Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis von Bachelez, Hervé, Choon, Siew-Eng, Marrakchi, Slaheddine, Burden, A. David, Tsai, Tsen-Fang, Morita, Akimichi, Turki, Hamida, Hall, David B, Shear, Michael, Baum, Patrick, Padula, Steven J, Thoma, Christian

Volltext

Trial of Spesolimab for Generalized Pustular Psoriasis von Bachelez, Hervé, Choon, Siew-Eng, Marrakchi, Slaheddine, Burden, A. David, Tsai, Tsen-Fang, Morita, Akimichi, Navarini, Alexander A, Zheng, Min, Xu, Jinhua, Turki, Hamida, Anadkat, Milan J, Rajeswari, Sushmita, Hua, Hairui, Vulcu, Sebastian D, Hall, David, Tetzlaff, Kay, Thoma, Christian, Lebwohl, Mark G

Volltext

Clinical and genetic differences between pustular psoriasis subtypes von Twelves, Sophie, Mostafa, Alshimaa, Dand, Nick, Burri, Elias, Farkas, Katalin, Wilson, Rosemary, Cooper, Hywel L., Irvine, Alan D., Oon, Hazel H., Kingo, Külli, Köks, Sulev, Mrowietz, Ulrich, Puig, Luis, Reynolds, Nick, Tan, Eugene Sern-Ting, Tanew, Adrian, Torz, Kaspar, Trattner, Hannes, Valentine, Mark, Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Bata-Csörgő, Zsuzsa, Szell, Marta, Griffiths, Christopher E.M., Burden, A. David, Choon, Siew-Eng, Smith, Catherine H., Barker, Jonathan N., Navarini, Alexander A., Capon, Francesca

Volltext

Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians von Wang, Chuang-Wei, Tassaneeyakul, Wichittra, Chen, Chun-Bing, Chen, Wei-Ti, Teng, Yu-Chuan, Huang, Cheng-Yang, Sukasem, Chonlaphat, Lu, Chun-Wei, Lee, Yun-Shien, Choon, Siew-Eng, Nakkam, Nontaya, Hui, Rosaline Chung-Yee, Huang, Yen-Hua, Chang, Ya-Ching, Lin, Yang Yu-Wei, Chang, Chee-Jen, Chiu, Tsu-Man, Chantratita, Wasun, Konyoung, Parinya, Lee, Chaw-Ning, Klaewsongkram, Jettanong, Rerkpattanapipat, Ticha, Amornpinyo, Warayuwadee, Saksit, Niwat, Rerknimitr, Pawinee, Huang, Yu Huei, Lin, Shang-Hung, Hsu, Chao-Kai, Chan, Cheng-Chi, Lin, Yu-Jr, Hung, Shuen-Iu, Chung, Wen-Hung

Volltext

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production von Mahil, Satveer K., Twelves, Sophie, Farkas, Katalin, Setta-Kaffetzi, Niovi, Burden, A. David, Gach, Joanna E., Irvine, Alan D., Képíró, László, Mockenhaupt, Maja, Oon, Hazel H., Pinner, Jason, Ranki, Annamari, Seyger, Marieke M.B., Soler-Palacin, Pere, Storan, Eoin R., Tan, Eugene S., Valeyrie-Allanore, Laurence, Young, Helen S., Trembath, Richard C., Choon, Siew-Eng, Szell, Marta, Bata-Csorgo, Zsuzsanna, Smith, Catherine H., Di Meglio, Paola, Barker, Jonathan N., Capon, Francesca

Volltext

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis von Catapano, Marika, Vergnano, Marta, Romano, Marco, Mahil, Satveer K., Choon, Siew-Eng, Burden, A. David, Young, Helen S., Carr, Ian M., Lachmann, Helen J., Lombardi, Giovanna, Smith, Catherine H., Ciccarelli, Francesca D., Barker, Jonathan N., Capon, Francesca

Volltext

Efficacy and safety of spesolimab in Asian patients with a generalized pustular psoriasis flare: Results from the randomized, double‐blind, placebo‐controlled Effisayil™ 1 study... von Morita, Akimichi, Tsai, Tsen‐Fang, Yee, Evelyn Yap Wen, Okubo, Yukari, Imafuku, Shinichi, Zheng, Min, Li, Ling, Quaresma, Manuel, Thoma, Christian, Choon, Siew Eng

Volltext

Time to accurately determine the burden of generalized pustular psoriasis at the population level von Choon, Siew Eng, Bachelez, Hervé

Volltext

Understanding generalized pustular psoriasis for improved patient care von Choon, Siew Eng, Barker, Jonathan, Bachelez, Herve

Volltext

Rare Pathogenic Variants in IL36RN Underlie a Spectrum of Psoriasis-Associated Pustular Phenotypes von Setta-Kaffetzi, Niovi, Navarini, Alexander A., Patel, Varsha M., Pullabhatla, Venu, Pink, Andrew E., Choon, Siew-Eng, Allen, Michael A., Burden, A David, Griffiths, Christopher E.M., Seyger, Marieke M.B., Kirby, Brian, Trembath, Richard C., Simpson, Michael A., Smith, Catherine H., Capon, Francesca, Barker, Jonathan N.

