Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways von Subramonian, Divya, Phanhthilath, Nikki, Rinehardt, Hannah, Flynn, Sean, Huo, Yuchen, Zhang, Jing, Messer, Karen, Mo, Qianxing, Huang, Shixia, Lesperance, Jacqueline, Zage, Peter E.

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CCR2 Chemokine Receptors Enhance Growth and Cell-Cycle Progression of Breast Cancer Cells through SRC and PKC Activation von Yao, Min, Fang, Wei, Smart, Curtis, Hu, Qingting, Huang, Shixia, Alvarez, Nehemiah, Fields, Patrick, Cheng, Nikki

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TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis von Singh, Ramesh, Karri, Dileep, Shen, Hong, Shao, Jiangyong, Dasgupta, Subhamoy, Huang, Shixia, Edwards, Dean P, Ittmann, Michael M, O'Malley, Bert W, Yi, Ping

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Targeting TGF-β for treatment of osteogenesis imperfecta von Song, I-Wen, Nagamani, Sandesh Cs, Nguyen, Dianne, Grafe, Ingo, Sutton, Vernon Reid, Gannon, Francis H, Munivez, Elda, Jiang, Ming-Ming, Tran, Alyssa, Wallace, Maegen, Esposito, Paul, Musaad, Salma, Strudthoff, Elizabeth, McGuire, Sharon, Thornton, Michele, Shenava, Vinitha, Rosenfeld, Scott, Huang, Shixia, Shypailo, Roman, Orwoll, Eric, Lee, Brendan

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Tamoxifen Resistance in Breast Tumors Is Driven by Growth Factor Receptor Signaling with Repression of Classic Estrogen Receptor Genomic Function von MASSARWEH, Suleiman, OSBORNE, C. Kent, CREIGHTON, Chad J, LANFANG QIN, TSIMELZON, Anna, SHIXIA HUANG, WEISS, Heidi, RIMAWI, Mothaffar, SCHIFF, Rachel

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Generation of an in vitro 3D PDAC stroma rich spheroid model von Ware, Matthew J, Keshishian, Vazrik, Law, Justin J, Ho, Jason C, Favela, Carlos A, Rees, Paul, Smith, Billie, Mohammad, Sayeeduddin, Hwang, Rosa F, Rajapakshe, Kimal, Coarfa, Cristian, Huang, Shixia, Edwards, Dean P, Corr, Stuart J, Godin, Biana, Curley, Steven A

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Metformin and an insulin/IGF-1 receptor inhibitor are synergistic in blocking growth of triple-negative breast cancer von Xue, Lei, Chen, Fengju, Yue, Fei, Camacho, Laura, Kothapalli, Sushma, Wei, Guanyun, Huang, Shixia, Mo, Qianxing, Ma, Fei, Li, Yi, Jiralerspong, Sao

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Estimation of leaf color variances of Cotinus coggygria based on geographic and environmental variables von Tan, Xing, Wu, Jiaojiao, Liu, Yun, Huang, Shixia, Gao, Lan, Zhang, Wen

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miR‐130b directly targets ARHGAP1 to drive activation of a metastatic CDC42‐PAK1‐AP1 positive feedback loop in Ewing sarcoma von Satterfield, Laura, Shuck, Ryan, Kurenbekova, Lyazat, Allen‐Rhoades, Wendy, Edwards, Dean, Huang, Shixia, Rajapakshe, Kimal, Coarfa, Cristian, Donehower, Lawrence A., Yustein, Jason T.

