Pharos: Collating protein information to shed light on the druggable genome von Nguyen, Dac-Trung, Mathias, Stephen, Bologa, Cristian, Brunak, Soren, Fernandez, Nicolas, Gaulton, Anna, Hersey, Anne, Holmes, Jayme, Jensen, Lars Juhl, Karlsson, Anneli, Liu, Guixia, Ma'ayan, Avi, Mandava, Geetha, Mani, Subramani, Mehta, Saurabh, Overington, John, Patel, Juhee, Rouillard, Andrew D, Schürer, Stephan, Sheils, Timothy, Simeonov, Anton, Sklar, Larry A, Southall, Noel, Ursu, Oleg, Vidovic, Dusica, Waller, Anna, Yang, Jeremy, Jadhav, Ajit, Oprea, Tudor I, Guha, Rajarshi

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Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance von Sully, Erin K, Malachowa, Natalia, Elmore, Bradley O, Alexander, Susan M, Femling, Jon K, Gray, Brian M, DeLeo, Frank R, Otto, Michael, Cheung, Ambrose L, Edwards, Bruce S, Sklar, Larry A, Horswill, Alexander R, Hall, Pamela R, Gresham, Hattie D

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Estrogen signaling through the transmembrane G protein-coupled receptor GPR30 von Prossnitz, Eric R, Arterburn, Jeffrey B, Smith, Harriet O, Oprea, Tudor I, Sklar, Larry A, Hathaway, Helen J

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GPR30 Expression Is Required for the Mineralocorticoid Receptor–Independent Rapid Vascular Effects of Aldosterone von Gros, Robert, Ding, Qingming, Sklar, Larry A, Prossnitz, Eric E, Arterburn, Jeffrey B, Chorazyczewski, Jozef, Feldman, Ross D

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Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling von Revankar, Chetana M, Cimino, Daniel F, Sklar, Larry A, Arterburn, Jeffrey B, Prossnitz, Eric R

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Flow Cytometry: Impact on Early Drug Discovery von Edwards, Bruce S., Sklar, Larry A.

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R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis von Guo, Yuna, Kenney, S Ray, Muller, Carolyn Y, Adams, Sarah, Rutledge, Teresa, Romero, Elsa, Murray-Krezan, Cristina, Prekeris, Rytis, Sklar, Larry A, Hudson, Laurie G, Wandinger-Ness, Angela

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Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system von Brailoiu, Eugen, Dun, Siok L, Brailoiu, G Cristina, Mizuo, Keisuke, Sklar, Larry A, Oprea, Tudor I, Prossnitz, Eric R, Dun, Nae J

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Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe von Hong, Lin, Kenney, S.Ray, Phillips, Genevieve K., Simpson, Denise, Schroeder, Chad E., Nöth, Julica, Romero, Elsa, Swanson, Scarlett, Waller, Anna, Strouse, J.Jacob, Carter, Mark, Chigaev, Alexandre, Ursu, Oleg, Oprea, Tudor, Hjelle, Brian, Golden, Jennifer E., Aubé, Jeffrey, Hudson, Laurie G., Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela

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Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility von Thal, David M, Homan, Kristoff T, Chen, Jun, Wu, Emily K, Hinkle, Patricia M, Huang, Z. Maggie, Chuprun, J. Kurt, Song, Jianliang, Gao, Erhe, Cheung, Joseph Y, Sklar, Larry A, Koch, Walter J, Tesmer, John J.G

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Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity von Dennis, Megan K., Field, Angela S., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Bologa, Cristian G., Oprea, Tudor I., Yamaguchi, Yuri, Hayashi, Shin-Ichi, Sklar, Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.

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The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida a... von HOLMES, Ann R, KENIYA, Mikhail V, IVNITSKI-STEELE, Irena, MONK, Brian C, LAMPING, Erwin, SKLAR, Larry A, CANNON, Richard D

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Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion von Chigaev, Alexandre, Sklar, Larry A

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Novel ABCG2 Antagonists Reverse Topotecan-Mediated Chemotherapeutic Resistance in Ovarian Carcinoma Xenografts von Ricci, Jerec W, Lovato, Debbie M, Severns, Virginia, Sklar, Larry A, Larson, Richard S

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Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases von Oprea, Tudor I, Sklar, Larry A, Agola, Jacob O, Guo, Yuna, Silberberg, Melina, Roxby, Joshua, Vestling, Anna, Romero, Elsa, Surviladze, Zurab, Murray-Krezan, Cristina, Waller, Anna, Ursu, Oleg, Hudson, Laurie G, Wandinger-Ness, Angela

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GPR30: a novel therapeutic target in estrogen-related disease von Prossnitz, Eric R, Sklar, Larry A, Oprea, Tudor I, Arterburn, Jeffrey B

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A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients von Guo, Yuna, Kenney, S Ray, Cook, Linda, Adams, Sarah F, Rutledge, Teresa, Romero, Elsa, Oprea, Tudor I, Sklar, Larry A, Bedrick, Edward, Wiggins, Charles L, Kang, Huining, Lomo, Lesley, Muller, Carolyn Y, Wandinger-Ness, Angela, Hudson, Laurie G

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The ins and outs of GPR30: A transmembrane estrogen receptor von Prossnitz, Eric R., Oprea, Tudor I., Sklar, Larry A., Arterburn, Jeffrey B.

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Far away from the lamppost von Oprea, Tudor I, Jan, Lily, Johnson, Gary L, Roth, Bryan L, Ma'ayan, Avi, Schürer, Stephan, Shoichet, Brian K, Sklar, Larry A, McManus, Michael T

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Suspension array technology: evolution of the flat-array paradigm von Nolan, John P, Sklar, Larry A

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