CDK7 inhibitors as anticancer drugs von Sava, Georgina P., Fan, Hailing, Coombes, R. Charles, Buluwela, Lakjaya, Ali, Simak

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Light-triggered enzymatic reactions in nested vesicle reactors von Hindley, James W., Elani, Yuval, McGilvery, Catriona M., Ali, Simak, Bevan, Charlotte L., Law, Robert V., Ces, Oscar

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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance von Martin, Lesley-Ann, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Pancholi, Sunil, Tenev, Tencho, Gellert, Pascal, Buluwela, Laki, Harrod, Alison, Thornhill, Allan, Nikitorowicz-Buniak, Joanna, Bhamra, Amandeep, Turgeon, Marc-Olivier, Poulogiannis, George, Gao, Qiong, Martins, Vera, Hills, Margaret, Garcia-Murillas, Isaac, Fribbens, Charlotte, Patani, Neill, Li, Zheqi, Sikora, Matthew J., Turner, Nicholas, Zwart, Wilbert, Oesterreich, Steffi, Carroll, Jason, Ali, Simak, Dowsett, Mitch

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Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts von Shaw, Jacqueline A, Guttery, David S, Hills, Allison, Fernandez-Garcia, Daniel, Page, Karen, Rosales, Brenda M, Goddard, Kate S, Hastings, Robert K, Luo, Jinli, Ogle, Olivia, Woodley, Laura, Ali, Simak, Stebbing, Justin, Coombes, R Charles

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ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation von Li, Zheqi, McGinn, Olivia, Wu, Yang, Bahreini, Amir, Priedigkeit, Nolan M., Ding, Kai, Onkar, Sayali, Lampenfeld, Caleb, Sartorius, Carol A., Miller, Lori, Rosenzweig, Margaret, Cohen, Ofir, Wagle, Nikhil, Richer, Jennifer K., Muller, William J., Buluwela, Laki, Ali, Simak, Bruno, Tullia C., Vignali, Dario A. A., Fang, Yusi, Zhu, Li, Tseng, George C., Gertz, Jason, Atkinson, Jennifer M., Lee, Adrian V., Oesterreich, Steffi

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The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation von Smith, Linda, Farzan, Raed, Ali, Simak, Buluwela, Laki, Saurin, Adrian T., Meek, David W.

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Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer von Giannoudis, Athina, Malki, Mohammed Imad, Rudraraju, Bharath, Mohhamed, Hisham, Menon, Suraj, Liloglou, Triantafillos, Ali, Simak, Carroll, Jason S., Palmieri, Carlo

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Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence von Aouad, Patrick, Zhang, Yueyun, De Martino, Fabio, Stibolt, Céline, Ali, Simak, Ambrosini, Giovanna, Mani, Sendurai A., Maggs, Kelly, Quinn, Hazel M., Sflomos, George, Brisken, Cathrin

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Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer von Baker, Simon C., Mason, Andrew S., Slip, Raphael G., Skinner, Katie T., Macdonald, Andrew, Masood, Omar, Harris, Reuben S., Fenton, Tim R., Periyasamy, Manikandan, Ali, Simak, Southgate, Jennifer

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Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice von Cheng, Julia N, Frye, Jennifer B, Whitman, Susan A, Ehsani, Sima, Ali, Simak, Funk, Janet L

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ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment von Patel, Hetal, Periyasamy, Manikandan, Sava, Georgina P, Bondke, Alexander, Slafer, Brian W, Kroll, Sebastian H B, Barbazanges, Marion, Starkey, Richard, Ottaviani, Silvia, Harrod, Alison, Aboagye, Eric O, Buluwela, Laki, Fuchter, Matthew J, Barrett, Anthony G M, Coombes, R Charles, Ali, Simak

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Noninvasive detection of activating estrogen receptor 1 (ESR1) mutations in estrogen receptor-positive metastatic breast cancer von Guttery, David S, Page, Karen, Hills, Allison, Woodley, Laura, Marchese, Stephanie D, Rghebi, Basma, Hastings, Robert K, Luo, Jinli, Pringle, J Howard, Stebbing, Justin, Coombes, R Charles, Ali, Simak, Shaw, Jacqueline A

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Endocrine-responsive breast cancer and strategies for combating resistance von Ali, Simak, Coombes, R. Charles

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Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform von Alexandrou, George, Moser, Nicolas, Mantikas, Katerina-Theresa, Rodriguez-Manzano, Jesus, Ali, Simak, Coombes, R Charles, Shaw, Jacqui, Georgiou, Pantelis, Toumazou, Christopher, Kalofonou, Melpomeni

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Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis von Aleskandarany, Mohammad A., Abduljabbar, Rezvan, Ashankyty, Ibraheem, Elmouna, Ahmed, Jerjees, Dena, Ali, Simak, Buluwela, Laki, Diez-Rodriguez, Maria, Caldas, Carlos, Green, Andrew R., Ellis, Ian O., Rakha, Emad A.

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p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells von Periyasamy, Manikandan, Singh, Anup K, Gemma, Carolina, Kranjec, Christian, Farzan, Raed, Leach, Damien A, Navaratnam, Naveenan, Pálinkás, Hajnalka L, Vértessy, Beata G, Fenton, Tim R, Doorbar, John, Fuller-Pace, Frances, Meek, David W, Coombes, R Charles, Buluwela, Laki, Ali, Simak

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Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion von Nguyen, Van T. M., Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H., Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Meira, Alba, Patten, Darren K., Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R. Charles, Magnani, Luca

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Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB von Periyasamy, Manikandan, Singh, Anup K., Gemma, Carolina, Farzan, Raed, Allsopp, Rebecca C., Shaw, Jacqueline A., Charmsaz, Sara, Young, Leonie S., Cunnea, Paula, Coombes, R. Charles, Győrffy, Balázs, Buluwela, Lakjaya, Ali, Simak

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A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation von Kalofonou, Melpomeni, Malpartida-Cardenas, Kenny, Alexandrou, George, Rodriguez-Manzano, Jesus, Yu, Ling-Shan, Miscourides, Nicholas, Allsopp, Rebecca, Gleason, Kelly L. T., Goddard, Katie, Fernandez-Garcia, Daniel, Page, Karen, Georgiou, Pantelis, Ali, Simak, Coombes, R. Charles, Shaw, Jacqueline, Toumazou, Christofer

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A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk von JIRONG LONG, DELAHANTY, Ryan J, ALI, Simak, SHU, Xiao-Ou, WEI ZHENG, GUOLIANG LI, GAO, Yu-Tang, WEI LU, QIUYIN CAI, XIANG, Yong-Bing, CHUN LI, JI, Bu-Tian, YING ZHENG

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