Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency von Shin, Seula, Zhou, Hao, He, Chenxi, Wei, Yanjun, Wang, Yunfei, Shingu, Takashi, Zeng, Ailiang, Wang, Shaobo, Zhou, Xin, Li, Hongtao, Zhang, Qiang, Mo, Qinling, Long, Jiafu, Lan, Fei, Chen, Yiwen, Hu, Jian

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Glioma Stem Cells: Signaling, Microenvironment, and Therapy von Shin, Seul A., Ren, Jiangong, Zhou, Xin, Shingu, Takashi, Liebelt, Brandon D., Hu, Jian

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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis von Zhou, Xin, Shin, Seula, He, Chenxi, Zhang, Qiang, Rasband, Matthew N, Ren, Jiangong, Dai, Congxin, Zorrilla-Veloz, Rocío I, Shingu, Takashi, Yuan, Liang, Wang, Yunfei, Chen, Yiwen, Lan, Fei, Hu, Jian

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Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer von Inoue, Akira, Robinson, Frederick S., Minelli, Rosalba, Tomihara, Hideo, Rizi, Bahar Salimian, Rose, Johnathon L., Kodama, Takahiro, Srinivasan, Sanjana, Harris, Angela L., Zuniga, Andy M., Mullinax, Robert A., Ma, Xiaoyan, Seth, Sahil, Daniele, Joseph R., Peoples, Michael D., Loponte, Sara, Akdemir, Kadir C., Khor, Tin Oo, Feng, Ningping, Roszik, Jason, Sobieski, Mary M., Brunell, David, Stephan, Clifford, Giuliani, Virginia, Deem, Angela K., Shingu, Takashi, Deribe, Yonathan Lissanu, Menter, David G., Heffernan, Timothy P., Viale, Andrea, Bristow, Christopher A., Kopetz, Scott, Draetta, Giulio F., Genovese, Giannicola, Carugo, Alessandro

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Inhibition of autophagy at a late stage enhances imatinib‐induced cytotoxicity in human malignant glioma cells von Shingu, Takashi, Fujiwara, Keishi, Bögler, Oliver, Akiyama, Yasuhiko, Moritake, Kouzo, Shinojima, Naoki, Tamada, Yutaka, Yokoyama, Tomohisa, Kondo, Seiji

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Immune landscape of a genetically engineered murine model of glioma compared with human glioma von Zamler, Daniel B, Shingu, Takashi, Kahn, Laura M, Huntoon, Kristin, Kassab, Cynthia, Ott, Martina, Tomczak, Katarzyna, Liu, Jintan, Li, Yating, Lai, Ivy, Zorilla-Veloz, Rocio, Yee, Cassian, Rai, Kunal, Kim, Betty Ys, Watowich, Stephanie S, Heimberger, Amy B, Draetta, Giulio F, Hu, Jian

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Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3 von Aoki, Hiroshi, Kondo, Yasuko, Aldape, Kenneth, Yamamoto, Akitsugu, Iwado, Eiji, Yokoyama, Tomohisa, Hollingsworth, E. Faith, Kobayashi, Ryuji, Hess, Kenneth, Shinojima, Naoki, Shingu, Takashi, Tamada, Yutaka, Zhang, Li, Conrad, Charles, Bögler, Oliver, Mills, Gordon, Sawaya, Raymond, Kondo, Seiji

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Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma von Aksoy Yasar, Fatma Betul, Shingu, Takashi, Zamler, Daniel B., Zaman, Mohammad Fayyad, Chien, Derek Lin, Zhang, Qiang, Ren, Jiangong, Hu, Jian

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Abstract 1119: Quaking (Qki) loss enhances stemness of glioma stem cells through regulating intracellular vesicle trafficking system von Hu, Jian, Shingu, Takashi

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CBMT-17. DEFECTIVE QKI-DEPENDENT LIPID METABOLISM INDUCES GENOMIC INSTABILITY AND SENSITIZES GLIOBLASTOMA TO IMMUNOTHERAPY von Shingu, Takashi, Hu, Jian

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Stage-specific effect of inhibition of autophagy on chemotherapy-induced cytotoxicity von Shingu, Takashi, Fujiwara, Keishi, Bögler, Oliver, Akiyama, Yasuhiko, Moritake, Kouzo, Shinojima, Naoki, Tamada, Yutaka, Yokoyama, Tomohisa, Kondo, Seiji

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STEM-25. QUAKING (QKI) LOSS ENHANCES GSC STEMNESS AND PROMOTES GLIOMAGENESIS THROUGH REGULATING INTRACELLULAR VESICLE TRAFFICKING von Shingu, Takashi, Hu, Jian

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STMC-06. QKI DELETION ENHANCES SELF-RENEWAL OF GLIOMA STEM CELLS AND PROMOTES GLIOMAGENESIS von Hu, Jian, Shingu, Takashi

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Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells von Zhou, Yunfei, Zhou, Yan, Shingu, Takashi, Feng, Li, Chen, Zhao, Ogasawara, Marcia, Keating, Michael J., Kondo, Seiji, Huang, Peng

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Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis von Zhou, Yunfei, Zhou, Yan, Shingu, Takashi, Feng, Li, Chen, Zhao, Ogasawara, Marcia, Keating, Michael J, Kondo, Seiji, Huang, Peng

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TMIC-33. ARGINASE-1 AND ITS ROLE IN THE GLIOBLASTOMA MICROENVIRONMENT von Zamler, Daniel, Shingu, Takashi, Jiang, Shan, Yu, Fei, Jiang, Yingda, Draetta, Giulio, Hu, Jian

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Abstract 909: How glioma stem cells maintain stemness outside their niche von Hu, Jian, Shingu, Takashi, Yuan, Liang

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Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism von Zhou, Xin, He, Chenxi, Ren, Jiangong, Dai, Congxin, Stevens, Sharon R, Wang, Qianghu, Zamler, Daniel, Shingu, Takashi, Yuan, Liang, Chandregowda, Chythra R, Wang, Yunfei, Ravikumar, Visweswaran, Rao, Arvind Uk, Zhou, Feng, Zheng, Hongwu, Rasband, Matthew N, Chen, Yiwen, Lan, Fei, Heimberger, Amy B, Segal, Benjamin M, Hu, Jian

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Immune landscape of genetically-engineered murine models of glioma relative to human glioma by single-cell sequencing von Zamler, Daniel Bernard, Shingu, Takashi, Heimberger, Amy, Hu, Jian, Draetta, Giulio F.

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Qki is an essential regulator of microglial phagocytosis in demyelination von Ren, Jiangong, Dai, Congxin, Zhou, Xin, Barnes, Joseph A, Chen, Xi, Wang, Yunfei, Yuan, Liang, Shingu, Takashi, Heimberger, Amy B, Chen, Yiwen, Hu, Jian

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