O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate von Schoenfeld, Joshua D., Sibenaller, Zita A., Mapuskar, Kranti A., Wagner, Brett A., Cramer-Morales, Kimberly L., Furqan, Muhammad, Sandhu, Sonia, Carlisle, Thomas L., Smith, Mark C., Abu Hejleh, Taher, Berg, Daniel J., Zhang, Jun, Keech, John, Parekh, Kalpaj R., Bhatia, Sudershan, Monga, Varun, Bodeker, Kellie L., Ahmann, Logan, Vollstedt, Sandy, Brown, Heather, Shanahan Kauffman, Erin P., Schall, Mary E., Hohl, Ray J., Clamon, Gerald H., Greenlee, Jeremy D., Howard, Matthew A., Schultz, Michael K., Smith, Brian J., Riley, Dennis P., Domann, Frederick E., Cullen, Joseph J., Buettner, Garry R., Buatti, John M., Spitz, Douglas R., Allen, Bryan G.

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NOTCH3 is a prognostic factor that promotes glioma cell proliferation, migration and invasion via activation of CCND1 and EGFR von Alqudah, Mohammad A Y, Agarwal, Supreet, Al-Keilani, Maha S, Sibenaller, Zita A, Ryken, Timothy C, Assem, Mahfoud

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Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer von Du, Juan, Cieslak, 3rd, John A, Welsh, Jessemae L, Sibenaller, Zita A, Allen, Bryan G, Wagner, Brett A, Kalen, Amanda L, Doskey, Claire M, Strother, Robert K, Button, Anna M, Mott, Sarah L, Smith, Brian, Tsai, Susan, Mezhir, James, Goswami, Prabhat C, Spitz, Douglas R, Buettner, Garry R, Cullen, Joseph J

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Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism von Allen, Bryan G, Bhatia, Sudershan K, Anderson, Carryn M, Eichenberger-Gilmore, Julie M, Sibenaller, Zita A, Mapuskar, Kranti A, Schoenfeld, Joshua D, Buatti, John M, Spitz, Douglas R, Fath, Melissa A

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Manganoporphyrins Increase Ascorbate-Induced Cytotoxicity by Enhancing H2O2 Generation von RAWAL, Malvika, SCHROEDER, Samuel R, WAGNER, Brett A, CUSHING, Cameron M, WELSH, Jessemae L, BUTTON, Anna M, JUAN DU, SIBENALLER, Zita A, BUETTNER, Garry R, CULLEN, Joseph J

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Tumor derived mutations of protein tyrosine phosphatase receptor type k affect its function and alter sensitivity to chemotherapeutics in glioma von Agarwal, Supreet, Al-Keilani, Maha S, Alqudah, Mohammad A Y, Sibenaller, Zita A, Ryken, Timothy C, Assem, Mahfoud

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Trends in brain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to 2001 von Deorah, Sundeep, Lynch, Charles F, Sibenaller, Zita A, Ryken, Timothy C

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Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio-Chemotherapy While Protecting Normal Tissue von Schoenfeld, Joshua D., Alexander, Matthew S., Waldron, Timothy J., Sibenaller, Zita A., Spitz, Douglas R., Buettner, Garry R., Allen, Bryan G., Cullen, Joseph J.

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Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models von Schoenfeld, Joshua D., Sibenaller, Zita A., Mapuskar, Kranti A., Bradley, Megan D., Wagner, Brett A., Buettner, Garry R., Monga, Varun, Milhem, Mohammed, Spitz, Douglas R., Allen, Bryan G.

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Erlotinib-Mediated Inhibition of EGFR Signaling Induces Metabolic Oxidative Stress through NOX4 von ORCUTT, Kevin P, PARSONS, Arlene D, SPITZ, Douglas R, SIMONS, Andrean L, SIBENALLER, Zita A, SCARBROUGH, Peter M, YUEMING ZHU, SOBHAKUMARI, Arya, WILKE, Werner W, KALEN, Amanda L, GOSWAMI, Prabhat, MILLER, Francis J

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Comprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBM von Shah, Nameeta, Lin, Biaoyang, Sibenaller, Zita, Ryken, Timothy, Lee, Hwahyung, Yoon, Jae-Geun, Rostad, Steven, Foltz, Greg

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Pharmacologic ascorbate (P-AscH−) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma von Wilkes, Justin G., O’Leary, Brianne R., Du, Juan, Klinger, Adrienne R., Sibenaller, Zita A., Doskey, Claire M., Gibson-Corley, Katherine N., Alexander, Matthew S., Tsai, Susan, Buettner, Garry R., Cullen, Joseph J.

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Persistent Oxidative Stress in Vestibular Schwannomas After Stereotactic Radiation Therapy von Robinett, Zachary N, Bathla, Girish, Wu, Angela, Clark, James Jason, Sibenaller, Zita A, Wilson, Thomas, Kirby, Patricia, Allen, Bryan G, Hansen, Marlan R

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Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1α in pancreatic cancer von Sibenaller, Zita A, Welsh, Jessemae L, Du, Changbin, Witmer, Jordan R, Schrock, Hannah E, Du, Juan, Buettner, Garry R, Goswami, Prabhat C, Cieslak, 3rd, John A, Cullen, Joseph J

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Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma von SOLOMON, David A, KIM, Jung-Sik, SAMUELS, Yardena, WALDMAN, Todd, CRONIN, Julia C, SIBENALLER, Zita, RYKEN, Timothy, ROSENBERG, Steven A, RESSOM, Habtom, JEAN, Walter, BIGNER, Darell, HAI YAN

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Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma von Foltz, Greg, Ryu, Gi-Yung, Yoon, Jae-Geun, Nelson, Timothy, Fahey, Jessica, Frakes, Amanda, Lee, Hwahyung, Field, Lorie, Zander, Kaitlin, Sibenaller, Zita, Ryken, Timothy C, Vibhakar, Rajeev, Hood, Leroy, Madan, Anup

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Fluorine-18-Labeled Thymidine Positron Emission Tomography (FLT-PET) as an Index of Cell Proliferation after Pharmacological Ascorbate-Based Therapy von Cieslak, John A., Sibenaller, Zita A., Walsh, Susan A., Ponto, Laura L. Boles, Du, Juan, Sunderland, John J., Cullen, Joseph J.

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Genetic characterization of commonly used glioma cell lines in the rat animal model system von Sibenaller, Zita A, Etame, Arnold B, Ali, Mushtaq M, Barua, Manali, Braun, Terry A, Casavant, Thomas L, Ryken, Timothy C

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Sample Type Bias in the Analysis of Cancer Genomes von SOLOMON, David A, KIM, Jung-Sik, RESSOM, Habtom W, SIBENALLER, Zita, RYKEN, Timothy, JEAN, Walter, BIGNER, Darell, HAI YAN, WALDMAN, Todd

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Specific down-regulation of annexin II expression in human cells interferes with cell proliferation von Chiang, Y, Rizzino, A, Sibenaller, Z A, Wold, M S, Vishwanatha, J K

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