PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity von Gato-Cañas, Maria, Zuazo, Miren, Arasanz, Hugo, Ibañez-Vea, Maria, Lorenzo, Laura, Fernandez-Hinojal, Gonzalo, Vera, Ruth, Smerdou, Cristian, Martisova, Eva, Arozarena, Imanol, Wellbrock, Claudia, Llopiz, Diana, Ruiz, Marta, Sarobe, Pablo, Breckpot, Karine, Kochan, Grazyna, Escors, David

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Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication von Carnero, Elena, Barriocanal, Marina, Prior, Celia, Pablo Unfried, Juan, Segura, Victor, Guruceaga, Elizabeth, Enguita, Mónica, Smerdou, Cristian, Gastaminza, Pablo, Fortes, Puri

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Gene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model von Weber, Nicholas D., Odriozola, Leticia, Martínez-García, Javier, Ferrer, Veronica, Douar, Anne, Bénichou, Bernard, González-Aseguinolaza, Gloria, Smerdou, Cristian

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Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19 von Silva-Pilipich, Noelia, Beloki, Uxue, Salaberry, Laura, Smerdou, Cristian

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Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma von Casales, Erkuden, Martisova, Eva, Villanueva, Helena, de Cerio, Ascensión López Díaz, Inoges, Susana, Silva-Pilipich, Noelia, Ballesteros-Briones, María Cristina, Aranda, Alejandro, Bezunartea, Jaione, Bendandi, Maurizio, Pastor, Fernando, Smerdou, Cristian

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DNA electroporation in a vacuum: A “shocking” innovation for vaccines von Silva-Pilipich, Noelia, Lasarte-Cía, Aritz, Lasarte, Juan José, Smerdou, Cristian

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A Small Virus to Deliver Small Antibodies: New Targeted Therapies Based on AAV Delivery of Nanobodies von Silva-Pilipich, Noelia, Smerdou, Cristian, Vanrell, Lucía

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Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer von Silva-Pilipich, Noelia, Lasarte-Cía, Aritz, Lozano, Teresa, Martín-Otal, Celia, Lasarte, Juan José, Smerdou, Cristian

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Cell-specific delivery of CRISPR-Cas9 with pseudotyped lentiviral particles: Just change the envelope von Covo-Vergara, Ángela, Salaberry, Laura, Silva-Pilipich, Noelia, Hervas-Stubbs, Sandra, Smerdou, Cristian

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Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer von Aparicio, Belén, Repáraz, David, Ruiz, Marta, Llopiz, Diana, Silva, Leyre, Vercher, Enric, Theunissen, Patrick, Tamayo, Ibon, Smerdou, Cristian, Igea, Ana, Santisteban, Marta, Gónzalez-Deza, Cristina, Lasarte, Juan J., Hervás-Stubbs, Sandra, Sarobe, Pablo

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Adenovirus-Mediated Inducible Expression of a PD-L1 Blocking Antibody in Combination with Macrophage Depletion Improves Survival in a Mouse Model of Peritoneal Carcinomatosis von Buñuales, Maria, Ballesteros-Briones, Maria Cristina, Gonzalez-Aparicio, Manuela, Hervas-Stubbs, Sandra, Martisova, Eva, Mancheño, Uxua, Ricobaraza, Ana, Lumbreras, Sara, Smerdou, Cristian, Hernandez-Alcoceba, Ruben

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A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector von Martínez-García, Javier, Molina, Manuela, Odriozola, Leticia, Molina, Angie, González-Aseguinolaza, Gloria, Weber, Nicholas D, Smerdou, Cristian

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Photodynamic nasal SARS-CoV-2 decolonization shortens infectivity and influences specific T-Cell responses von Fernandez-Montero, Alejandro, Zuaznabar, Jon, Pina-Sanchez, Manuel, Maestro, Sheila, Martin-Navarro, Loreto, Muñoz-Rodríguez, Natalia, Olagüe, Cristina, Pastrana, Marta, Martínez-Fernández, Maria, Camps, Gracian, Rodriguez, Jose Antonio, Marchese, Francesco P, Zazpe, Jon, Pozuelo, Marta, Del Pozo, José Luis, Quiroga, Jorge, Pineda-Lucena, Antonio, Reina, Gabriel, Kolenda, Jack, Moreno-Galarraga, Laura, Gonzalez-Aseguinolaza, Gloria, Rua, Marta, Smerdou, Cristian, Carmona-Torre, Francisco, Argemi, Josepmaria

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Gene Therapy for Acquired and Genetic Cholestasis von Martínez-García, Javier, Molina, Angie, González-Aseguinolaza, Gloria, Weber, Nicholas D., Smerdou, Cristian

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741 Expression of galectin-3 inhibitors from a self-replicating RNA vector as treatment for pediatric osteasarcoma von Cañete, Guillermo Herrador, Zalacain, Marta, Labiano, Sara, Martinez, Javier, Smerdou, Cristian, Alonso, Marta

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Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas von Rodriguez-Madoz, Juan R, Zabala, Maider, Alfaro, Maite, Prieto, Jesus, Kramer, M Gabriela, Smerdou, Cristian

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Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity von Rubio-Pérez, Laura, Frago, Susana, Compte, Marta, Navarro, Rocío, Harwood, Seandean L, Lázaro-Gorines, Rodrigo, Gómez-Rosel, Marina, Hangiu, Oana, Silva-Pilipich, Noelia, Vanrell, Lucía, Smerdou, Cristian, Álvarez-Vallina, Luis

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Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without Toxicity von Silva-Pilipich, Noelia, Martisova, Eva, Ballesteros-Briones, María Cristina, Hervas-Stubbs, Sandra, Casares, Noelia, González-Sapienza, Gualberto, Smerdou, Cristian, Vanrell, Lucia

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Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses von Aparicio, Belén, Casares, Noelia, Egea, Josune, Ruiz, Marta, Llopiz, Diana, Maestro, Sheila, Olagüe, Cristina, González-Aseguinolaza, Gloria, Smerdou, Cristian, López-Díaz de Cerio, Ascensión, Inogés, Susana, Prósper, Felipe, Yuste, José R., Carmona-Torre, Francisco, Reina, Gabriel, Lasarte, Juan J., Sarobe, Pablo

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Rapid SARS-CoV-2 disinfection on distant surfaces with UV-C: The inactivation is affected by the type of material von Olagüe, Cristina, Mitxelena-Iribarren, Oihane, Sierra-García, J.Enrique, Rodriguez-Merino, Fernando, Maestro, Sheila, Pérez-Lorenzo, Eva, Guillen-Grima, Francisco, González-Aseguinolaza, Gloria, Arana, Sergio, Smerdou, Cristian

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