Clinical development of metabolic inhibitors for oncology von Lemberg, Kathryn M, Gori, Sadakatali S, Tsukamoto, Takashi, Rais, Rana, Slusher, Barbara S

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Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network von Skácel, Jan, Slusher, Barbara S, Tsukamoto, Takashi

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Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion von Leone, Robert D, Zhao, Liang, Englert, Judson M, Sun, Im-Meng, Oh, Min-Hee, Sun, Im-Hong, Arwood, Matthew L, Bettencourt, Ian A, Patel, Chirag H, Wen, Jiayu, Tam, Ada, Blosser, Richard L, Prchalova, Eva, Alt, Jesse, Rais, Rana, Slusher, Barbara S, Powell, Jonathan D

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Pharmacological mechanisms of 5-HT3 and tachykinin NK1 receptor antagonism to prevent chemotherapy-induced nausea and vomiting von Rojas, Camilo, Slusher, Barbara S.

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Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis von Dixon, Scott J, Patel, Darpan N, Welsch, Matthew, Skouta, Rachid, Lee, Eric D, Hayano, Miki, Thomas, Ajit G, Gleason, Caroline E, Tatonetti, Nicholas P, Slusher, Barbara S, Stockwell, Brent R

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Preventing Allograft Rejection by Targeting Immune Metabolism von Lee, Chen-Fang, Lo, Ying-Chun, Cheng, Chih-Hsien, Furtmüller, Georg J., Oh, Byoungchol, Andrade-Oliveira, Vinicius, Thomas, Ajit G., Bowman, Caitlyn E., Slusher, Barbara S., Wolfgang, Michael J., Brandacher, Gerald, Powell, Jonathan D.

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Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells von Le, Anne, Lane, Andrew N., Hamaker, Max, Bose, Sminu, Gouw, Arvin, Barbi, Joseph, Tsukamoto, Takashi, Rojas, Camilio J., Slusher, Barbara S., Zhang, Haixia, Zimmerman, Lisa J., Liebler, Daniel C., Slebos, Robbert J.C., Lorkiewicz, Pawel K., Higashi, Richard M., Fan, Teresa W.M., Dang, Chi V.

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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis von Xiang, Yan, Stine, Zachary E, Xia, Jinsong, Lu, Yunqi, O'Connor, Roddy S, Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Thomas, Ajit G, Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S, Zhuo, Jingli, Ooi, London L, Lee, Caroline G L, Mancuso, Anthony, McCallion, Andrew S, Le, Anne, Milone, Michael C, Rayport, Stephen, Felsher, Dean W, Dang, Chi V

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Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects von Krečmerová, Marcela, Majer, Pavel, Rais, Rana, Slusher, Barbara S

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Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties von Figuera-Losada, Mariana, Stathis, Marigo, Dorskind, Joelle M, Thomas, Ajit G, Bandaru, Veera Venkata Ratnam, Yoo, Seung-Wan, Westwood, Nicholas J, Rogers, Graeme W, McArthur, Justin C, Haughey, Norman J, Slusher, Barbara S, Rojas, Camilo

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Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain von Zhang, Zhi, Bassam, Bassam, Thomas, Ajit G, Williams, Monica, Liu, Jinhuan, Nance, Elizabeth, Rojas, Camilo, Slusher, Barbara S, Kannan, Sujatha

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Neuronal deletion of nSMase2 reduces the production of Aβ and directly protects neurons von Tohumeken, Sehmus, Deme, Pragney, Yoo, Seung Wan, Gupta, Sujasha, Rais, Rana, Slusher, Barbara S., Haughey, Norman J.

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Intranasal insulin therapy reverses hippocampal dendritic injury and cognitive impairment in a model of HIV-associated neurocognitive disorders in EcoHIV-infected mice von Kim, Boe-Hyun, Kelschenbach, Jennifer, Borjabad, Alejandra, Hadas, Eran, He, Hongxia, Potash, Mary Jane, Nedelcovych, Michael T, Rais, Rana, Haughey, Norman J, McArthur, Justin C, Slusher, Barbara S, Volsky, David J

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Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms von Arab, Tanina, Mallick, Emily R., Huang, Yiyao, Dong, Liang, Liao, Zhaohao, Zhao, Zezhou, Gololobova, Olesia, Smith, Barbara, Haughey, Norman J., Pienta, Kenneth J., Slusher, Barbara S., Tarwater, Patrick M., Tosar, Juan Pablo, Zivkovic, Angela M., Vreeland, Wyatt N., Paulaitis, Michael E., Witwer, Kenneth W.

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Inhibition of substance P-mediated responses in NG108-15 cells by netupitant and palonosetron exhibit synergistic effects von Stathis, Marigo, Pietra, Claudio, Rojas, Camilo, Slusher, Barbara S.

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GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice von Su, Yu, Huang, Meixiang, Thomas, Ajit G, Maragakis, John, Huizar, Kaitlyn D J, Zheng, Yuxin, Wu, Ying, Farah, Mohamed H, Slusher, Barbara S

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Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis von Parveen, Sadiya, Shen, Jessica, Lun, Shichun, Zhao, Liang, Alt, Jesse, Koleske, Benjamin, Leone, Robert D., Rais, Rana, Powell, Jonathan D., Murphy, John R., Slusher, Barbara S., Bishai, William R.

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Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR‐Driven Lung Cancer von Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Montuenga, Luis M., Wang, Yian, Slusher, Barbara S., You, Ming

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Valley of death: A proposal to build a “translational bridge” for the next generation von Gamo, Nao J., Birknow, Michelle R., Sullivan, Danielle, Kondo, Mari A., Horiuchi, Yasue, Sakurai, Takeshi, Slusher, Barbara S., Sawa, Akira

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MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice von Riggle, Brittany A., Sinharay, Sanhita, Schreiber-Stainthorp, William, Munasinghe, Jeeva P., Maric, Dragan, Prchalova, Eva, Slusher, Barbara S., Powell, Jonathan D., Miller, Louis H., Pierce, Susan K., Hammoud, Dima A.

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