Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia von Mullighan, Charles G., Phillips, Letha A., Su, Xiaoping, Ma, Jing, Miller, Christopher B., Shurtleff, Sheila A., Downing, James R.

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Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia... von HAFERLACH, Torsten, KOHLMANN, Alexander, GILKES, Amanda, CHIARETTI, Sabina, SHURTLEFF, Sheila A, KIPPS, Thomas J, RASSENTI, Laura Z, YEOH, Allen E, PAPENHAUSEN, Peter R, LIU, Wei-Min, WILLIAMS, P. Mickey, FOA, Robin, WIECZOREK, Lothar, BASSO, Giuseppe, TE KRONNIE, Geertruy, BONO, Marie-Christine, DE VOS, John, HERNINDEZ, Jesus M, HOFMANN, Wolf-Karsten, MILLS, Ken I

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Comparative Analysis of Different Approaches to Measure Treatment Response in Acute Myeloid Leukemia von Inaba, Hiroto, Coustan-Smith, Elaine, Cao, Xueyuan, Pounds, Stanley B, Shurtleff, Sheila A, Wang, Kathleen Y, Raimondi, Susana C, Onciu, Mihaela, Jacobsen, Jeffrey, Ribeiro, Raul C, Dahl, Gary V, Bowman, W Paul, Taub, Jeffrey W, Degar, Barbara, Leung, Wing, Downing, James R, Pui, Ching-Hon, Rubnitz, Jeffrey E, Campana, Dario

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Phase I Pharmacokinetic and Pharmacodynamic Study of the Multikinase Inhibitor Sorafenib in Combination With Clofarabine and Cytarabine in Pediatric Relapsed/Refractory Leukemia von INABA, Hiroto, RUBNITZ, Jeffrey E, POUNDS, Stanley B, PUI, Ching-Hon, RIBEIRO, Raul C, CAMPANA, Dario, BAKER, Sharyn D, COUSTAN-SMITH, Elaine, LIE LI, FURMANSKI, Brian D, MASCARA, Gerard P, HEYM, Kenneth M, CHRISTENSEN, Robbin, ONCIU, Mihaela, SHURTLEFF, Sheila A

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Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia von Radtke, Ina, Mullighan, Charles G, Ishii, Masami, Su, Xiaoping, Cheng, Jinjun, Ma, Jing, Ganti, Ramapriya, Cai, Zhongling, Goorha, Salil, Pounds, Stanley B, Cao, Xueyuan, Obert, Caroline, Armstrong, Jianling, Zhang, Jinghui, Song, Guangchun, Ribeiro, Raul C, Rubnitz, Jeffrey E, Raimondi, Susana C, Shurtleff, Sheila A, Downing, James R

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Classification of pediatric acute lymphoblastic leukemia by gene expression profiling von Ross, Mary E., Zhou, Xiaodong, Song, Guangchun, Shurtleff, Sheila A., Girtman, Kevin, Williams, W. Kent, Liu, Hsi-Che, Mahfouz, Rami, Raimondi, Susana C., Lenny, Noel, Patel, Anami, Downing, James R.

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Impact of tyrosine kinase inhibitors on minimal residual disease and outcome in childhood Philadelphia chromosome‐positive acute lymphoblastic leukemia von Jeha, Sima, Coustan‐Smith, Elaine, Pei, Deqing, Sandlund, John T., Rubnitz, Jeffrey E., Howard, Scott C., Inaba, Hiroto, Bhojwani, Deepa, Metzger, Monika L., Cheng, Cheng, Choi, John K., Jacobsen, Jeffrey, Shurtleff, Sheila A., Raimondi, Susana, Ribeiro, Raul C., Pui, Ching‐Hon, Campana, Dario

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Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling von Yeoh, Eng-Juh, Ross, Mary E, Shurtleff, Sheila A, Williams, W.Kent, Patel, Divyen, Mahfouz, Rami, Behm, Fred G, Raimondi, Susana C, Relling, Mary V, Patel, Anami, Cheng, Cheng, Campana, Dario, Wilkins, Dawn, Zhou, Xiaodong, Li, Jinyan, Liu, Huiqing, Pui, Ching-Hon, Evans, William E, Naeve, Clayton, Wong, Limsoon, Downing, James R

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Gene expression profiling of pediatric acute myelogenous leukemia von Ross, Mary E., Mahfouz, Rami, Onciu, Mihaela, Liu, Hsi-Che, Zhou, Xiaodong, Song, Guangchun, Shurtleff, Sheila A., Pounds, Stanley, Cheng, Cheng, Ma, Jing, Ribeiro, Raul C., Rubnitz, Jeffrey E., Girtman, Kevin, Williams, W. Kent, Raimondi, Susana C., Liang, Der-Cherng, Shih, Lee-Yung, Pui, Ching-Hon, Downing, James R.

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MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas von Tatevossian, Ruth G., Tang, Bo, Dalton, James, Forshew, Tim, Lawson, Andrew R., Ma, Jing, Neale, Geoff, Shurtleff, Sheila A., Bailey, Simon, Gajjar, Amar, Baker, Suzanne J., Sheer, Denise, Ellison, David W.