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Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers von Mundt, Filip, Rajput, Sandeep, Li, Shunqiang, Ruggles, Kelly V, Mooradian, Arshag D, Mertins, Philipp, Gillette, Michael A, Krug, Karsten, Guo, Zhanfang, Hoog, Jeremy, Erdmann-Gilmore, Petra, Primeau, Tina, Huang, Shixia, Edwards, Dean P, Wang, Xiaowei, Wang, Xuya, Kawaler, Emily, Mani, D R, Clauser, Karl R, Gao, Feng, Luo, Jingqin, Davies, Sherri R, Johnson, Gary L, Huang, Kuan-Lin, Yoon, Christopher J, Ding, Li, Fenyö, David, Ellis, Matthew J, Townsend, R Reid, Held, Jason M, Carr, Steven A, Ma, Cynthia X

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Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers von Kim, Jin-Ah, Tan, Ying, Wang, Xian, Cao, Xixi, Veeraraghavan, Jamunarani, Liang, Yulong, Edwards, Dean P., Huang, Shixia, Pan, Xuewen, Li, Kaiyi, Schiff, Rachel, Wang, Xiao-Song

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Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis von Creighton, Chad J, Casa, Angelo, Lazard, ZaWaunyka, Huang, Shixia, Tsimelzon, Anna, Hilsenbeck, Susan G, Osborne, Charles Kent, Lee, Adrian V

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Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage von Chang, Chi-Hsuan, Zhang, Mei, Rajapakshe, Kimal, Coarfa, Cristian, Edwards, Dean, Huang, Shixia, Rosen, Jeffrey M.

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CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer von Lee, Yu-Ju, Ho, Shiuh-Rong, Graves, Joshua D, Xiao, Yang, Huang, Shixia, Lin, Weei-Chin

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Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer von Haricharan, Svasti, Punturi, Nindo, Singh, Purba, Holloway, Kimberly R, Anurag, Meenakshi, Schmelz, Jacob, Schmidt, Cheryl, Lei, Jonathan T, Suman, Vera, Hunt, Kelly, Olson, Jr, John A, Hoog, Jeremy, Li, Shunqiang, Huang, Shixia, Edwards, Dean P, Kavuri, Shyam M, Bainbridge, Matthew N, Ma, Cynthia X, Ellis, Matthew J

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TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiothe... von Jayaraman, Padmini, Parikh, Falguni, Newton, Jared M., Hanoteau, Aurelie, Rivas, Charlotte, Krupar, Rosemarie, Rajapakshe, Kimal, Pathak, Ravi, Kanthaswamy, Kavin, MacLaren, Cassie, Huang, Shixia, Coarfa, Cristian, Spanos, Chad, Edwards, Dean P., Parihar, Robin, Sikora, Andrew G.

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Regulation of OsmiR156h through Alternative Polyadenylation Improves Grain Yield in Rice von Zhao, Meng, Liu, Binmei, Wu, Kun, Ye, Yafeng, Huang, Shixia, Wang, Shuansuo, Wang, Yi, Han, Ruixi, Liu, Qian, Fu, Xiangdong, Wu, Yuejin

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Dimethyl Sulfoxide Inhibits Bile Acid Synthesis in Healthy Mice but Does Not Protect Mice from Bile-Acid-Induced Liver Damage von Chen, Xi, Li, Huiqiao, Liu, Yu'e, Qi, Jing, Dong, Bingning, Huang, Shixia, Zhao, Shangang, Zhu, Yi

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Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy von Haricharan, Svasti, Dong, Jie, Hein, Sarah, Reddy, Jay P, Du, Zhijun, Toneff, Michael, Holloway, Kimberly, Hilsenbeck, Susan G, Huang, Shixia, Atkinson, Rachel, Woodward, Wendy, Jindal, Sonali, Borges, Virginia F, Gutierrez, Carolina, Zhang, Hong, Schedin, Pepper J, Osborne, C Kent, Tweardy, David J, Li, Yi

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Evidence That Transgenes Encoding Components of the Wnt Signaling Pathway Preferentially Induce Mammary Cancers from Progenitor Cells von Li, Yi, Welm, Bryan, Podsypanina, Katrina, Huang, Shixia, Chamorro, Mario, Zhang, Xiaomei, Rowlands, Tracey, Egeblad, Mikala, Cowin, Pam, Werb, Zena, Tan, Lee K., Rosen, Jeffrey M., Varmus, Harold E.

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