Genetic determinants of cellular addiction to DNA polymerase theta von Feng, Wanjuan, Simpson, Dennis A., Carvajal-Garcia, Juan, Price, Brandon A., Kumar, Rashmi J., Mose, Lisle E., Wood, Richard D., Rashid, Naim, Purvis, Jeremy E., Parker, Joel S., Ramsden, Dale A., Gupta, Gaorav P.

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A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability von Fagan-Solis, Katerina D., Simpson, Dennis A., Kumar, Rashmi J., Martelotto, Luciano G., Mose, Lisle E., Rashid, Naim U., Ho, Alice Y., Powell, Simon N., Wen, Y. Hannah, Parker, Joel S., Reis-Filho, Jorge S., Petrini, John H.J., Gupta, Gaorav P.

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Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells von Bower, Jacquelyn J., Vance, Leah D., Psioda, Matthew, Smith-Roe, Stephanie L., Simpson, Dennis A., Ibrahim, Joseph G., Hoadley, Katherine A., Perou, Charles M., Kaufmann, William K.

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An ATR- and Chk1-Dependent S Checkpoint Inhibits Replicon Initiation following UVC-Induced DNA Damage von Heffernan, Timothy P., Simpson, Dennis A., Frank, Alexandra R., Heinloth, Alexandra N., Paules, Richard S., Cordeiro-Stone, Marila, Kaufmann, William K.

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Targeting Non-homologous and Alternative End Joining Repair to Enhance Cancer Radiosensitivity von Feng, Wanjuan, Smith, Chelsea M., Simpson, Dennis A., Gupta, Gaorav P.

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Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts von Smith-Roe, Stephanie L., Patel, Shivani S., Simpson, Dennis A., Zhou, Ying Chun, Rao, Shangbang, Ibrahim, Joseph G., Kaiser-Rogers, Kathleen A., Cordeiro-Stone, Marila, Kaufmann, William K.

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Cdc7-Dbf4 and the Human S Checkpoint Response to UVC von Heffernan, Timothy P., Ünsal-Kaçmaz, Keziban, Heinloth, Alexandra N., Simpson, Dennis A., Paules, Richard S., Sancar, Aziz, Cordeiro-Stone, Marila, Kaufmann, William K.

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MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis von Cho, Min-Guk, Kumar, Rashmi J., Lin, Chien-Chu, Boyer, Joshua A., Shahir, Jamshaid A., Fagan-Solis, Katerina, Simpson, Dennis A., Fan, Cheng, Foster, Christine E., Goddard, Anna M., Lerner, Lynn M., Ellington, Simon W., Wang, Qinhong, Wang, Ying, Ho, Alice Y., Liu, Pengda, Perou, Charles M., Zhang, Qi, McGinty, Robert K., Purvis, Jeremy E., Gupta, Gaorav P.

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Revised genetic requirements for the decatenation G2 checkpoint: The role of ATM von Bower, Jacquelyn J., Zhou, Yingchun, Zhou, Tong, Simpson, Dennis A., Arlander, Sonnet J., Paules, Richard S., Cordeiro-Stone, Marila, Kaufmann, William K.

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Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53 von Chen, Bo, Simpson, Dennis A., Zhou, Yingchun, Mitra, Amritava, Mitchell, David L., Cordeiro-Stone, Marila, Kaufmann, William K.

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Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks von Feng, Wanjuan, Simpson, Dennis A, Cho, Jang-Eun, Carvajal-Garcia, Juan, Smith, Chelsea M, Headley, Kathryn M, Hathaway, Nate, Ramsden, Dale A, Gupta, Gaorav P

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Identification of Primary Transcriptional Regulation of Cell Cycle-Regulated Genes upon DNA Damage von Zhou, Tong, Chou, Jeff, Mullen, Thomas E., Elkon, Rani, Zhou, Yingchun, Simpson, Dennis A., Bushel, Pierre R., Paules, Richard S., Lobenhofer, Edward K., Hurban, Patrick, Kaufmann, William K.

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Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human Fibroblasts von Zhou, Tong, Chou, Jeff, Zhou, Yingchun, Simpson, Dennis A, Cao, Feng, Bushel, Pierre R, Paules, Richard S, Kaufmann, William K

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SWI/SNF complexes are required for full activation of the DNA-damage response von Smith-Roe, Stephanie L, Nakamura, Jun, Holley, Darcy, Chastain, 2nd, Paul D, Rosson, Gary B, Simpson, Dennis A, Ridpath, John R, Kaufman, David G, Kaufmann, William K, Bultman, Scott J

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Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency von Kumar, Rashmi J, Chao, Hui Xiao, Simpson, Dennis A, Feng, Wanjuan, Cho, Min-Guk, Roberts, Victoria R, Sullivan, Aurora R, Shah, Sonam J, Wozny, Anne-Sophie, Fagan-Solis, Katerina, Kumar, Sunil, Luthman, Adam, Ramsden, Dale A, Purvis, Jeremy E, Gupta, Gaorav P

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A Flexible and Qualitatively Stable Model for Cell Cycle Dynamics Including DNA Damage Effects von Jeffries, Clark D., Johnson, Charles R., Zhou, Tong, Simpson, Dennis A., Kaufmann, William K.

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Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts von Smith-Roe, Stephanie L., Patel, Shivani S., Zhou, Yingchun, Simpson, Dennis A., Rao, Shangbang, Ibrahim, Joseph G., Cordeiro-Stone, Marila, Kaufmann, William K.

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An Attenuating Mutation in nsP1 of the Sindbis-Group Virus S.A.AR86 Accelerates Nonstructural Protein Processing and Up-Regulates Viral 26S RNA Synthesis von Heise, Mark T, White, Laura J, Simpson, Dennis A, Leonard, Christopher, Bernard, Kristen A, Meeker, Rick B, Johnston, Robert E

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A predictive mathematical model of the DNA damage G2 checkpoint von Kesseler, Kevin J., Blinov, Michael L., Elston, Timothy C., Kaufmann, William K., Simpson, Dennis A.

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Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines von Cordeiro-Stone, Marila, McNulty, John J., Sproul, Christopher D., Chastain, Paul D., Gibbs-Flournoy, Eugene, Zhou, Yingchun, Carson, Craig, Rao, Shangbang, Mitchell, David L., Simpson, Dennis A., Thomas, Nancy E., Ibrahim, Joseph G., Kaufmann, William K.

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