Volltext

Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease von Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Abraham, Thamir, Ali, Mahmud, August, Suzannah, Baudry, David, Bewley, Anthony, Cooper, Hywel, Griffiths, Christopher E.M., Ingram, John, Kelly, Susan, Korshid, Mohsen, Ladoyanni, Effie, McKenna, John, Meynell, Freya, Parslew, Richard, Patel, Prakash, Pushparajah, Angela, Reynolds, Nick, Smith, Catherine, Wahie, Shyamal, Warren, Richard, Wright, Andrew, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca

Volltext

Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions von Chung, Wen-Hung, Chang, Wan-Chun, Lee, Yun-Shien, Wu, Ying-Ying, Yang, Chih-Hsun, Ho, Hsin-Chun, Chen, Ming-Jing, Lin, Jing-Yi, Hui, Rosaline Chung-Yee, Ho, Ji-Chen, Wu, Wei-Ming, Chen, Ting-Jui, Wu, Tony, Wu, Yih-Ru, Hsih, Mo-Song, Tu, Po-Hsun, Chang, Chen-Nen, Hsu, Chien-Ning, Wu, Tsu-Lan, Choon, Siew-Eng, Hsu, Chao-Kai, Chen, Der-Yuan, Liu, Chin-San, Lin, Ching-Yuang, Kaniwa, Nahoko, Saito, Yoshiro, Takahashi, Yukitoshi, Nakamura, Ryosuke, Azukizawa, Hiroaki, Shi, Yongyong, Wang, Tzu-Hao, Chuang, Shiow-Shuh, Tsai, Shih-Feng, Chang, Chee-Jen, Chang, Yu-Sun, Hung, Shuen-Iu

Volltext

The Function of HLA-B13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions von Chen, Wei-Ti, Wang, Chuang-Wei, Lu, Chun-Wei, Chen, Chun-Bing, Lee, Hua-En, Hung, Shuen-Iu, Choon, Siew-Eng, Yang, Chih-Hsun, Liu, Ming-Tsan, Chen, Ting Jui, Fan, Wen-Lang, Su, Shih-Chi, Lin, Yang Yu-Wei, Chang, Ya-Ching, Chung, Wen-Hung

Volltext

Juvenile generalized pustular psoriasis is a chronic recalcitrant disease: an analysis of 27 patients seen in a tertiary hospital in Johor, Malaysia von Lau, Bi‐Wen, Lim, Dee‐Zhen, Capon, Francesca, Barker, Jonathan N., Choon, Siew‐Eng

Volltext

AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking von Setta-Kaffetzi, Niovi, Simpson, Michael A., Navarini, Alexander A., Patel, Varsha M., Lu, Hui-Chun, Allen, Michael H., Duckworth, Michael, Bachelez, Hervé, Burden, A. David, Choon, Siew-Eng, Griffiths, Christopher E.M., Kirby, Brian, Kolios, Antonios, Seyger, Marieke M.B., Prins, Christa, Smahi, Asma, Trembath, Richard C., Fraternali, Franca, Smith, Catherine H., Barker, Jonathan N., Capon, Francesca

Volltext

Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris von Berki, Dorottya M., Liu, Lu, Choon, Siew-Eng, David Burden, A., Griffiths, Christopher E.M., Navarini, Alexander A., Tan, Eugene S., Irvine, Alan D., Ranki, Annamari, Ogo, Takeshi, Petrof, Gabriela, Mahil, Satveer K., Duckworth, Michael, Allen, Michael H., Vito, Pasquale, Trembath, Richard C., McGrath, John, Smith, Catherine H., Capon, Francesca, Barker, Jonathan N.

Volltext

Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised, placebo-control... von Morita, Akimichi, Strober, Bruce, Burden, A David, Choon, Siew Eng, Anadkat, Milan J, Marrakchi, Slaheddine, Tsai, Tsen-Fang, Gordon, Kenneth B, Thaçi, Diamant, Zheng, Min, Hu, Na, Haeufel, Thomas, Thoma, Christian, Lebwohl, Mark G

Volltext

DNA methylation of ITGB2 contributes to allopurinol hypersensitivity von Liu, Yu, Wang, Chuang-Wei, Chen, Chun-Bing, Yu, Kuang-Hui, Wu, Yeong-Jian, Choon, Siew-Eng, Chang, Wan-Chun, Yang, Fanping, Luo, Xiao-Qun, Chung, Wen-Hung, Zhao, Ming, Lu, Qian-Jin

Volltext

IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis von Hussain, Safia, BSc, Berki, Dorottya M., BSc, Choon, Siew-Eng, MRCP, Burden, A. David, MD, FRCP, Allen, Michael H., PhD, Arostegui, Juan I., MD, PhD, Chaves, Antonio, MD, Duckworth, Michael, Irvine, Alan D., MD, Mockenhaupt, Maja, MD, PhD, Navarini, Alexander A., MD, PhD, Seyger, Marieke M.B., MD, PhD, Soler-Palacin, Pere, MD, PhD, Prins, Christa, MD, Valeyrie-Allanore, Laurence, MD, Vicente, M. Asuncion, MD, Trembath, Richard C., FMedSci, Smith, Catherine H., MD, FRCP, Barker, Jonathan N., MD, FRCP, Capon, Francesca, PhD

Volltext

Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi‐ethnic Johor Bahru, Malaysia von Choon, Siew Eng, Tok, Peter Seah Keng, Wong, Kit Wan, Lim, Yee Ting, Nanu, Nalini M., Barker, Jonathan N., Capon, Francesca

Volltext