Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors von Siemers, Nathan O, Holloway, James L, Chang, Han, Chasalow, Scott D, Ross-MacDonald, Petra B, Voliva, Charles F, Szustakowski, Joseph D

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Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines von Chang, Han, Jackson, Donald G, Kayne, Paul S, Ross-Macdonald, Petra B, Ryseck, Rolf-Peter, Siemers, Nathan O

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Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment von Szabo, Peter M., Vajdi, Amir, Kumar, Namit, Tolstorukov, Michael Y., Chen, Benjamin J., Edwards, Robin, Ligon, Keith L., Chasalow, Scott D., Chow, Kin-Hoe, Shetty, Aniket, Bolisetty, Mohan, Holloway, James L., Golhar, Ryan, Kidd, Brian A., Hull, Philip Ansumana, Houser, Jeff, Vlach, Logan, Siemers, Nathan O., Saha, Saurabh

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An immune-active tumor microenvironment favors clinical response to ipilimumab von Ji, Rui-Ru, Chasalow, Scott D., Wang, Lisu, Hamid, Omid, Schmidt, Henrik, Cogswell, John, Alaparthy, Suresh, Berman, David, Jure-Kunkel, Maria, Siemers, Nathan O., Jackson, Jeffrey R., Shahabi, Vafa

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Nearest Neighbor Networks: clustering expression data based on gene neighborhoods von Huttenhower, Curtis, Flamholz, Avi I, Landis, Jessica N, Sahi, Sauhard, Myers, Chad L, Olszewski, Kellen L, Hibbs, Matthew A, Siemers, Nathan O, Troyanskaya, Olga G, Coller, Hilary A

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Fc-optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models von Campbell, Joseph R, McDonald, Bryan R, Mesko, Paul B, Siemers, Nathan O, Singh, Priti B, Selby, Mark, Sproul, Tim W, Korman, Alan J, Vlach, Logan M, Houser, Jeff, Sambanthamoorthy, Sharmila, Lu, Kai, Hatcher, Sandra V, Lohre, Jack, Jain, Renu, Lan, Ruth Y

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Analyses of PD-L1 and Inflammatory Gene Expression Association with Efficacy of Nivolumab ± Ipilimumab in Gastric Cancer/Gastroesophageal Junction Cancer von Lei, Ming, Siemers, Nathan O, Pandya, Dimple, Chang, Han, Sanchez, Teresa, Harbison, Christopher, Szabo, Peter M, Janjigian, Yelena, Ott, Patrick A, Sharma, Padmanee, Bendell, Johanna, Evans, Thomas R Jeffry, de Braud, Filippo, Chau, Ian, Boyd, Zachary

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Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities von Ji, Rui-Ru, de Silva, Heshani, Jin, Yisheng, Bruccoleri, Robert E, Cao, Jian, He, Aiqing, Huang, Wenjun, Kayne, Paul S, Neuhaus, Isaac M, Ott, Karl-Heinz, Penhallow, Becky, Cockett, Mark I, Neubauer, Michael G, Siemers, Nathan O, Ross-Macdonald, Petra

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Gene Set Enrichment Analysis von Tilford, Charles A., Siemers, Nathan O.

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HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy von Friedrichs, Frauke, Zugck, Christian, Rauch, Gerd-Jörg, Ivandic, Boris, Weichenhan, Dieter, Müller-Bardorff, Margit, Meder, Benjamin, El Mokhtari, Nour Eddine, Regitz-Zagrosek, Vera, Hetzer, Roland, Schäfer, Arne, Schreiber, Stefan, Chen, Jian, Neuhaus, Isaac, Ji, Ruiru, Siemers, Nathan O, Frey, Norbert, Rottbauer, Wolfgang, Katus, Hugo A, Stoll, Monika

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SDRS—an algorithm for analyzing large-scale dose–response data von Ji, Rui-Ru, Siemers, Nathan O, Lei, Ming, Schweizer, Liang, Bruccoleri, Robert E

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Abstract 2244: Evaluation of large antibody panels in single-cell genomic immunophenotyping of fresh and preserved human leukocytes von Siemers, Nathan O., Chen, Jasmine, Mankoo, Parminder, Ilyas, Shazia

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Development and Activities of a New Melphalan Prodrug Designed for Tumor-Selective Activation von Kerr, David E, Li, Zhengong, Siemers, Nathan O, Senter, Peter D, Vrudhula, Vivekananda M

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Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-β-Lactamase fusion protein von Vrudhula, Vivekananda M., Kerr, David E., Siemers, Nathan O., Dubowchik, Gene M., Senter, Peter D.

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Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase von Constantine, Keith L., Krystek, Stanley R., Healy, Matthew D., Doyle, Michael L., Siemers, Nathan O., Thanassi, Jane, Yan, Ning, Xie, Dianlin, Goldfarb, Valentina, Yanchunas, Joseph, Tao, Li, Dougherty, Brian A., Farmer, Bennett T.

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Comparison of Recombinant and Synthetically Formed Monoclonal Antibody-β-Lactamase Conjugates for Anticancer Prodrug Activation von Kerr, David E, Vrudhula, Vivekananda M, Svensson, Håkan P, Siemers, Nathan O, Senter, Peter D

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Periplanone total synthesis via intramolecular pinacol coupling von McMurry, John E., Siemers, Nathan O.

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Modifying the Specificity and Activity of the Enterobacter cloacae P99 β-Lactamase by Mutagenesis within an M13 Phage Vector von Siemers, Nathan O, Yelton, Dale E, Bajorath, Jürgen, Senter, Peter D

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On the stereochemistry of the titanium-induced intramolecular pinacol coupling reaction von McMurry, John E., Siemers, Nathan O.

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ANTICUERPOS ANTI-CCR8 PARA EL TRATAMIENTO DEL CANCER von MESKO, Paul Blaine, SIEMERS, Nathan O, LEE, John K, DIONG, SJ Jian Zhe, STROP, Pavel, SELBY, Mark J, RAJPAL, Arvind, JHATAKIA, Amy D, BARMAN, Ishita, FINDEISEN, Felix, MCDONALD, Bryan, GREENAWALT, Danielle M, WANG, Xi-Tao, SAMBANTHAMOORTHY, Sharmila, LEE, Peter Sung Keun, JAIN, Renu, LU, Kai, LAN, Ruth Yin-Zong, TERRACINA, Gaby A, ADELAKUN, Olufemi A, LIANG, Linda, CAMPBELL, Joseph Richard

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