Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer von Gross, Matt I, Demo, Susan D, Dennison, Jennifer B, Chen, Lijing, Chernov-Rogan, Tania, Goyal, Bindu, Janes, Julie R, Laidig, Guy J, Lewis, Evan R, Li, Jim, Mackinnon, Andrew L, Parlati, Francesco, Rodriguez, Mirna L M, Shwonek, Peter J, Sjogren, Eric B, Stanton, Timothy F, Wang, Taotao, Yang, Jinfu, Zhao, Frances, Bennett, Mark K

Volltext

Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity von Li, Jim, Chen, Lijing, Billedeau, Roland J., Stanton, Timothy F., Chiang, John T. P., Lee, Clarissa C., Li, Weiqun, Steggerda, Susanne, Emberley, Ethan, Gross, Matthew, Bhupathi, Deepthi, Che, Xiaoying, Chen, Jason, Dang, Rosalyn, Huang, Tony, Ma, Yong, MacKinnon, Andrew, Makkouk, Amani, Marguier, Gisele, Neou, Silinda, Sotirovska, Natalija, Spurlock, Sandra, Zhang, Jing, Zhang, Winter, van Zandt, Michael, Yuan, Lin, Savoy, Jennifer, Parlati, Francesco, Sjogren, Eric B.

Volltext

Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrah... von Goldstein, David M, Soth, Michael, Gabriel, Tobias, Dewdney, Nolan, Kuglstatter, Andreas, Arzeno, Humberto, Chen, Jeffrey, Bingenheimer, William, Dalrymple, Stacie A, Dunn, James, Farrell, Robert, Frauchiger, Sandra, La Fargue, JoAnn, Ghate, Manjiri, Graves, Bradford, Hill, Ronald J, Li, Fujun, Litman, Renee, Loe, Brad, McIntosh, Joel, McWeeney, Daniel, Papp, Eva, Park, Jaehyeon, Reese, Harlan F, Roberts, Richard T, Rotstein, David, San Pablo, Bong, Sarma, Keshab, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca T, Sjogren, Eric B, Tan, Yunchou, Trejo, Alejandra, Welch, Mary, Weller, Paul, Wong, Brian R, Zecic, Hasim

Volltext

Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an Orally Bioavailable and Highly Selective Inhibitor of p38 Map... von Goldstein, David M, Alfredson, Tom, Bertrand, Jay, Browner, Michelle F, Clifford, Ken, Dalrymple, Stacie A, Dunn, James, Freire-Moar, Jose, Harris, Seth, Labadie, Sharada S, La Fargue, JoAnn, Lapierre, Jean Marc, Larrabee, Susan, Li, Fujun, Papp, Eva, McWeeney, Daniel, Ramesha, Chakk, Roberts, Rick, Rotstein, David, San Pablo, Bong, Sjogren, Eric B, So, On-Yee, Talamas, Francisco X, Tao, Will, Trejo, Alejandra, Villasenor, Armando, Welch, Mary, Welch, Teresa, Weller, Paul, Whiteley, Phyllis E, Young, Kelly, Zipfel, Sheila

Volltext

A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hit von Cushing, Timothy D., Baichwal, Vijay, Berry, Karen, Billedeau, Roland, Bordunov, Viola, Broka, Chris, Cardozo, Mario, Cheng, Peng, Clark, David, Dalrymple, Stacie, DeGraffenreid, Michael, Gill, Adrian, Hao, Xiaolin, Hawley, Ronald C., He, Xiao, Jaen, Juan C., Labadie, Sharada S., Labelle, Marc, Lehel, Csaba, Lu, Pu-Ping, McIntosh, Joel, Miao, Shichang, Parast, Camran, Shin, Youngsook, Sjogren, Eric B., Smith, Marie-Louise, Talamas, Francisco X., Tonn, George, Walker, Keith M., Walker, Nigel P.C., Wesche, Holger, Whitehead, Chris, Wright, Matt, Browner, Michelle F.

Volltext

A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs von Cushing, Timothy D., Baichwal, Vijay, Berry, Karen, Billedeau, Roland, Bordunov, Viola, Broka, Chris, Browner, Michelle F., Cardozo, Mario, Cheng, Peng, Clark, David, Dalrymple, Stacie, DeGraffenreid, Michael, Gill, Adrian, Hao, Xiaolin, Hawley, Ronald C., He, Xiao, Labadie, Sharada S., Labelle, Marc, Lehel, Csaba, Lu, Pu-Ping, McIntosh, Joel, Miao, Shichang, Parast, Camran, Shin, Youngsook, Sjogren, Eric B., Smith, Marie-Louise, Talamas, Francisco X., Tonn, George, Walker, Keith M., Walker, Nigel P.C., Wesche, Holger, Whitehead, Chris, Wright, Matt, Jaen, Juan C.

