Comparative sensitivity of laboratory animals used for preclinical convulsion risk assessment to drug-induced convulsion von Shiotani, Motohiro, Seki, Yuki, Takano, Misato, Ishihara, Hiroki, Mikamoto, Masaki, Nozaki, Yoshitane, Maeda, Sanae, Taniguchi, Tomohiko, Miyamoto, Norimasa, Yoshinaga, Takashi, Asakura, Shoji

Volltext

Novel predictive approaches for drug-induced convulsions in non-human primates using machine learning and heart rate variability analysis von Kuga, Kazuhiro, Shiotani, Motohiro, Hori, Kentaro, Mizuno, Hiroshi, Matsushita, Yusaku, Ozaki, Harushige, Hayashi, Kohei, Kubo, Takatomi, Kano, Manabu

Volltext

Application of a compact magnetic resonance imaging system for toxicologic pathology: evaluation of lithium-pilocarpine-induced rat brain lesions von Taketa, Yoshikazu, Shiotani, Motohiro, Tsuru, Yoshiharu, Kotani, Sadaharu, Osada, Yoshihide, Fukushima, Tatsuto, Inomata, Akira, Hosokawa, Satoru

Volltext

Proteomic analysis for neuronal vacuolation induced by MK-801 in rat retrosplenial cortex von Shiotani, Motohiro, Nakano, Kyoko, Yamauchi, Emiko, Oda, Yoshiya, Hosokawa, Satoru, Aoki, Toyohiko

Volltext

EFFECT OF AUTONOMIC NERVOUS FUNCTION ON QT INTERVAL IN DOGS von HARADA, Takuma, ABE, Junko, SHIOTANI, Motohiro, HAMADA, Yoshimasa, HORII, Ikuo

Volltext

Nonclinical evaluation of abuse liability of the dual orexin receptor antagonist lemborexant von Asakura, Shoji, Shiotani, Motohiro, Gauvin, David V., Fujiwara, Atsushi, Ueno, Takashi, Bower, Nancy, Beuckmann, Carsten T., Moline, Margaret

Volltext

Methodological validation of an existing telemetry system for QT evaluation in conscious guinea pigs von Shiotani, Motohiro, Harada, Takuma, Abe, Junko, Hamada, Yoshimasa, Horii, Ikuo

Volltext

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis von Hong, W. David, Benayoud, Farid, Nixon, Gemma L., Ford, Louise, Johnston, Kelly L., Clare, Rachel H., Cassidy, Andrew, Cook, Darren A. N., Siu, Amy, Shiotani, Motohiro, Webborn, Peter J. H., Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J., Ehrens, Alexandra, Hübner, Marc P., Hoerauf, Achim, Roberts, Adam P., Hubbard, Alasdair T. M., Tate, Edward W., Serwa, Remigiusz A., Leung, Suet C., Qie, Li, Berry, Neil G., Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A., O’Neill, Paul M.

Volltext

PRACTICAL APPLICATION OF GUINEA PIG TELEMETRY SYSTEM FOR QT EVALUATION von SHIOTANI, Motohiro, HARADA, Takuma, ABE, Junko, SAWADA, Yasufusa, HASHIMOTO, Keitaro, HAMADA, Yoshimasa, HORII, Ikuo

Volltext

Neurobehavioral assessment of mice following repeated oral exposures to domoic acid during prenatal development von Shiotani, Motohiro, Cole, Toby B., Hong, Sungwoo, Park, Julie Ju Young, Griffith, William C., Burbacher, Thomas M., Workman, Tomomi, Costa, Lucio G., Faustman, Elaine M.

Volltext

Challenges in detection of premonitory electroencephalographic (EEG) changes of drug-induced seizure using a non-human primate EEG telemetry model von Shiotani, Motohiro, Nagano, Norihiro, Ishikawa, Akiyoshi, Sakai, Keita, Yoshinaga, Takashi, Kato, Hiroshi, Teramoto, Tetsuyuki, Furuya, Yoshiaki, Sawada, Kohei

Volltext

Oscillatory potentials in electroretinogram as an early marker of visual abnormalities in vitamin A deficiency von KAKIUCHI, DAI, UEHARA, TAISUKE, SHIOTANI, MOTOHIRO, NAKANO-ITO, KYOKO, SUGANUMA, AKIYOSHI, AOKI, TOYOHIKO, TSUKIDATE, KAZUO, SAWADA, KOHEI

Volltext

Application of a compact magnetic resonance imaging system for toxicologic pathology von Taketa, Yoshikazu, Shiotani, Motohiro, Tsuru, Yoshiharu, Kotani, Sadaharu, Osada, Yoshihide, Fukushima, Tatsuto, Inomata, Akira, Hosokawa, Satoru

Volltext

Prenatal exposure effects of repeated oral dose of domoic acid (DA) on neurobehavior in mice von Shiotani, Motohiro, Cole, Toby, Hong, Sungwoo, Griffith, William, Burbacher, Thomas, Costa, Lucio, Faustman, Elaine

Volltext

Aging-related changes of QT and RR intervals in conscious guinea pigs von Shiotani, Motohiro, Harada, Takuma, Abe, Junko, Hamada, Yoshimasa, Horii, Ikuo

Volltext

Molecular Properties of the Matrixprotein(M) Gene of the Lapinized Rinderpest Virus von SHIOTANI, Motohiro, MIURA, Ryuichi, FUJITA, Kentaro, WAKASA, Chiaki, UEMA, Masashi, KAI, Chieko

Volltext

Seroepidemiological survey of distemper virus infection in the Caspian Sea and in Lake Baikal von Ohashi, Kenjiro, Miyazaki, Nobuyuki, Tanabe, Shinsuke, Nakata, Haruhiko, Miura, Ryuichi, Fujita, Kentaro, Wakasa, Chiaki, Uema, Masashi, Shiotani, Motohiro, Takahashi, Eiji, Kai, Chieko

Volltext

Usefulness of Measuring QT Interval in Beagle Dogs with Chest Lead von HARADA, Takuma, SHIOTANI, Motohiro, ABE, Junko, HAMADA, Yoshimasa

Volltext

Usefulness of Measuring QT Interval in Beagle Dogs with Chest Lead von HARADA, Takuma, SHIOTANI, Motohiro, ABE, Junko, HAMADA, Yoshimasa

Volltext

胸部誘導によるビーグル犬の心電図QT間隔計測の有用性について von 原田, 拓真, 塩谷, 元宏, 阿部, 純子, 浜田, 悦昌

Volltext