A chemical toolbox for the study of bromodomains and epigenetic signaling von Wu, Qin, Heidenreich, David, Zhou, Stanley, Ackloo, Suzanne, Krämer, Andreas, Nakka, Kiran, Lima-Fernandes, Evelyne, Deblois, Genevieve, Duan, Shili, Vellanki, Ravi N., Li, Fengling, Vedadi, Masoud, Dilworth, Jeffrey, Lupien, Mathieu, Brennan, Paul E., Arrowsmith, Cheryl H., Müller, Susanne, Fedorov, Oleg, Filippakopoulos, Panagis, Knapp, Stefan

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GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer von Wu, Qin, ba-alawi, Wail, Deblois, Genevieve, Cruickshank, Jennifer, Duan, Shili, Lima-Fernandes, Evelyne, Haight, Jillian, Tonekaboni, Seyed Ali Madani, Fortier, Anne-Marie, Kuasne, Hellen, McKee, Trevor D., Mahmoud, Hassan, Kushida, Michelle, Cameron, Sarina, Dogan-Artun, Nergiz, Chen, WenJun, Nie, Yan, Zhang, Lan Xin, Vellanki, Ravi N., Zhou, Stanley, Prinos, Panagiotis, Wouters, Bradly G., Dirks, Peter B., Done, Susan J., Park, Morag, Cescon, David W., Haibe-Kains, Benjamin, Lupien, Mathieu, Arrowsmith, Cheryl H.

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Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells von Lima-Fernandes, Evelyne, Murison, Alex, da Silva Medina, Tiago, Wang, Yadong, Ma, Anqi, Leung, Cherry, Luciani, Genna M., Haynes, Jennifer, Pollett, Aaron, Zeller, Constanze, Duan, Shili, Kreso, Antonija, Barsyte-Lovejoy, Dalia, Wouters, Bradly G., Jin, Jian, Carvalho, Daniel D. De, Lupien, Mathieu, Arrowsmith, Cheryl H., O’Brien, Catherine A.

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Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1 von Walker, John R, Duan, Shili, Dhe-Paganon, Sirano, Avvakumov, George V, Li, Yanjun, Arrowsmith, Cheryl H, Xue, Sheng, Bronner, Christian

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PRMT inhibition induces a viral mimicry response in triple-negative breast cancer von Wu, Qin, Nie, David Y., Ba-alawi, Wail, Ji, YiShuai, Zhang, ZiWen, Cruickshank, Jennifer, Haight, Jillian, Ciamponi, Felipe E., Chen, Jocelyn, Duan, Shili, Shen, Yudao, Liu, Jing, Marhon, Sajid A., Mehdipour, Parinaz, Szewczyk, Magdalena M., Dogan-Artun, Nergiz, Chen, WenJun, Zhang, Lan Xin, Deblois, Genevieve, Prinos, Panagiotis, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Jin, Jian, De Carvalho, Daniel D., Haibe-Kains, Benjamin, Wang, XiaoJia, Cescon, David W., Lupien, Mathieu, Arrowsmith, Cheryl H.

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Recognition and Specificity Determinants of the Human Cbx Chromodomains von Kaustov, Lilia, Ouyang, Hui, Amaya, Maria, Lemak, Alexander, Nady, Nataliya, Duan, Shili, Wasney, Gregory A., Li, Zhihong, Vedadi, Masoud, Schapira, Matthieu, Min, Jinrong, Arrowsmith, Cheryl H.

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Structure of the catalytic domain of EZH2 reveals conformational plasticity in cofactor and substrate binding sites and explains oncogenic mutations von Wu, Hong, Zeng, Hong, Dong, Aiping, Li, Fengling, He, Hao, Senisterra, Guillermo, Seitova, Alma, Duan, Shili, Brown, Peter J, Vedadi, Masoud, Arrowsmith, Cheryl H, Schapira, Matthieu

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Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex von Ivanochko, Danton, Halabelian, Levon, Henderson, Elizabeth, Savitsky, Pavel, Jain, Harshika, Marcon, Edyta, Duan, Shili, Hutchinson, Ashley, Seitova, Alma, Barsyte-Lovejoy, Dalia, Filippakopoulos, Panagis, Greenblatt, Jack, Lima-Fernandes, Evelyne, Arrowsmith, Cheryl H

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Cbx2 Targets PRC1 to Constitutive Heterochromatin in Mouse Zygotes in a Parent-of-Origin-Dependent Manner von Tardat, Mathieu, Albert, Mareike, Kunzmann, Rico, Liu, Zichuan, Kaustov, Lilia, Thierry, Raphael, Duan, Shili, Brykczynska, Urszula, Arrowsmith, Cheryl H., Peters, Antoine H.F.M.