Volltext

Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8 H -pyrido[2,3- d ]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(te... von Goldstein, David M., Soth, Michael, Gabriel, Tobias, Dewdney, Nolan, Kuglstatter, Andreas, Arzeno, Humberto, Chen, Jeffrey, Bingenheimer, William, Dalrymple, Stacie A., Dunn, James, Farrell, Robert, Frauchiger, Sandra, La Fargue, JoAnn, Ghate, Manjiri, Graves, Bradford, Hill, Ronald J., Li, Fujun, Litman, Renee, Loe, Brad, McIntosh, Joel, McWeeney, Daniel, Papp, Eva, Park, Jaehyeon, Reese, Harlan F., Roberts, Richard T., Rotstein, David, San Pablo, Bong, Sarma, Keshab, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca T., Sjogren, Eric B., Tan, Yunchou, Trejo, Alejandra, Welch, Mary, Weller, Paul, Wong, Brian R., Zecic, Hasim

Volltext

N-Arylpiperazinyl-N‘-propylamino Derivatives of Heteroaryl Amides as Functional Uroselective α1-Adrenoceptor Antagonists von Elworthy, Todd R, Ford, Anthony P. D. W, Bantle, Gary W, Morgans, David J, Ozer, Rachel S, Palmer, Wylie S, Repke, David B, Romero, Magarita, Sandoval, Leticia, Sjogren, Eric B, Talamás, Francisco X, Vazquez, Alfredo, Wu, Helen, Arredondo, Nicolas F, Blue, David R, DeSousa, Andrea, Gross, Lisa M, Kava, M. Shannon, Lesnick, John D, Vimont, Rachel L, Williams, Timothy J, Zhu, Quan-Ming, Pfister, Jürg R, Clarke, David E

Volltext

Antitrichomonal activity of mesoionic thiazolo[3,2-a]pyridines von Walker, Keith A. M, Sjogren, Eric B, Matthews, Thomas R

Volltext

Aldol addition reactions of chiral crotonate imides von Evans, David A., Sjogren, Eric B., Bartroli, Javier, Dow, Robert L.

Volltext

The asymmetric synthesis of β-lactam antibiotics - III. Enantioselective synthesis of (+) PS-5 von Evans, David A, Sjogren, Eric B

Volltext

Synthesis and biological activity of a series of diaryl-substituted .alpha.-cyano-.beta.-hydroxypropenamides, a new class of anthelmintic agents von Sjogren, Eric B, Rider, Michael A, Nelson, Peter H, Bingham, Stanford, Poulton, Anthony L, Emanuel, Mark A, Komuniecki, Richard

Volltext

Composiciones y métodos para inhibir la actividad de la arginasa von SJOGREN, Eric B, VAN ZANDT, Michael, WHITEHOUSE, Darren, LI, Jim

Volltext bestellen

COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY von SJOGREN, Eric B, VAN ZANDT, Michael, WHITEHOUSE, Darren, LI, Jim

Volltext bestellen

COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY von SJOGREN, Eric, B, VAN ZANDT, Michael, WHITEHOUSE, Darren, LI, Jim

Volltext bestellen

Compositions and methods for inhibiting arginase activity von Whitehouse, Darren, Li, Jim, Van Zandt, Michael, Sjogren, Eric B

Volltext bestellen

Compositions and methods for inhibiting arginase activity von Whitehouse, Darren, Li, Jim, Van Zandt, Michael, Sjogren, Eric B

Volltext bestellen

Ectonucleotidase inhibitors and methods of use thereof von Li, Jim, Sjogren, Eric B, Chen, Lijing, Billedeau, Roland J

Volltext bestellen

Compositions and methods for inhibiting arginase activity von Whitehouse, Darren, Petersen, Lene Raunkjaer, Li, Jim, Stanton, Timothy F, Van Zandt, Michael, Sjogren, Eric B, Jagdmann, Jr., Gunnar E, Chen, Lijing, Billedeau, Roland J

Volltext bestellen

Compositions and methods for inhibiting arginase activity von Whitehouse, Darren, Li, Jim, Van Zandt, Michael, Sjogren, Eric B

Volltext bestellen