglennon, Gareth, Mikulskis, Paulius, Chapman, Melissa, Greene, Nigel, Phillips, Benjamin U., Bender, Andreas

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Artificial Intelligence in Drug Safety and Metabolism von Smith, Graham F.

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The 1997 event in the Crab pulsar revisited von Graham Smith, F., Lyne, A. G., Jordan, C.

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Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications von Lim, Jongwon, Altman, Michael D., Baker, James, Brubaker, Jason D., Chen, Hongmin, Chen, Yiping, Kleinschek, Melanie A., Li, Chaomin, Liu, Duan, Maclean, John K.F., Mulrooney, Erin F., Presland, Jeremy, Rakhilina, Larissa, Smith, Graham F., Yang, Ruojing

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RNA as a small molecule druggable target von Rizvi, Noreen F., Smith, Graham F.

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45 years of rotation of the Crab pulsar von Lyne, A G, Jordan, C A, Graham-Smith, F, Espinoza, C M, Stappers, B W, Weltevrede, P

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Targeting RNA with small molecules-A safety perspective von Lightfoot, Helen L, Smith, Graham F

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Targeting Xist with compounds that disrupt RNA structure and X inactivation von Aguilar, Rodrigo, Spencer, Kerrie B., Kesner, Barry, Rizvi, Noreen F., Badmalia, Maulik D., Mrozowich, Tyler, Mortison, Jonathan D., Rivera, Carlos, Smith, Graham F., Burchard, Julja, Dandliker, Peter J., Patel, Trushar R., Nickbarg, Elliott B., Lee, Jeannie T.

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Mode switching and subpulse drifting in PSR B0826-34 von Esamdin, A., Lyne, A. G., Graham-Smith, F., Kramer, M., Manchester, R. N., Wu, X.

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Prediction of In Vivo Pharmacokinetic Parameters and Time–Exposure Curves in Rats Using Machine Learning from the Chemical Structure von Obrezanova, Olga, Martinsson, Anton, Whitehead, Tom, Mahmoud, Samar, Bender, Andreas, Miljković, Filip, Grabowski, Piotr, Irwin, Ben, Oprisiu, Ioana, Conduit, Gareth, Segall, Matthew, Smith, Graham F, Williamson, Beth, Winiwarter, Susanne, Greene, Nigel

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Promiscuity of in Vitro Secondary Pharmacology Assays and Implications for Lead Optimization Strategies von Brown, Dean G, Smith, Graham F, Wobst, Heike J

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Prediction of inotropic effect based on calcium transients in human iPSC-derived cardiomyocytes and machine learning von Yang, Hongbin, Obrezanova, Olga, Pointon, Amy, Stebbeds, Will, Francis, Jo, Beattie, Kylie A., Clements, Peter, Harvey, James S., Smith, Graham F., Bender, Andreas

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Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency von Snodin, David J., Trejo-Martin, Alejandra, Ponting, David J., Smith, Graham F., Czich, Andreas, Cross, Kevin, Custer, Laura, Elloway, Joanne, Greene, Nigel, Kalgutkar, Amit S., Stalford, Susanne A., Tennant, Rachael E., Vock, Esther, Zalewski, Adam, Ziegler, Verena, Dobo, Krista L.

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Synthesis of Cyclic Peptidomimetics via a Pd-Catalyzed Macroamination Reaction von Hopkins, Brett A, Smith, Graham F, Sciammetta, Nunzio

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Revisiting the Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals von Burns, Michael J, Ponting, David J, Foster, Robert S, Thornton, Benjamin P, Romero, Naiffer E, Smith, Graham F, Ashworth, Ian W, Teasdale, Andrew, Simon, Stephanie, Schlingemann, Joerg

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Statistical analysis of preclinical inter-species concordance of histopathological findings in the eTOX database von Wright, Peter S.R., Briggs, Katharine A., Thomas, Robert, Smith, Graham F., Maglennon, Gareth, Mikulskis, Paulius, Chapman, Melissa, Greene, Nigel, Phillips, Benjamin U., Bender, Andreas

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Optimization of an Imidazo[1,2‑a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy von McCoull, William, Boyd, Scott, Brown, Martin R, Coen, Muireann, Collingwood, Olga, Davies, Nichola L, Doherty, Ann, Fairley, Gary, Goldberg, Kristin, Hardaker, Elizabeth, He, Guang, Hennessy, Edward J, Hopcroft, Philip, Hodgson, George, Jackson, Anne, Jiang, Xiefeng, Karmokar, Ankur, Lainé, Anne-Laure, Lindsay, Nicola, Mao, Yumeng, Markandu, Roshini, McMurray, Lindsay, McLean, Neville, Mooney, Lorraine, Musgrove, Helen, Nissink, J. Willem M, Pflug, Alexander, Reddy, Venkatesh Pilla, Rawlins, Philip B, Rivers, Emma, Schimpl, Marianne, Smith, Graham F, Tentarelli, Sharon, Travers, Jon, Troup, Robert I, Walton, Josephine, Wang, Cheng, Wilkinson, Stephen, Williamson, Beth, Winter-Holt, Jon, Yang, Dejian, Zheng, Yuting, Zhu, Qianxiu, Smith, Paul D

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Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space von Rizvi, Noreen F., Santa Maria, John P., Nahvi, Ali, Klappenbach, Joel, Klein, Daniel J., Curran, Patrick J., Richards, Matthew P., Chamberlin, Chad, Saradjian, Peter, Burchard, Julja, Aguilar, Rodrigo, Lee, Jeannie T., Dandliker, Peter J., Smith, Graham F., Kutchukian, Peter, Nickbarg, Elliott B.

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