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The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage von Kitevski-LeBlanc, Julianne, Fradet-Turcotte, Amélie, Kukic, Predrag, Wilson, Marcus D, Portella, Guillem, Yuwen, Tairan, Panier, Stephanie, Duan, Shili, Canny, Marella D, van Ingen, Hugo, Arrowsmith, Cheryl H, Rubinstein, John L, Vendruscolo, Michele, Durocher, Daniel, Kay, Lewis E

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Conformational dynamics of the TTD–PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability von Houliston, R. Scott, Lemak, Alexander, Iqbal, Aman, Ivanochko, Danton, Duan, Shili, Kaustov, Lilia, Ong, Michelle S., Fan, Lixin, Senisterra, Guillermo, Brown, Peter J., Wang, Yun-Xing, Arrowsmith, Cheryl H.

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An Integrative Proteomic Approach Identifies Novel Cellular SMYD2 Substrates von Ahmed, Hazem, Duan, Shili, Arrowsmith, Cheryl H, Barsyte-Lovejoy, Dalia, Schapira, Matthieu

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Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1 von Tauber, Maria, Kreuz, Sarah, Lemak, Alexander, Mandal, Papita, Yerkesh, Zhadyra, Veluchamy, Alaguraj, Al-Gashgari, Bothayna, Aljahani, Abrar, Cortés-Medina, Lorena V, Azhibek, Dulat, Fan, Lixin, Ong, Michelle S, Duan, Shili, Houliston, Scott, Arrowsmith, Cheryl H, Fischle, Wolfgang

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Molecular recognition of p53 and MDM2 by USP7/HAUSP von Frappier, Lori, Sheng, Yi, Saridakis, Vivian, Sarkari, Feroz, Duan, Shili, Wu, Tianne, Arrowsmith, Cheryl H

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Histone Recognition by Human Malignant Brain Tumor Domains von Nady, Nataliya, Krichevsky, Liubov, Zhong, Nan, Duan, Shili, Tempel, Wolfram, Amaya, Maria F., Ravichandran, Mani, Arrowsmith, Cheryl H.

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Molecular basis of Pirh2-mediated p53 ubiquitylation von Sheng, Yi, Laister, Rob C, Wu, Bin, Lukin, Jonathan, Srisailam, Sampath, Lemak, Alexander, Sunnerhagen, Maria, Benchimol, Sam, Arrowsmith, Cheryl H, Karra, Murthy, Tai, Elizabeth, Duan, Shili

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Role of Pirh2 in mediating the regulation of p53 and c-Myc von Hakem, Anne, Bohgaki, Miyuki, Lemmers, Bénédicte, Tai, Elisabeth, Salmena, Leonardo, Matysiak-Zablocki, Elzbieta, Jung, Yong-Sam, Karaskova, Jana, Kaustov, Lilia, Duan, Shili, Madore, Jason, Boutros, Paul, Sheng, Yi, Chesi, Marta, Bergsagel, P Leif, Perez-Ordonez, Bayardo, Mes-Masson, Anne-Marie, Penn, Linda, Squire, Jeremy, Chen, Xinbin, Jurisica, Igor, Arrowsmith, Cheryl, Sanchez, Otto, Benchimol, Samuel, Hakem, Razqallah

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Structural and Functional Comparison of the RING Domains of Two p53 E3 Ligases, Mdm2 and Pirh2 von Shloush, Jonathan, Vlassov, John E., Engson, Ian, Duan, Shili, Saridakis, Vivian, Dhe-paganon, Sirano, Raught, Brian, Sheng, Yi, Arrowsmith, Cheryl H.

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The Conserved CPH Domains of Cul7 and PARC Are Protein-Protein Interaction Modules That Bind the Tetramerization Domain of p53 von Kaustov, Lilia, Lukin, Jonathan, Lemak, Alexander, Duan, Shili, Ho, Melissa, Doherty, Ryan, Penn, Linda Z., Arrowsmith, Cheryl H.

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Characterization of a family of vacuolar Na + /H + antiporters in Arabidopsis thaliana von Aharon, Gilad S., Apse, Maris P., Duan, Shili, Hua, Xuejun, Blumwald, Eduardo

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