Synthesis of Acyl Phosphoramidates Employing a Modified Staudinger Reaction von Currie, Iain, Sleebs, Brad E

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Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery von Duffy, Sandra, Sykes, Melissa L, Jones, Amy J, Shelper, Todd B, Simpson, Moana, Lang, Rebecca, Poulsen, Sally-Ann, Sleebs, Brad E, Avery, Vicky M

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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell von Gabriela, Mikha, Matthews, Kathryn M, Boshoven, Cas, Kouskousis, Betty, Jonsdottir, Thorey K, Bullen, Hayley E, Modak, Joyanta, Steer, David L, Sleebs, Brad E, Crabb, Brendan S, Koning-Ward, Tania F de, Gilson, Paul R

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Mitoxantrone, More than Just Another Topoisomerase II Poison von Evison, Benny J., Sleebs, Brad E., Watson, Keith G., Phillips, Don R., Cutts, Suzanne M.

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Chemo-proteomics in antimalarial target identification and engagement von Bailey, Brodie L, Nguyen, William, Cowman, Alan F, Sleebs, Brad E

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An appraisal of natural products active against parasitic nematodes of animals von Garcia-Bustos, Jose F, Sleebs, Brad E, Gasser, Robin B

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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites von Sleebs, Brad E, Lopaticki, Sash, Marapana, Danushka S, O'Neill, Matthew T, Rajasekaran, Pravin, Gazdik, Michelle, Günther, Svenja, Whitehead, Lachlan W, Lowes, Kym N, Barfod, Lea, Hviid, Lars, Shaw, Philip J, Hodder, Anthony N, Smith, Brian J, Cowman, Alan F, Boddey, Justin A

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle von Favuzza, Paola, de Lera Ruiz, Manuel, Thompson, Jennifer K., Triglia, Tony, Ngo, Anna, Steel, Ryan W.J., Vavrek, Marissa, Christensen, Janni, Healer, Julie, Boyce, Christopher, Guo, Zhuyan, Hu, Mengwei, Khan, Tanweer, Murgolo, Nicholas, Zhao, Lianyun, Penington, Jocelyn Sietsma, Reaksudsan, Kitsanapong, Jarman, Kate, Dietrich, Melanie H., Richardson, Lachlan, Guo, Kai-Yuan, Lopaticki, Sash, Tham, Wai-Hong, Rottmann, Matthias, Papenfuss, Tony, Robbins, Jonathan A., Boddey, Justin A., Sleebs, Brad E., Sabroux, Hélène Jousset, McCauley, John A., Olsen, David B., Cowman, Alan F.

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Late Stage Phosphotyrosine Mimetic Functionalization of Peptides Employing Metallaphotoredox Catalysis von Chen, Hao, Mao, Runyu, Brzozowski, Martin, Nguyen, Nghi H, Sleebs, Brad E

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The Development Process for Discovery and Clinical Advancement of Modern Antimalarials von Ashton, Trent D, Devine, Shane M, Möhrle, Jörg J, Laleu, Benoît, Burrows, Jeremy N, Charman, Susan A, Creek, Darren J, Sleebs, Brad E

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Structure-guided design of a selective BCL-XL inhibitor von Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, Paul, Kersten, Wilhelmus J A, Kulasegaram, Sanji, Moss, Rebecca M, Parisot, John P, Smith, Brian J, Street, Ian P, Yang, Hong, Huang, David C S, Watson, Keith G

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Role of Plasmepsin V in Export of Diverse Protein Families from the Plasmodium falciparum Exportome von Boddey, Justin A., Carvalho, Teresa G., Hodder, Anthony N., Sargeant, Tobias J., Sleebs, Brad E., Marapana, Danushka, Lopaticki, Sash, Nebl, Thomas, Cowman, Alan F.

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Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes von Hodder, Anthony N, Sleebs, Brad E, Czabotar, Peter E, Gazdik, Michelle, Xu, Yibin, O'Neill, Matthew T, Lopaticki, Sash, Nebl, Thomas, Triglia, Tony, Smith, Brian J, Lowes, Kym, Boddey, Justin A, Cowman, Alan F

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Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868 von Taki, Aya C., Wang, Tao, Nguyen, Nghi N., Ang, Ching-Seng, Leeming, Michael G., Nie, Shuai, Byrne, Joseph J., Young, Neil D., Zheng, Yuanting, Ma, Guangxu, Korhonen, Pasi K., Koehler, Anson V., Williamson, Nicholas A., Hofmann, Andreas, Chang, Bill C. H., Häberli, Cécile, Keiser, Jennifer, Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.

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Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds von Dans, Madeline G., Weiss, Greta E., Wilson, Danny W., Sleebs, Brad E., Crabb, Brendan S., de Koning-Ward, Tania F., Gilson, Paul R.

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A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity von Shanley, Harrison T, Taki, Aya C, Byrne, Joseph J, Nguyen, Nghi, Wells, Tim N C, Jabbar, Abdul, Sleebs, Brad E, Gasser, Robin B

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The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites von Looker, Oliver, Dans, Madeline G., Bullen, Hayley E., Sleebs, Brad E., Crabb, Brendan S., Gilson, Paul R.

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Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of Haemonchus contortus In Vitro von Herath, H M P Dilrukshi, Taki, Aya C, Nguyen, Nghi, Garcia-Bustos, José, Hofmann, Andreas, Wang, Tao, Ma, Guangxu, Chang, Bill C H, Jabbar, Abdul, Sleebs, Brad E, Gasser, Robin B

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Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes von Jennison, Charlie, Lucantoni, Leonardo, O’Neill, Matthew T., McConville, Robyn, Erickson, Sara M., Cowman, Alan F., Sleebs, Brad E., Avery, Vicky M., Boddey, Justin A.

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An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell von Coffey, Michael J, Sleebs, Brad E, Uboldi, Alessandro D, Garnham, Alexandra, Franco, Magdalena, Marino, Nicole D, Panas, Michael W, Ferguson, David Jp, Enciso, Marta, O'Neill, Matthew T, Lopaticki, Sash, Stewart, Rebecca J, Dewson, Grant, Smyth, Gordon K, Smith, Brian J, Masters, Seth L, Boothroyd, John C, Boddey, Justin A, Tonkin, Christopher J

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