Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor‑γ (RORγ) Agonist for Use in Treating Cancer von Aicher, Thomas D, Van Huis, Chad A, Hurd, Alexander R, Skalitzky, Donald J, Taylor, Clarke B, Beleh, Omar M, Glick, Gary, Toogood, Peter L, Yang, Bing, Zheng, Tao, Huo, Changxin, Gao, Jie, Qiao, Chenxi, Tian, Xiaolong, Zhang, Junping, Demock, Kellie, Hao, Ling-Yang, Lesch, Charles A, Morgan, Rodney W, Moisan, Jacques, Wang, Yahong, Scatina, JoAnn, Paulos, Chrystal M, Zou, Weiping, Carter, Laura L, Hu, Xiao

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Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors von Skalitzky, Donald J, Marakovits, Joseph T, Maegley, Karen A, Ekker, Anne, Yu, Xiao-Hong, Hostomsky, Zdenek, Webber, Stephen E, Eastman, Brian W, Almassy, Robert, Li, Jianke, Curtin, Nicola J, Newell, David R, Calvert, A. Hilary, Griffin, Roger J, Golding, Bernard T

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Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, Part I: Transformation of selective pyrazolodiazepinone p... von Plummer, Mark S., Cornicelli, Joseph, Roark, Howard, Skalitzky, Donald J., Stankovic, Charles J., Bove, Susan, Pandit, Jayvardhan, Goodman, Annise, Hicks, James, Shahripour, Aurash, Beidler, David, Lu, Xiao Kang, Sanchez, Brian, Whitehead, Christopher, Sarver, Ron, Braden, Timothy, Gowan, Richard, Shen, Xi Qiang, Welch, Katherine, Ogden, Adam, Sadagopan, Nalini, Baum, Heidi, Miller, Howard, Banotai, Craig, Spessard, Cindy, Lightle, Sandra

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Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: Optimization studies and demonstration of in vivo... von Plummer, Mark S., Cornicelli, Joseph, Roark, Howard, Skalitzky, Donald J., Stankovic, Charles J., Bove, Susan, Pandit, Jayvardhan, Goodman, Annise, Hicks, James, Shahripour, Aurash, Beidler, David, Lu, Xiao Kang, Sanchez, Brian, Whitehead, Christopher, Sarver, Ron, Braden, Timothy, Gowan, Richard, Shen, Xi Qiang, Welch, Katherine, Ogden, Adam, Sadagopan, Nalini, Baum, Heidi, Miller, Howard, Banotai, Craig, Spessard, Cindy, Lightle, Sandra

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Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes:  Synthons for syn- and anti-1,3-Diols von RYCHNOVSKY, Scott D., BUCKMELTER, Alexandre J., DAHANUKAR, Vilas H., SKALITZKY, Donald J.

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Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors von White, Alex W., Curtin, Nicola J., Eastman, Brian W., Golding, Bernard T., Hostomsky, Zdenek, Kyle, Suzanne, Li, Jianke, Maegley, Karen A., Skalitzky, Donald J., Webber, Stephen E., Yu, Xiao-Hong, Griffin, Roger J.

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Optically pure 1,3-diols from (2R,4R)- and (2S,4S)-1,2:4,5-diepoxypentane von Rychnovsky, Scott D, Griesgraber, George, Zeller, Sam, Skalitzky, Donald J

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A practical preparation of .alpha.-alkoxylithium reagents: synthesis of syn or anti 1,3-diols von Rychnovsky, Scott D, Skalitzky, Donald J

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Design, synthesis, and biological evaluation of novel human 5′-deoxy-5′-methylthioadenosine phosphorylase (MTAP) substrates von Kung, Pei-Pei, Zehnder, Luke R., Meng, Jerry J., Kupchinsky, Stanley W., Skalitzky, Donald J., Johnson, M. Catherine, Maegley, Karen A., Ekker, Anne, Kuhn, Leslie A., Rose, Peter W., Bloom, Laura A.

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Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease von Johnson, Theodore O, Hua, Ye, Luu, Hiep T, Brown, Edward L, Chan, Fora, Chu, Shao Song, Dragovich, Peter S, Eastman, Brian W, Ferre, Rose Ann, Fuhrman, Shella A, Hendrickson, Thomas F, Maldonado, Fausto C, Matthews, David A, Meador, James W, Patick, Amy K, Reich, Siegfried H, Skalitzky, Donald J, Worland, Stephen T, Yang, Michelle, Zalman, Leora S

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Prins cyclization of 4-allyl-1,3-dioxanes prepared from 1,3-diol synthons. A rapid entry into functionalized tetrahydropyrans von Hu, Yueqing, Skalitzky, Donald J, Rychnovsky, Scott D

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Stereochemistry of the macrolactins von Rychnovsky, Scott D, Skalitzky, Donald J, Pathirana, Charles, Jensen, Paul R, Fenical, William

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Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes:  Synthons for syn- and a nti-1,3-Diols von Rychnovsky, Scott D, Buckmelter, Alexandre J, Dahanukar, Vilas H, Skalitzky, Donald J

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Stereoselective synthesis of syn-1,3-diol acetonides by reductive decyanation of cyanohydrins von Rychnovsky, Scott D, Zeller, Sam, Skalitzky, Donald J, Griesgraber, George

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Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes:  Synthons for syn- and anti-1,3-Diols von Rychnovsky, Scott D, Buckmelter, Alexandre J, Dahanukar, Vilas H, Skalitzky, Donald J

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The chemistry-medicine continuum: Synthetic, computer, spectroscopic and biological studies on new chemotherapeutic leads von Wender, Paul A., Martin-Cantalejo, Yolanda, Carpenter, Andrew J., Chiu, Anna, De Brabander, Jef, Harran, Patrick G., Jimenez, Juan-Miguel, Koehler, Michael F. T., Lippa, Blaise, Morrison, James A., Müller, Stephan G., Müller, Stephan N., Park, Cheol-Min, Shiozaki, Makoto, Siedenbiedel, Carsten, Skalitzky, Donald J., Tanaka, Masahiro, Irie, Kazuhiro

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Stereochemistry of alternating polyol chains: 13C NMR analysis of 1,3-diol acetonides von Rychnovsky, Scott D., Skalitzky, Donald J.

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ALKYLPYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF von SKALITZKY, Donald J, VAN HUIS, Chad A

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Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides von Dragovich, Peter S., Zhou, Ru, Skalitzky, Donald J., Fuhrman, Shella A., Patick, Amy K., Ford, Clifford E., Meador, James W., Worland, Stephen T.

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Alkylpyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof von Skalitzky, Donald J, Van Huis, Chad A

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