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Germline Mutations in Predisposition Genes in Pediatric Cancer von Zhang, Jinghui, Walsh, Michael F, Wu, Gang, Edmonson, Michael N, Gruber, Tanja A, Easton, John, Hedges, Dale, Ma, Xiaotu, Zhou, Xin, Yergeau, Donald A, Wilkinson, Mark R, Vadodaria, Bhavin, Chen, Xiang, McGee, Rose B, Hines-Dowell, Stacy, Nuccio, Regina, Quinn, Emily, Shurtleff, Sheila A, Rusch, Michael, Patel, Aman, Becksfort, Jared B, Wang, Shuoguo, Weaver, Meaghann S, Ding, Li, Mardis, Elaine R, Wilson, Richard K, Gajjar, Amar, Ellison, David W, Pappo, Alberto S, Pui, Ching-Hon, Nichols, Kim E, Downing, James R

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The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes von Huether, Robert, Dong, Li, Chen, Xiang, Wu, Gang, Parker, Matthew, Wei, Lei, Ma, Jing, Edmonson, Michael N., Hedlund, Erin K., Rusch, Michael C., Shurtleff, Sheila A., Mulder, Heather L., Boggs, Kristy, Vadordaria, Bhavin, Cheng, Jinjun, Yergeau, Donald, Song, Guangchun, Becksfort, Jared, Lemmon, Gordon, Weber, Catherine, Cai, Zhongling, Dang, Jinjun, Walsh, Michael, Gedman, Amanda L., Faber, Zachary, Easton, John, Gruber, Tanja, Kriwacki, Richard W., Partridge, Janet F., Ding, Li, Wilson, Richard K., Mardis, Elaine R., Mullighan, Charles G., Gilbertson, Richard J., Baker, Suzanne J., Zambetti, Gerard, Ellison, David W., Zhang, Jinghui, Downing, James R.

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BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros von Downing, James R, Mullighan, Charles G, Miller, Christopher B, Radtke, Ina, Phillips, Letha A, Dalton, James, Ma, Jing, White, Deborah, Hughes, Timothy P, Le Beau, Michelle M, Pui, Ching-Hon, Relling, Mary V, Shurtleff, Sheila A

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia von Shurtleff, Sheila A, Pui, Ching-Hon, Radtke, Ina, Mullighan, Charles G, Dalton, James D, Pounds, Stanley B, Evans, William E, Goorha, Salil, Girtman, Kevin, Su, Xiaoping, Relling, Mary V, Coustan-Smith, Elaine, Ma, Jing, Downing, James R, Mathew, Susan, Miller, Christopher B

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Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia von Mullighan, Charles G, Su, Xiaoping, Zhang, Jinghui, Radtke, Ina, Phillips, Letha A.A, Miller, Christopher B, Ma, Jing, Liu, Wei, Cheng, Cheng, Schulman, Brenda A, Harvey, Richard C, Chen, I-Ming, Clifford, Robert J, Carroll, William L, Reaman, Gregory, Bowman, W. Paul, Devidas, Meenakshi, Gerhard, Daniela S, Yang, Wenjian, Relling, Mary V, Shurtleff, Sheila A, Campana, Dario, Borowitz, Michael J, Pui, Ching-Hon, Smith, Malcolm, Hunger, Stephen P, Willman, Cheryl L, Downing, James R

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Diagnostic Utility of a Custom 34-Gene Anchored Multiplex PCR-Based Next-Generation Sequencing Fusion Panel for the Diagnosis of Bone and Soft Tissue Neoplasms With Identification... von Dermawan, Josephine K., Cheng, Yu Wei, Tu, Zheng Jin, Meyer, Anders, Habeeb, Omar, Zou, Youran, Goldblum, John R., Billings, Steven D., Kilpatrick, Scott E., Reith, John D., Shurtleff, Sheila A., Farkas, Daniel H., Rubin, Brian P., Azzato, Elizabeth M.

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Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells von SOMERVAILLE, Tim C. P, MATHENY, Christina J, SPENCER, Gary J, IWASAKI, Masayuki, RINN, John L, WITTEN, Daniela M, CHANG, Howard Y, SHURTLEFF, Sheila A, DOWNING, James R, CLEARY, Michael L

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Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia von van Oosterwijk, Jolieke G, Buelow, Daelynn R, Drenberg, Christina D, Vasilyeva, Aksana, Li, Lie, Shi, Lei, Wang, Yong-Dong, Finkelstein, David, Shurtleff, Sheila A, Janke, Laura J, Pounds, Stanley, Rubnitz, Jeffrey E, Inaba, Hiroto, Pabla, Navjotsingh, Baker, Sharyn D

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Chromosome arm 1q gain is an adverse prognostic factor in localized and diffuse leptomeningeal glioneuronal tumors with BRAF gene fusion and 1p deletion von Chiang, Jason, Dalton, James, Upadhyaya, Santhosh A., Patay, Zoltán, Qaddoumi, Ibrahim, Li, Xiaoyu, Segura, Annette D., Sharma, Suash, Ismail, Azzam, Shurtleff, Sheila A., Raimondi, Susana C.

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Genetic analysis of patients with defects in early B-cell development von Conley, Mary Ellen, Broides, Arnon, Hernandez-Trujillo, Vivian, Howard, Vanessa, Kanegane, Hirokazu, Miyawaki, Toshio, Shurtleff, Sheila A.

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