Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models von SHOEMAKER, Alex R, MITTEN, Michael J, BAUCH, Joy, MARSH, Kennan, TAHIR, Steven K, XIUFENYANG, TSE, Christin, FESIK, Stephen W, ROSENBERG, Saul H, ELMORE, Steven W, ADICKES, Jessica, ACKLER, Scott, REFICI, Marion, FERGUSON, Debra, OLEKSIJEW, Anatol, O'CONNOR, Jacqueline M, BAOLE WANG, FROST, David J

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ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo von Ackler, Scott, Xiao, Yu, Mitten, Michael J, Foster, Kelly, Oleksijew, Anatol, Refici, Marion, Schlessinger, Sally, Wang, Baole, Chemburkar, Sanjay R, Bauch, Joy, Tse, Christin, Frost, David J, Fesik, Stephen W, Rosenberg, Saul H, Elmore, Steven W, Shoemaker, Alex R

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Hypoxia-Inducible Factor-1 Inhibition in Combination with Temozolomide Treatment Exhibits Robust Antitumor Efficacy In vivo von LEIMING LI, XIAOYU LIN, SHOEMAKER, Alex R, ALBERT, Daniel H, FESIK, Stephen W, YU SHEN

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The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity von Bromberg, Kenneth D, Mitchell, Taylor R H, Upadhyay, Anup K, Jakob, Clarissa G, Jhala, Manisha A, Comess, Kenneth M, Lasko, Loren M, Li, Conglei, Tuzon, Creighton T, Dai, Yujia, Li, Fengling, Eram, Mohammad S, Nuber, Alexander, Soni, Niru B, Manaves, Vlasios, Algire, Mikkel A, Sweis, Ramzi F, Torrent, Maricel, Schotta, Gunnar, Sun, Chaohong, Michaelides, Michael R, Shoemaker, Alex R, Arrowsmith, Cheryl H, Brown, Peter J, Santhakumar, Vijayaratnam, Martin, Alberto, Rice, Judd C, Chiang, Gary G, Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Pappano, William N

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The HPK1 Inhibitor A‑745 Verifies the Potential of Modulating T Cell Kinase Signaling for Immunotherapy von Malchow, Sven, Korepanova, Alla, Panchal, Sanjay C, McClure, Ryan A, Longenecker, Kenton L, Qiu, Wei, Zhao, Hongyu, Cheng, Min, Guo, Jun, Klinge, Kelly L, Trusk, Patricia, Pratt, Steven D, Li, Tao, Kurnick, Matthew D, Duan, Lishu, Shoemaker, Alex R, Gopalakrishnan, Sujatha M, Warder, Scott E, Shotwell, J. Brad, Lai, Albert, Sun, Chaohong, Osuma, Augustine T, Pappano, William N

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Tumor Regionality in the Mouse Intestine Reflects the Mechanism of Loss of Apc Function von Haigis, Kevin M., Hoff, Peter D., White, Alanna, Shoemaker, Alex R., Halberg, Richard B., Dove, William F.

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A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo von SHOEMAKER, Alex R, OLEKSIJEW, Anatol, MARSH, Kennan, MCCLELLAN, William, NELLANS, Hugh, NG, Shichung, NIMMER, Paul, O'CONNOR, Jacqueline M, OLTERSDORF, Tilman, WEIGUO QING, WANG SHEN, STAVROPOULOS, Jason, BAUCH, Joy, TAHIR, Stephen K, BAOLE WANG, WARNER, Robert, HAICHAO ZHANG, FESIK, Stephen W, ROSENBERG, Saul H, ELMORE, Steven W, BELLI, Barbara A, BORRE, Tony, BRUNCKO, Milan, DECKWIRTH, Thomas, FROST, David J, JARVIS, Ken, JOSEPH, Mary K

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PARP inhibitors attenuate chemotherapy-induced painful neuropathy von Brederson, Jill-Desiree, Joshi, Shailen K., Browman, Kaitlin E., Mikusa, Joseph, Zhong, Chengmin, Gauvin, Donna, Liu, Xuesong, Shi, Yan, Penning, Thomas D., Shoemaker, Alex R., Giranda, Vincent L.

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Studies of neoplasia in the Min mouse von Shoemaker, Alex R, Gould, Karen A, Luongo, Cindy, Moser, Amy R, Dove, William F

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N-ethyl-N-nitrosourea treatment of multiple intestinal neoplasia (Min) mice : age-related effects on the formation of intestinal adenomas : cystic crypts, and epidermoid cysts von SHOEMAKER, A. R, MOSER, A. R, DOVE, W. F

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Somatic mutational mechanisms involved in intestinal tumor formation in Min mice von SHOEMAKER, A. R, LUONGO, C, MOSER, A. R, MARTON, L. J, DOVE, W. F

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A Resistant Genetic Background Leading to Incomplete Penetrance of Intestinal Neoplasia and Reduced Loss of Heterozygosity in ApcMin/+ Mice von Shoemaker, Alex R., Moser, Amy R., Midgley, Carol A., Clipson, Linda, Newton, Michael A., Dove, William F.

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Manipulation of the mouse germline in the study ofMin-induced neoplasia von Bilger, Andrea, Shoemaker, Alex R., Gould, Karen A., Dove, William F.

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Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice von Shoemaker, A R, Haigis, K M, Baker, S M, Dudley, S, Liskay, R M, Dove, W F

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Homozygosity for the Minallele of Apc results in disruption of mouse development prior to gastrulation von Moser, Amy Rapaich, Shoemaker, Alex R., Connelly, Camille S., Clipson, Linda, Gould, Karen A., Luongo, Cindy, Dove, William F., Siggers, Pamela H., Gardner, Richard L.

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Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation von Moser, A R, Shoemaker, A R, Connelly, C S, Clipson, L, Gould, K A, Luongo, C, Dove, W F, Siggers, P H, Gardner, R L

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The Bcl-2 Family Inhibitor ABT-263 Shows Significant Anti-Tumor Efficacy in Models of B Cell Non-Hodgkin's Lymphoma von Shoemaker, Alex R., Mitten, Michael J., Oleksijew, Anatol, O'Connor, Jacqeuline M., Wang, Baole, Ackler, Scott, Joseph, Mary, Zhang, Haichao, Nimmer, Paul, Xiao, Yu, Tse, Christin, Frost, David J., Fesik, Stephen W., Rosenberg, Saul H., Elmore, Steven W.

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The Bcl-2 Family Inhibitor ABT-263 Shows Significant but Reversible Thrombocytopenia in Mice von Shoemaker, Alex R., Mitten, Michael J., Adickes, Jessica, Oleksijew, Anatol, Zhang, Haichao, Bauch, Joy, Marsh, Kennan, Frost, David J., Madar, David, Tse, Christin, Fesik, Stephen W., Rosenberg, Saul H., Elmore, Steven W.

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Manipulation of the mouse germline in the study of Min-induced neoplasia von Bilger, A, Shoemaker, A R, Gould, K A, Dove, W F

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Mlh1 deficiency enhances several phenotypes of ApcMin/+ mice von SHOEMAKER, A. R, HAIGIS, K. M, BAKER, S. M, DUDLEY, S, LISKAY, R. M, DOVE, W. F

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