Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders von FINANGER HEDDERICK, E. L, SIMMERS, J. L, ANDRES-MATEOS, A. Soleimani E, MARX, R, FILES, D. C, KING, L, CRAWFORD, T. O, CORSE, A. M, COHN, R. D

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G.P.84 Mislocalization of nNOS alters the interactions between nNOS and proteins involved with muscle contraction in steroid-induced myopathy von Simmers, J.L, Chaerkady, R, Hedderick, E. Finanger, Marx, R, Mejias, R, Pandey, A, Cohn, R

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T.O.6 Myostatin inhibitor ActIIb rescues atrophy and protects muscle growth signaling pathways in immobilization but not denervation von MacDonald, E.M, Simmers, J.L, Andres-Mateos, E, Mejias-Estevez, R.M, Lee, S.J, Cohn, R.D

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T.O.8 Age-dependent effects of angiotensin II blockade on disuse atrophy von Burks, T.N, Lucas, O, Andres-Mateos, E, Marx, R, Simmers, J.L, Walston, J.D, Cohn, R.D

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Dabigatran versus Warfarin in Patients with Atrial Fibrillation von Connolly, Stuart J, Ezekowitz, Michael D, Yusuf, Salim, Eikelboom, John, Oldgren, Jonas, Parekh, Amit, Pogue, Janice, Reilly, Paul A, Themeles, Ellison, Varrone, Jeanne, Wang, Susan, Alings, Marco, Xavier, Denis, Zhu, Jun, Diaz, Rafael, Lewis, Basil S, Darius, Harald, Diener, Hans-Christoph, Joyner, Campbell D, Wallentin, Lars

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Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro von Dash, A, Simmers, M B, Deering, T G, Berry, D J, Feaver, R E, Hastings, N E, Pruett, T L, LeCluyse, E L, Blackman, B R, Wamhoff, B R

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Dabigatran With or Without Concomitant Aspirin Compared With Warfarin Alone in Patients With Nonvalvular Atrial Fibrillation (PETRO Study) von Ezekowitz, Michael D., MD, PhD, Reilly, Paul A., PhD, Nehmiz, Gerhard, PhD, Simmers, Timothy A., MD, Nagarakanti, Rangadham, MD, Parcham-Azad, Kambiz, MD, Pedersen, K. Erik, MD, Lionetti, Dominick A., MA, Stangier, Joachim, PhD, Wallentin, Lars, MD, PhD

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Subclinical Atrial Fibrillation and the Risk of Stroke von Healey, Jeff S, Connolly, Stuart J, Gold, Michael R, Israel, Carsten W, Van Gelder, Isabelle C, Capucci, Alessandro, Lau, C.P, Fain, Eric, Yang, Sean, Bailleul, Christophe, Morillo, Carlos A, Carlson, Mark, Themeles, Ellison, Kaufman, Elizabeth S, Hohnloser, Stefan H

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Propriospinal Circuitry Underlying Interlimb Coordination in Mammalian Quadrupedal Locomotion von Juvin, Laurent, Simmers, John, Morin, Didier

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Antibacterial Envelope to Prevent Cardiac Implantable Device Infection von Tarakji, Khaldoun G, Mittal, Suneet, Kennergren, Charles, Corey, Ralph, Poole, Jeanne E, Schloss, Edward, Gallastegui, Jose, Pickett, Robert A, Evonich, Rudolph, Philippon, François, McComb, Janet M, Roark, Steven F, Sorrentino, Denise, Sholevar, Darius, Cronin, Edmond, Berman, Brett, Riggio, David, Biffi, Mauro, Khan, Hafiza, Silver, Marc T, Collier, Jack, Eldadah, Zayd, Wright, David J, Lande, Jeff D, Lexcen, Daniel R, Cheng, Alan, Wilkoff, Bruce L

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Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial von Diener, Hans-Christoph, Prof, Dr, Eikelboom, John, Prof, Connolly, Stuart J, Prof, Joyner, Campbell D, Prof, Hart, Robert G, Prof, Lip, Gregory YH, Prof, O'Donnell, Martin, MD, Hohnloser, Stefan H, Prof, Hankey, Graeme J, Prof, Shestakovska, Olga, MSc, Yusuf, Salim, Prof

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A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-associated Skeletal Muscle Wasting von CLARK FILES, D, D'ALESSIO, Franco R, WILLIS, Monte S, PATTERSON, Cam, TANKERSLEY, Clarke G, MESSI, Maria L, CHUN LIU, DELBONO, Osvaldo, DAVID FURLOW, J, BODINE, Sue C, COHN, Ronald D, KING, Landon S, JOHNSTON, Laura F, CROW, Michael T, KESARI, Priya, AGGARWAL, Neil R, GARIBALDI, Brian T, MOCK, Jason R, SIMMERS, Jessica L, DEGORORDO, Antonio, MURDOCH, Jared

