Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance von Sully, Erin K, Malachowa, Natalia, Elmore, Bradley O, Alexander, Susan M, Femling, Jon K, Gray, Brian M, DeLeo, Frank R, Otto, Michael, Cheung, Ambrose L, Edwards, Bruce S, Sklar, Larry A, Horswill, Alexander R, Hall, Pamela R, Gresham, Hattie D

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Clioquinol: To harm or heal von Perez, Dominique R., Sklar, Larry A., Chigaev, Alexandre

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Pharos: Collating protein information to shed light on the druggable genome von Nguyen, Dac-Trung, Mathias, Stephen, Bologa, Cristian, Brunak, Soren, Fernandez, Nicolas, Gaulton, Anna, Hersey, Anne, Holmes, Jayme, Jensen, Lars Juhl, Karlsson, Anneli, Liu, Guixia, Ma'ayan, Avi, Mandava, Geetha, Mani, Subramani, Mehta, Saurabh, Overington, John, Patel, Juhee, Rouillard, Andrew D, Schürer, Stephan, Sheils, Timothy, Simeonov, Anton, Sklar, Larry A, Southall, Noel, Ursu, Oleg, Vidovic, Dusica, Waller, Anna, Yang, Jeremy, Jadhav, Ajit, Oprea, Tudor I, Guha, Rajarshi

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Unexplored therapeutic opportunities in the human genome von Oprea, Tudor I., Bologa, Cristian G., Brunak, Søren, Campbell, Allen, Gan, Gregory N., Gaulton, Anna, Gomez, Shawn M., Guha, Rajarshi, Hersey, Anne, Holmes, Jayme, Jadhav, Ajit, Jensen, Lars Juhl, Johnson, Gary L., Karlson, Anneli, Leach, Andrew R., Ma'ayan, Avi, Malovannaya, Anna, Mani, Subramani, Mathias, Stephen L., McManus, Michael T., Meehan, Terrence F., von Mering, Christian, Muthas, Daniel, Nguyen, Dac-Trung, Overington, John P., Papadatos, George, Qin, Jun, Reich, Christian, Roth, Bryan L., Schürer, Stephan C., Simeonov, Anton, Sklar, Larry A., Southall, Noel, Tomita, Susumu, Tudose, Ilinca, Ursu, Oleg, Vidović, Dušica, Waller, Anna, Westergaard, David, Yang, Jeremy J., Zahoránszky-Köhalmi, Gergely

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Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling von Revankar, Chetana M, Cimino, Daniel F, Sklar, Larry A, Arterburn, Jeffrey B, Prossnitz, Eric R

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Estrogen signaling through the transmembrane G protein-coupled receptor GPR30 von Prossnitz, Eric R, Arterburn, Jeffrey B, Smith, Harriet O, Oprea, Tudor I, Sklar, Larry A, Hathaway, Helen J

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GPR30 Expression Is Required for the Mineralocorticoid Receptor–Independent Rapid Vascular Effects of Aldosterone von Gros, Robert, Ding, Qingming, Sklar, Larry A, Prossnitz, Eric E, Arterburn, Jeffrey B, Chorazyczewski, Jozef, Feldman, Ross D

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Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity von Dennis, Megan K., Field, Angela S., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Bologa, Cristian G., Oprea, Tudor I., Yamaguchi, Yuri, Hayashi, Shin-Ichi, Sklar, Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.

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Flow Cytometry: Impact on Early Drug Discovery von Edwards, Bruce S., Sklar, Larry A.

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Best practices for managing and disseminating resources and outreach and evaluating the impact of the IDG Consortium von Vidović, Dušica, Waller, Anna, Holmes, Jayme, Sklar, Larry A., Schürer, Stephan C.

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R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis von Guo, Yuna, Kenney, S Ray, Muller, Carolyn Y, Adams, Sarah, Rutledge, Teresa, Romero, Elsa, Murray-Krezan, Cristina, Prekeris, Rytis, Sklar, Larry A, Hudson, Laurie G, Wandinger-Ness, Angela

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Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system von Brailoiu, Eugen, Dun, Siok L, Brailoiu, G Cristina, Mizuo, Keisuke, Sklar, Larry A, Oprea, Tudor I, Prossnitz, Eric R, Dun, Nae J

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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity von Perez, Dominique R., Sklar, Larry A., Chigaev, Alexandre, Matlawska-Wasowska, Ksenia

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Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases von Oprea, Tudor I, Sklar, Larry A, Agola, Jacob O, Guo, Yuna, Silberberg, Melina, Roxby, Joshua, Vestling, Anna, Romero, Elsa, Surviladze, Zurab, Murray-Krezan, Cristina, Waller, Anna, Ursu, Oleg, Hudson, Laurie G, Wandinger-Ness, Angela

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Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe von Hong, Lin, Kenney, S.Ray, Phillips, Genevieve K., Simpson, Denise, Schroeder, Chad E., Nöth, Julica, Romero, Elsa, Swanson, Scarlett, Waller, Anna, Strouse, J.Jacob, Carter, Mark, Chigaev, Alexandre, Ursu, Oleg, Oprea, Tudor, Hjelle, Brian, Golden, Jennifer E., Aubé, Jeffrey, Hudson, Laurie G., Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela

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GPR30: A G protein-coupled receptor for estrogen von Prossnitz, Eric R., Arterburn, Jeffrey B., Sklar, Larry A.

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Far away from the lamppost von Oprea, Tudor I, Jan, Lily, Johnson, Gary L, Roth, Bryan L, Ma'ayan, Avi, Schürer, Stephan, Shoichet, Brian K, Sklar, Larry A, McManus, Michael T

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A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs von Cao, Ziming, Garcia, Matthew J, Sklar, Larry A, Wandinger-Ness, Angela, Fan, Zhichao

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Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility von Thal, David M, Homan, Kristoff T, Chen, Jun, Wu, Emily K, Hinkle, Patricia M, Huang, Z. Maggie, Chuprun, J. Kurt, Song, Jianliang, Gao, Erhe, Cheung, Joseph Y, Sklar, Larry A, Koch, Walter J, Tesmer, John J.G

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In vivo effects of a GPR30 antagonist von Dennis, Megan K, Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K, Alcon, Sara N, Nayak, Tapan K, Bologa, Cristian G, Leitao, Andrei, Brailoiu, Eugen, Deliu, Elena, Dun, Nae J, Sklar, Larry A, Hathaway, Helen J, Arterburn, Jeffrey B, Oprea, Tudor I, Prossnitz, Eric R

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