Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins von Pirazzini, Marco, Azarnia Tehran, Domenico, Zanetti, Giulia, Megighian, Aram, Scorzeto, Michele, Fillo, Silvia, Shone, Clifford C., Binz, Thomas, Rossetto, Ornella, Lista, Florigio, Montecucco, Cesare

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Molecular features of the sortase enzyme family von Bradshaw, William J, Davies, Abigail H, Chambers, Christopher J, Roberts, April K, Shone, Clifford C, Acharya, K. Ravi

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Super toxins from a super bug: structure and function of Clostridium difficile toxins von Davies, Abigail H, Roberts, April K, Shone, Clifford C, Acharya, K Ravi

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The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals von Pirazzini, Marco, Bordin, Fulvio, Rossetto, Ornella, Shone, Clifford C., Binz, Thomas, Montecucco, Cesare

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Double anchorage to the membrane and intact inter‐chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons von Pirazzini, Marco, Rossetto, Ornella, Bolognese, Paolo, Shone, Clifford C., Montecucco, Cesare

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A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Clostridioides difficile Infection in Pre-clinical Models von Roberts, April K., Harris, Hannah C., Smith, Michael, Giles, Joanna, Polak, Oktawia, Buckley, Anthony M., Clark, Emma, Ewin, Duncan, Moura, Ines B., Spitall, William, Shone, Clifford C., Wilcox, Mark, Chilton, Caroline, Donev, Rossen

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Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism von Zanetti, Giulia, Azarnia Tehran, Domenico, Pirazzini, Marcon, Binz, Thomas, Shone, Clifford C., Fillo, Silvia, Lista, Florigio, Rossetto, Ornella, Montecucco, Cesare

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Cwp84, a Surface-associated Cysteine Protease, Plays a Role in the Maturation of the Surface Layer of Clostridium difficile von Kirby, Jonathan M., Ahern, Helen, Roberts, April K., Kumar, Vivek, Freeman, Zoe, Acharya, K.Ravi, Shone, Clifford C.

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Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro von Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi

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A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins von Azarnia Tehran, Domenico, Zanetti, Giulia, Leka, Oneda, Lista, Florigio, Fillo, Silvia, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare, Paradisi, Cristina, Mattarei, Andrea, Pirazzini, Marco

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The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles von Pirazzini, Marco, Tehran, Domenico Azarnia, Zanetti, Giulia, Lista, Florigio, Binz, Thomas, Shone, Clifford C., Rossetto, Ornella, Montecucco, Cesare

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Structure and function of a Clostridium difficile sortase enzyme von Chambers, Christopher J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi

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Genomes of Escherichia coli bacteraemia isolates originating from urinary tract foci contain more virulence-associated genes than those from non-urinary foci and neutropaenic hosts von Dale, Adam P., Pandey, Anish K., Hesp, Richard J., Belogiannis, Konstantinos, Laver, Jay R., Shone, Clifford C., Read, Robert C.

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A family of killer toxins. Exploring the mechanism of ADP-ribosylating toxins von Holbourn, Kenneth P, Shone, Clifford C, Acharya, K R

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The structure of the S-layer of Clostridium difficile von Bradshaw, William J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi

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The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile von Bradshaw, William J., Kirby, Jonathan M., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi

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Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons von Pirazzini, Marco, Rossetto, Ornella, Bertasio, Cristina, Bordin, Fulvio, Shone, Clifford C., Binz, Thomas, Montecucco, Cesare

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Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile von Sundriyal, Amit, Roberts, April K., Shone, Clifford C., Acharya, K.Ravi

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Erratum to “Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism” [Biochem. Pharmacol. 98 (2015) 522–530]... von Zanetti, Giulia, Azarnia Tehran, Domenico, Pirazzini, Marco, Binz, Thomas, Shone, Clifford C., Fillo, Silvia, Lista, Florigio, Rossetto, Ornella, Montecucco, Cesare

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Development and Evaluation of an Ovine Antibody-Based Platform for Treatment of Clostridium difficile Infection von Roberts, April, McGlashan, Joanna, Al-Abdulla, Ibrahim, Ling, Roger, Denton, Harriet, Green, Steve, Coxon, Ruth, Landon, John, Shone, Clifford

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