SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect FA translocation von Jay, Anthony G., Simard, Jeffrey R., Huang, Nasi, Hamilton, James A.

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Location of High and Low Affinity Fatty Acid Binding Sites on Human Serum Albumin Revealed by NMR Drug-competition Analysis von Simard, Jeffrey R., Zunszain, Patricia A., Hamilton, James A., Curry, Stephen

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Development of a Fluorescent-Tagged Kinase Assay System for the Detection and Characterization of Allosteric Kinase Inhibitors von Simard, Jeffrey R, Getlik, Matthäus, Grütter, Christian, Pawar, Vijaykumar, Wulfert, Sabine, Rabiller, Matthias, Rauh, Daniel

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Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators von Huang, Xin, Shaffer, Paul L, Ayube, Shawn, Bregman, Howard, Chen, Hao, Lehto, Sonya G, Luther, Jason A, Matson, David J, McDonough, Stefan I, Michelsen, Klaus, Plant, Matthew H, Schneider, Stephen, Simard, Jeffrey R, Teffera, Yohannes, Yi, Shuyan, Zhang, Maosheng, DiMauro, Erin F, Gingras, Jacinthe

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A new screening assay for allosteric inhibitors of cSrc von Getlik, Matthäus, Rabiller, Matthias, Rauh, Daniel, Grütter, Christian, Klüter, Sabine, Simard, Jeffrey R, Rode, Haridas B

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Selective Detection of Allosteric Phosphatase Inhibitors von Schneider, Ralf, Beumer, Claudia, Simard, Jeffrey R, Grütter, Christian, Rauh, Daniel

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Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase von Getlik, Matthäus, Simard, Jeffrey R, Termathe, Martin, Grütter, Christian, Rabiller, Matthias, van Otterlo, Willem A L, Rauh, Daniel

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Proteus in the World of Proteins: Conformational Changes in Protein Kinases von Rabiller, Matthias, Getlik, Matthäus, Klüter, Sabine, Richters, André, Tückmantel, Sandra, Simard, Jeffrey R., Rauh, Daniel

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Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance von Klüter, Sabine, Simard, Jeffrey R, Rode, Haridas B, Grütter, Christian, Pawar, Vijaykumar, Raaijmakers, Hans C.A, Barf, Tjeerd A, Rabiller, Matthias, van Otterlo, Willem A.L, Rauh, Daniel

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Direct monitoring of the conformational equilibria of the activation loop in the mitogen-activated protein kinase p38α von Roser, Patrick, Weisner, Jörn, Simard, Jeffrey R, Rauh, Daniel, Drescher, Malte

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Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity von Simard, Jeffrey R, Meshulam, Tova, Pillai, Biju K, Kirber, Michael T, Brunaldi, Kellen, Xu, Su, Pilch, Paul F, Hamilton, James A

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Development and implementation of a high-throughput AlphaLISA assay for identifying inhibitors of EZH2 methyltransferase von Simard, Jeffrey R, Plant, Matthew, Emkey, Renee, Yu, Violeta

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Modulation of Ligand-Gated Glycine Receptors Via Functional Monoclonal Antibodies von Simard, Jeffrey R., Michelsen, Klaus, Wang, Yan, Yang, Chunhua, Youngblood, Beth, Grubinska, Barbara, Taborn, Kristin, Gillie, Daniel J., Cook, Kevin, Chung, Kyu, Long, Alexander M., Hall, Brian E., Shaffer, Paul L., Foti, Robert S., Gingras, Jacinthe

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Chemogenomic Profiling Provides Insights into the Limited Activity of Irreversible EGFR Inhibitors in Tumor Cells Expressing the T790M EGFR Resistance Mutation von SOS, Martin L, RODE, Haridas B, RUDDIGKEIT, Lars, RABILLER, Matthias, KOKER, Mirjam, SIMARD, Jeffrey R, GETLIK, Matthäus, YUZA, Yuki, CHEN, Tzu-Hsiu, GREULICH, Heidi, THOMAS, Roman K, RAUH, Daniel, HEYNCK, Stefanie, PEIFER, Martin, FISCHER, Florian, KLÜTE, Sabine, PAWAR, Vijaykumar G, REUTER, Cecile, HEUCKMANN, Johannes M, WEISS, Jonathan

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FLiK: a direct-binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations von Simard, Jeffrey R, Rauh, Daniel

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Hybrid Compound Design To Overcome the Gatekeeper T338M Mutation in cSrc von Getlik, Matthäus, Grütter, Christian, Simard, Jeffrey R, Klüter, Sabine, Rabiller, Matthias, Rode, Haridas B, Robubi, Armin, Rauh, Daniel

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Chemical and Structural Biology to Direct the Repurposing of Sulindac von Simard, Jeffrey R., Rauh, Daniel

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Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target von Tückmantel, Sandra, Greul, Jörg N, Janning, Petra, Brockmeyer, Andreas, Grütter, Christian, Simard, Jeffrey R, Gutbrod, Oliver, Beck, Michael E, Tietjen, Klaus, Rauh, Daniel, Schreier, Peter H

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The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors von Bregman, Howard, Simard, Jeffrey R, Andrews, Kristin L, Ayube, Shawn, Chen, Hao, Gunaydin, Hakan, Guzman-Perez, Angel, Hu, Jiali, Huang, Liyue, Huang, Xin, Krolikowski, Paul H, Lehto, Sonya G, Lewis, Richard T, Michelsen, Klaus, Pegman, Pamela, Plant, Matthew H, Shaffer, Paul L, Teffera, Yohannes, Yi, Shuyan, Zhang, Maosheng, Gingras, Jacinthe, DiMauro, Erin F

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Identification of Type II and III DDR2 Inhibitors von Richters, André, Nguyen, Hoang D, Phan, Trang, Simard, Jeffrey R, Grütter, Christian, Engel, Julian, Rauh, Daniel

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