Parkinson's disease: genetics and pathogenesis von Shulman, Joshua M, De Jager, Philip L, Feany, Mel B

Volltext

Emerging links between pediatric lysosomal storage diseases and adult parkinsonism von Ysselstein, Daniel, Shulman, Joshua M., Krainc, Dimitri

Volltext

Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity von Yu, Meigen, Ye, Hui, De-Paula, Ruth B, Mangleburg, Carl Grant, Wu, Timothy, Lee, Tom V, Li, Yarong, Duong, Duc, Phillips, Bridget, Cruchaga, Carlos, Allen, Genevera I, Seyfried, Nicholas T, Al-Ramahi, Ismael, Botas, Juan, Shulman, Joshua M

Volltext

Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score von Yao, Tianyi, Sweeney, Elizabeth, Nagorski, John, Shulman, Joshua M., Allen, Genevera I.

Volltext

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease von Hsieh, Yi-Chen, Guo, Caiwei, Yalamanchili, Hari K., Abreha, Measho, Al-Ouran, Rami, Li, Yarong, Dammer, Eric B., Lah, James J., Levey, Allan I., Bennett, David A., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.

Volltext

A mitocentric view of Parkinson's disease von Haelterman, Nele A, Yoon, Wan Hee, Sandoval, Hector, Jaiswal, Manish, Shulman, Joshua M, Bellen, Hugo J

Volltext

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies von Ali, Yousuf O, Allen, Hunter M, Yu, Lei, Li-Kroeger, David, Bakhshizadehmahmoudi, Dena, Hatcher, Asante, McCabe, Cristin, Xu, Jishu, Bjorklund, Nicole, Taglialatela, Giulio, Bennett, David A, De Jager, Philip L, Shulman, Joshua M, Bellen, Hugo J, Lu, Hui-Chen

Volltext

Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits von Wangler, Michael F, Hu, Yanhui, Shulman, Joshua M

Volltext

Tau polarizes an aging transcriptional signature to excitatory neurons and glia von Wu, Timothy, Deger, Jennifer M, Ye, Hui, Guo, Caiwei, Dhindsa, Justin, Pekarek, Brandon T, Al-Ouran, Rami, Liu, Zhandong, Al-Ramahi, Ismael, Botas, Juan, Shulman, Joshua M

Volltext

Genetics and Pathogenesis of Parkinson's Syndrome von Ye, Hui, Robak, Laurie A, Yu, Meigen, Cykowski, Matthew, Shulman, Joshua M

Volltext

Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain von Ye, Hui, Ojelade, Shamsideen A., Li-Kroeger, David, Zuo, Zhongyuan, Wang, Liping, Li, Yarong, Gu, Jessica Y. J., Tepass, Ulrich, Rodal, Avital Adah, Bellen, Hugo J., Shulman, Joshua M.

Volltext

Integrated analysis of the aging brain transcriptome and proteome in tauopathy von Mangleburg, Carl Grant, Wu, Timothy, Yalamanchili, Hari K., Guo, Caiwei, Hsieh, Yi-Chen, Duong, Duc M., Dammer, Eric B., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.

Volltext

Genetic Modifiers of Tauopathy in Drosophila von Shulman, Joshua M, Feany, Mel B

Volltext

cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis von Ojelade, Shamsideen A., Lee, Tom V., Giagtzoglou, Nikolaos, Yu, Lei, Ugur, Berrak, Li, Yarong, Duraine, Lita, Zuo, Zhongyuan, Petyuk, Vlad, De Jager, Philip L., Bennett, David A., Arenkiel, Benjamin R., Bellen, Hugo J., Shulman, Joshua M.

Volltext

Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection von Raj, Towfique, Shulman, Joshua M., Keenan, Brendan T., Chibnik, Lori B., Evans, Denis A., Bennett, David A., Stranger, Barbara E., De Jager, Philip L.

Volltext

The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults von Valenca, Guilherme T, Srivastava, Gyan P, Oliveira-Filho, Jamary, White, Charles C, Yu, Lei, Schneider, Julie A, Buchman, Aron S, Shulman, Joshua M, Bennett, David A, De Jager, Philip L

Volltext

Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease von Robak, Laurie A, Jansen, Iris E, van Rooij, Jeroen, Uitterlinden, André G, Kraaij, Robert, Jankovic, Joseph, Heutink, Peter, Shulman, Joshua M

Volltext

Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease von Chouhan, Amit K, Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R, Bellen, Hugo J, Shulman, Joshua M

Volltext

Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling von Tree, David R.P., Shulman, Joshua M., Rousset, Raphaël, Scott, Matthew P., Gubb, David, Axelrod, Jeffrey D.

Volltext

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease von Guo, Qi, Dammer, Eric B., Zhou, Maotian, Kundinger, Sean R., Gearing, Marla, Lah, James J., Levey, Allan I., Shulman, Joshua M., Seyfried, Nicholas T.

Volltext