Anti-angiogenesis therapy in cancer: Current challenges and future perspectives von Shojaei, Farbod

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Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells von Shojaei, Farbod, Ferrara, Napoleone

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G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models von Shojaei, Farbod, Wu, Xiumin, Qu, Xueping, Kowanetz, Marcin, Yu, Lanlan, Tan, Martha, Meng, Y. Gloria, Ferrara, Napoleone

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Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression von Shojaei, Farbod, Singh, Mallika, Thompson, Jennifer D, Ferrara, Napoleone

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Role of the microenvironment in tumor growth and in refractoriness/resistance to anti-angiogenic therapies von Shojaei, Farbod, Ferrara, Napoleone

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Tumor refractoriness to anti- VEGF treatment is mediated by CD11b + Gr1 + myeloid cells von Shojaei, Farbod, Ferrara, Napoleone, Wu, Xiumin, Malik, Ajay K, Zhong, Cuiling, Baldwin, Megan E, Schanz, Stefanie, Fuh, Germaine, Gerber, Hans-Peter

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The epigenetic immunomodulator, HBI-8000, enhances the response and reverses resistance to checkpoint inhibitors von Bissonnette, Reid P, Cesario, Rosemary M, Goodenow, Bob, Shojaei, Farbod, Gillings, Mireille

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HGF/c-Met acts as an alternative angiogenic pathway in sunitinib-resistant tumors von Shojaei, Farbod, Lee, Joseph H, Simmons, Brett H, Wong, Anthony, Esparza, Carlos O, Plumlee, Pamela A, Feng, Junli, Stewart, Albert E, Hu-Lowe, Dana D, Christensen, James G

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HBI-8000, HUYABIO Lead Clinical Program, Is a Selective Histone Deacetylase Inhibitor With Therapeutic Benefits in Leukemia and in Solid Tumors von Shojaei, Farbod, Goodenow, Bob, Lee, Gloria, Kabbinavar, Fairooz, Gillings, Mireille

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Antiangiogenic therapy for cancer: an update von Shojaei, Farbod, Ferrara, Napoleone

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HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis von Shojaei, Farbod, Simmons, Brett H, Lee, Joseph H, Lappin, Patrick B, Christensen, James G

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Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer von Shojaei, Farbod, Scott, Nathan, Kang, Xiaolin, Lappin, Patrick B, Fitzgerald, Amanda A, Karlicek, Shannon, Simmons, Brett H, Wu, Aidong, Lee, Joseph H, Bergqvist, Simon, Kraynov, Eugenia

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Hierarchical and Ontogenic Positions Serve to Define the Molecular Basis of Human Hematopoietic Stem Cell Behavior von Shojaei, Farbod, Trowbridge, Jennifer, Gallacher, Lisa, Yuefei, Lou, Goodale, David, Karanu, Francis, Levac, Krysta, Bhatia, Mickie

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Smad7 alters cell fate decisions of human hematopoietic repopulating cells von Chadwick, Kristin, Shojaei, Farbod, Gallacher, Lisa, Bhatia, Mickie

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Role of myeloid cells in tumor angiogenesis and growth von Shojaei, Farbod, Zhong, Cuiling, Wu, Xiumin, Yu, Lanlan, Ferrara, Napoleone

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Antiangiogenesis to treat cancer and intraocular neovascular disorders von Shojaei, Farbod, Ferrara, Napoleone

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Abstract C071: HBI-2375, a selective inhibitor of MLL1-WDR5 interaction, possesses desirable preclinical characteristics in solid tumors in combination with checkpoint inhibitors a... von Shojaei, Farbod, Fang, Che, Ricono, Jill M, Gillings, Mireille

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Bv8 regulates myeloid-cell-dependent tumour angiogenesis von Ferrara, Napoleone, Shojaei, Farbod, Wu, Xiumin, Zhong, Cuiling, Yu, Lanlan, Liang, Xiao-Huan, Yao, Jenny, Blanchard, Dominique, Bais, Carlos, Peale, Franklin V, van Bruggen, Nicholas, Ho, Calvin, Ross, Jed, Tan, Martha, Carano, Richard A. D, Meng, Y. Gloria

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Abstract A098: HBI-2376, HUYABIO clinical stage SHP2 inhibitor, displays efficacy signal in patients with KRAS mutations in early clinical studies von Shojaei, Farbod, Ricono, Jill M, Fang, Che, Xing, Yan, Ning, John, Lee, Gloria, Gillings, Mireille

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Abstract A097: HBI-2438, HUYABIO selective KRASG12C inhibitor with BBB penetration, inhibited tumor growth in a metastatic brain model as single agent and also displayed synergy in... von Shojaei, Farbod, Ricono, Jill M, Fang, Che, Ning, John, Lee, Gloria, Gillings, Mireille

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