Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands von Shibata, Norihito, Miyamoto, Naoki, Nagai, Katsunori, Shimokawa, Kenichiro, Sameshima, Tomoya, Ohoka, Nobumichi, Hattori, Takayuki, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs) von Ohoka, Nobumichi, Okuhira, Keiichiro, Ito, Masahiro, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Ujikawa, Osamu, Shimokawa, Kenichiro, Sano, Osamu, Koyama, Ryokichi, Fujita, Hisashi, Teratani, Mika, Matsumoto, Hirokazu, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER) von Ohoka, Nobumichi, Ujikawa, Osamu, Shimokawa, Kenichiro, Sameshima, Tomoya, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation von Shimokawa, Kenichiro, Shibata, Norihito, Sameshima, Tomoya, Miyamoto, Naoki, Ujikawa, Osamu, Nara, Hiroshi, Ohoka, Nobumichi, Hattori, Takayuki, Cho, Nobuo, Naito, Mikihiko

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Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase von Shibata, Norihito, Shimokawa, Kenichiro, Nagai, Katsunori, Ohoka, Nobumichi, Hattori, Takayuki, Miyamoto, Naoki, Ujikawa, Osamu, Sameshima, Tomoya, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Whole Structure−Activity Relationships of the Fat-Accumulation Inhibitor (−)-Ternatin: Recognition of the Importance of Each Amino Acid Residue von Shimokawa, Kenichiro, Iwase, Yoshiaki, Miwa, Ryoka, Yamada, Kaoru, Uemura, Daisuke

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Convergent synthesis and in vivo inhibitory effect on fat accumulation of (−)-ternatin, a highly N-methylated cyclic peptide von Shimokawa, Kenichiro, Yamada, Kaoru, Kita, Masaki, Uemura, Daisuke

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Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA von Ebara, Shunsuke, Yoshida, Misaki, Yamakawa, Hiroko, Shimokawa, Kenichiro, Inoue, Yasumichi, Tauchi, Hiroshi, Morishita, Daisuke

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Importance of the backbone conformation of (-)-ternatin in its fat-accumulation inhibitory activity against 3T3-L1 adipocytes von Shimokawa, Kenichiro, Miwa, Ryoka, Yamada, Kaoru, Uemura, Daisuke

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(−)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells von Ito, Masahiko, Ito, Junko, Kitazawa, Hidefumi, Shimamura, Ken, Fukami, Takehiro, Tokita, Shigeru, Shimokawa, Kenichiro, Yamada, Kaoru, Kanatani, Akio, Uemura, Daisuke

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Design, synthesis, and biological evaluation of biotin-labeled (−)-ternatin, a potent fat-accumulation inhibitor against 3T3-L1 adipocytes von Shimokawa, Kenichiro, Yamada, Kaoru, Ohno, Osamu, Oba, Yuichi, Uemura, Daisuke

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Application of FITC-labeled Ternatin on Its Cellular Localization in 3T3-L1 Murine Preadipocytes von Shimokawa, Kenichiro, Ohno, Osamu, Yamada, Kaoru, Oba, Yuichi, Uemura, Daisuke

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Biological Activity, Structural Features, and Synthetic Studies of (−)-Ternatin, a Potent Fat-Accumulation Inhibitor of 3T3-L1 Adipocytes von Shimokawa, Kenichiro, Mashima, Itsuka, Asai, Akiko, Ohno, Tomohiro, Yamada, Kaoru, Kita, Masaki, Uemura, Daisuke

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Second-Generation AUTACs for Targeted Autophagic Degradation von Takahashi, Daiki, Ora, Taiichi, Sasaki, Shigekazu, Ishii, Naoki, Tanaka, Toshio, Matsuda, Takumi, Ikeda, Mutsuki, Moriyama, Jun, Cho, Nobuo, Nara, Hiroshi, Maezaki, Hironobu, Kamaura, Masahiro, Shimokawa, Kenichiro, Arimoto, Hirokazu

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Phosphorylation Dynamics and Kinase Interaction in mRNA Transcription-Associated Kinases: Autophosphorylation of CDK12 and its Modulation by CDK7 and CDK9 von Yamakawa, Hiroko, Ebara, Shunsuke, Yoshida, Misaki, Yamamoto, Koji, Hayashi, Kozo, Shimokawa, Kenichiro, Araki, Shinsuke, Tauchi, Hiroshi, Morishita, Daisuke

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Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER) von Ohoka, Nobumichi, Ujikawa, Osamu, Shimokawa, Kenichiro, Sameshima, Tomoya, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation von Ohoka, Nobumichi, Morita, Yoko, Nagai, Katsunori, Shimokawa, Kenichiro, Ujikawa, Osamu, Fujimori, Ikuo, Ito, Masahiro, Hayase, Youji, Okuhira, Keiichiro, Shibata, Norihito, Hattori, Takayuki, Sameshima, Tomoya, Sano, Osamu, Koyama, Ryokichi, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Concise synthesis of a highly functionalized cyclopentane segment: toward the total synthesis of kansuinine A von Shimokawa, Kenichiro, Takamura, Hiroyoshi, Uemura, Daisuke

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Fragment-based drug discovery of potent and selective MKK3/6 inhibitors von Adams, Mark, Kobayashi, Toshitake, Lawson, J. David, Saitoh, Morihisa, Shimokawa, Kenichiro, Bigi, Simone V., Hixon, Mark S., Smith, Christopher R., Tatamiya, Takayuki, Goto, Masayuki, Russo, Joseph, Grimshaw, Charles E., Swann, Steven

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Structure-based hybridization of the bioactive natural products rhizonin A and ternatin leading to a selective fat-accumulation inhibitor against 3T3-L1 adipocytes von Shimokawa, Kenichiro, Yamada, Kaoru, Uemura, Daisuke

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