An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 von Thoreen, Carson C., Kang, Seong A., Chang, Jae Won, Liu, Qingsong, Zhang, Jianming, Gao, Yi, Reichling, Laurie J., Sim, Taebo, Sabatini, David M., Gray, Nathanael S.

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Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype von Olson, Calla M., Liang, Yanke, Leggett, Alan, Park, Woojun D., Li, Lianbo, Mills, Caitlin E., Elsarrag, Selma Z., Ficarro, Scott B., Zhang, Tinghu, Düster, Robert, Geyer, Matthias, Sim, Taebo, Marto, Jarrod A., Sorger, Peter K., Westover, Ken D., Lin, Charles Y., Kwiatkowski, Nicholas, Gray, Nathanael S.

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Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors von Tan, Li, Wang, Jun, Tanizaki, Junko, Huang, Zhifeng, Aref, Amir R, Rusan, Maria, Zhu, Su-Jie, Zhang, Yiyun, Ercan, Dalia, Liao, Rachel G, Capelletti, Marzia, Zhou, Wenjun, Hur, Wooyoung, Kim, NamDoo, Sim, Taebo, Gaudet, Suzanne, Barbie, David A, Yeh, Jing-Ruey Joanna, Yun, Cai-Hong, Hammerman, Peter S, Mohammadi, Moosa, Jänne, Pasi A, Gray, Nathanael S

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Antitumor Effects and Mechanisms of AZD4547 on FGFR2-Deregulated Endometrial Cancer Cells von Kwak, Yeonui, Cho, Hanna, Hur, Wooyoung, Sim, Taebo

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Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung Cancer von Chong, Curtis R, Bahcall, Magda, Capelletti, Marzia, Kosaka, Takayuki, Ercan, Dalia, Sim, Taebo, Sholl, Lynette M, Nishino, Mizuki, Johnson, Bruce E, Gray, Nathanael S, Jänne, Pasi A

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Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor von Lim, Sang Min, Westover, Kenneth D., Ficarro, Scott B., Harrison, Rane A., Choi, Hwan Geun, Pacold, Michael E., Carrasco, Martin, Hunter, John, Kim, Nam Doo, Xie, Ting, Sim, Taebo, Jänne, Pasi A., Meyerson, Matthew, Marto, Jarrod A., Engen, John R., Gray, Nathanael S.

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Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs von Cho, Hanna, Kim, Namkyoung, Murakami, Takashi, Sim, Taebo

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Acquired METD1228V Mutation and Resistance to MET Inhibition in Lung Cancer von Bahcall, Magda, Sim, Taebo, Paweletz, Cloud P, Patel, Jyoti D, Alden, Ryan S, Kuang, Yanan, Sacher, Adrian G, Kim, Nam Doo, Lydon, Christine A, Awad, Mark M, Jaklitsch, Michael T, Sholl, Lynette M, Jänne, Pasi A, Oxnard, Geoffrey R

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Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapa... von Liu, Qingsong, Chang, Jae Won, Wang, Jinhua, Kang, Seong A, Thoreen, Carson C, Markhard, Andrew, Hur, Wooyoung, Zhang, Jianming, Sim, Taebo, Sabatini, David M, Gray, Nathanael S

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Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion von Song, Chiman, Bae, Yeonju, Jun, JinJoo, Lee, Hyomin, Kim, Nam Doo, Lee, Kyung-Bok, Hur, Wooyoung, Park, Jae-Yong, Sim, Taebo

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AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis von Kim, Hyunjoo, Jeong, Muhah, Na, Do-Hyeong, Ryu, Shin-Hyeon, Jeong, Eun Il, Jung, Kwangmin, Kang, Jaemin, Lee, Ho-June, Sim, Taebo, Yu, Dae-Yeul, Yu, Hee Chul, Cho, Baik-Hwan, Jung, Yong-Keun

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Anti-cancer effects of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one derivatives on hepatocellular carcinoma harboring FGFR4 activation von Nam, Yunju, Shin, Injae, Kim, Younghoon, Ryu, SeongShick, Kim, Namdoo, Ju, Eunhye, Sim, Taebo

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A Concise and Efficient Total Synthesis of Militarinone D von Dash, Uttam, Sengupta, Sandip, Sim, Taebo

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A novel NLRP3 inhibitor as a therapeutic agent against monosodium urate-induced gout von Park, Kihyoun, Shin, Injae, Kim, Yoonseon, Kang, Hyereen, Oh, Soo-Jin, Jang, Eunkyeong, Sim, Taebo, Youn, Jeehee, Lee, Myung-Shik

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Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo von Sundberg, Thomas B, Liang, Yanke, Wu, Huixian, Choi, Hwan Geun, Kim, Nam Doo, Sim, Taebo, Johannessen, Liv, Petrone, Adam, Khor, Bernard, Graham, Daniel B, Latorre, Isabel J, Phillips, Andrew J, Schreiber, Stuart L, Perez, Jose, Shamji, Alykhan F, Gray, Nathanael S, Xavier, Ramnik J

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Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors von Nam, Yunju, Hwang, Dongkeun, Kim, Namdoo, Seo, Hong-Seog, Selim, Khalid B., Sim, Taebo

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Allosteric inhibitors of Bcr-abl-dependent cell proliferation von Gray, Nathanael S, Adrián, Francisco J, Ding, Qiang, Sim, Taebo, Velentza, Anastasia, Sloan, Christine, Liu, Yi, Zhang, Guobao, Hur, Wooyoung, Ding, Sheng, Manley, Paul, Mestan, Jürgen, Fabbro, Doriano

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Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor von Yoon, Hojong, Shin, Injae, Nam, Yunju, Kim, Nam Doo, Lee, Kyung-Bok, Sim, Taebo

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Affinity‐Directed Site‐Specific Protein Labeling and Its Application to Antibody‐Drug Conjugates von Kim, Sooin, Kim, Sanggil, Kim, Sangji, Kim, Namkyoung, Lee, Sang Won, Yi, Hanbin, Lee, Seungeun, Sim, Taebo, Kwon, Yongseok, Lee, Hyun Soo

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Novel Small Molecules Capable of Blocking mtRAS-Signaling Pathway von Kim, Namkyoung, Shin, Injae, Kim, Younghoon, Jeon, Eunhye, Lee, Jiwon, Lee, Chaeyoung, Nam, Yunju, Lee, Sumin, Ju, Eunhye, Kim, Chan, Son, Woolim, Ryu, SeongShick, Ko, Minjoo, Sim, Taebo

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