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Early performance of a miniaturized leadless cardiac pacemaker: the Micra Transcatheter Pacing Study von Ritter, Philippe, Duray, Gabor Z, Steinwender, Clemens, Soejima, Kyoko, Omar, Razali, Mont, Lluís, Boersma, Lucas V A, Knops, Reinoud E, Chinitz, Larry, Zhang, Shu, Narasimhan, Calambur, Hummel, John, Lloyd, Michael, Simmers, Timothy Alexander, Voigt, Andrew, Laager, Verla, Stromberg, Kurt, Bonner, Matthew D, Sheldon, Todd J, Reynolds, Dwight

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Causes of Death and Influencing Factors in Patients With Atrial Fibrillation: A Competing-Risk Analysis From the Randomized Evaluation of Long-Term Anticoagulant Therapy Study von Marijon, Eloi, Le Heuzey, Jean-Yves, Connolly, Stuart, Yang, Sean, Pogue, Janice, Brueckmann, Martina, Eikelboom, John, Themeles, Ellison, Ezekowitz, Michael, Wallentin, Lars, Yusuf, Salim

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Clinical performance of implantable cardioverter-defibrillator lead monitoring diagnostics von Poole, Jeanne E., Swerdlow, Charles D., Tarakji, Khaldoun G., Mittal, Suneet, Ellenbogen, Kenneth A., Greenspon, Arnold J., Kennergren, Charles, Philbert, Berit T., Moore, JoEllyn, Jones, R. Chris, Schaller, Robert D., Hansalia, Riple, Simmers, Timothy, Mihalcz, Attila, DeBus, Becky, Lexcen, Daniel R., Gunderson, Bruce, Wilkoff, Bruce L.

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Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes von Chapman, Kimberly A., Collado, Maria S., Figler, Robert A., Hoang, Stephen A., Armstrong, Allison J., Cui, Wanxing, Purdy, Michael, Simmers, Michael B., Yazigi, Nada A., Summar, Marshall L., Wamhoff, Brian R., Dash, Ajit

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To guide future practice, perinatal trials should be much larger, simpler and less fragile with close to 100% ascertainment of mortality and other key outcomes von Tarnow-Mordi, William Odita, Robledo, Kristy, Marschner, Ian, Seidler, Lene, Simes, John, Rieger, I., Osborn, D., Popat, H., Reid, S., de Waal, K., Wright, I., Wright, A., Buchan, J., Stubbs, M., Newnham, J., Simmer, K., Young, C., Loh, D., Kok, Y., Gill, A., Kluckow, M., Morris, J., Jeffery, M., Chen, Y., Morris, S., Sinhal, S., Cornthwaite, K., Walker, S., Watkins, A., Collins, C., Holberton, J., Noble, E., Sehgal, A., Yeomans, E., Elsayed, K., Mohamed, A.L., Broom, M., Koh, G., Lawrence, A., Liley, H., Gardener, G., Fox, J., Cartwright, D., Koorts, P., Pritchard, M., McKeown, L., Lui, K., Lainchbury, A., Shand, A., Michalowski, J., Smyth, J., Bolisetty, S., Adno, A., Lee, G., Seidler, Anna Lene, Askie, Lisa, Groom, K., Eaglen, D., Baker, E., Patel, H., Wilkes, N., Gullam, J., Austin, N., Leishman, D., Weston, P., White, N., Cooper, N., Broadbent, R., Stitely, M., Dawson, P., El-Naggar, W., Furlong, M., de Luca, D., Benachi, A., Letamendia, E., Escourrou, G., Dell'Orto, V., Sweet, D., Millar, M., Eltayeb, M., Sheikh, L., Ariff, S., Soll, R., Morris, E., Young, L., Evans, S., Belfort, M., Aagaard, K., Pammi, M., Mandy, G., Gandhi, M.

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1261Geographical variations in the incidence of CIED infection and infection prevention strategies: Update from the global WRAP-IT study von Kennergren, C, Poole, J E, Wilkoff, B L, Mittal, S, Corey, G R, Mccomb, J, Diemberger, I, Wright, D J, Philbert, B T, Simmers, T A, Boersma, L V A, Debus, B, Krueger, J, Vandersteegen, K, Tarakji, K G

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Vestibular lesion-induced developmental plasticity in spinal locomotor networks during Xenopus laevis metamorphosis von Beyeler, Anna, Rao, Guillaume, Ladepeche, Laurent, Jacques, André, Simmers, John, Le Ray, Didier

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B-PO01-034 CLINICAL PERFORMANCE OF IMPLANTABLE CARDIOVERTER DEFIBRILLATOR LEAD MONITORING FEATURES von Poole, Jeanne E., Swerdlow, Charles D., Tarakji, Khaldoun G., Mittal, Suneet, Ellenbogen, Kenneth A., Greenspon, Arnold J., Kennergren, Charles E.H., Thornvig Philbert, Berit, Moore, JoEllyn C., Jones, Robert C., Schaller, Robert D., Hansalia, Riple J., Simmers, Tim A., Mihalcz, Attila, DeBus, Becky, Lexcen, Dan, Gunderson, Bruce D., Wilkoff, Bruce L.

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