mTOR Signaling in Metabolism and Cancer von Huang, Shile

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Host Immune Response to Influenza A Virus Infection von Chen, Xiaoyong, Liu, Shasha, Goraya, Mohsan Ullah, Maarouf, Mohamed, Huang, Shile, Chen, Ji-Long

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Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5 von Chen, Long, Liu, Lei, Huang, Shile

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Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways von Shang, Chaowei, Zhou, Hongyu, Liu, Wang, Shen, Tao, Luo, Yan, Huang, Shile

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Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth von Shekoohi, Sahar, Rajasekaran, Santhanasabapathy, Patel, Dhaval, Yang, Shu, Liu, Wang, Huang, Shile, Yu, Xiuping, Witt, Stephan N.

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The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression von Xiong, Yu, Li, Linli, Zhang, Liting, Cui, Yangyang, Wu, Chengyong, Li, Hui, Chen, Kai, Yang, Qiuyuan, Xiang, Rong, Hu, Yiguo, Huang, Shile, Wei, Yuquan, Yang, Shengyong

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Newly synthesized Mpro inhibitors as potential oral anti-SARS-CoV-2 agents von Li, Lin, Huang, Shile

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A new clue to explain resistance to mTOR inhibitors von Huang, Shile

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MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis von Chen, Long, Liu, Lei, Luo, Yan, Huang, Shile

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Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation von Pan, Yanhong, Wang, Wei, Huang, Shuai, Ni, Wenting, Wei, Zhonghong, Cao, Yuzhu, Yu, Suyun, Jia, Qi, Wu, Yuanyuan, Chai, Chuan, Zheng, Qian, Zhang, Lei, Wang, Aiyun, Sun, Zhiguang, Huang, Shile, Wang, Shijun, Chen, Wenxing, Lu, Yin

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Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease von Xu, Yijiao, Liu, Chunxiao, Chen, Sujuan, Ye, Yangjing, Guo, Min, Ren, Qian, Liu, Lei, Zhang, Hai, Xu, Chong, Zhou, Qian, Huang, Shile, Chen, Long

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Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death von Chen, Long, Xu, Baoshan, Liu, Lei, Luo, Yan, Zhou, Hongyu, Chen, Wenxing, Shen, Tao, Han, Xiuzhen, Kontos, Christopher D., Huang, Shile

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Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A von Xu, Chong, Wang, Xiaoxue, Zhu, Yu, Dong, Xiaoqing, Liu, Chunxiao, Zhang, Hai, Liu, Lei, Huang, Shile, Chen, Long

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TRIM21 Promotes Rabies Virus Production by Degrading IRF7 through Ubiquitination von Zhang, Boyue, Cai, Ting, He, Hongling, Huang, Xuezhe, Chen, Guie, Lai, Yanqin, Luo, Yongwen, Huang, Shile, Luo, Jun, Guo, Xiaofeng

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Robust expression of vault RNAs induced by influenza A virus plays a critical role in suppression of PKR-mediated innate immunity von Li, Fang, Chen, Yuhai, Zhang, Zhaoyuan, Ouyang, Jing, Wang, Yi, Yan, Ruoxiang, Huang, Shile, Gao, George Fu, Guo, Guijie, Chen, Ji-Long

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Cadmium Impairs Autophagy Leading to Apoptosis by Ca2+-Dependent Activation of JNK Signaling Pathway in Neuronal Cells von Xu, Chong, Chen, Sujuan, Xu, Ming, Chen, Xiaoling, Wang, Xiaoxue, Zhang, Hai, Dong, Xiaoqing, Zhang, Ruijie, Chen, Xin, Gao, Wei, Huang, Shile, Chen, Long

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Loss of tumor suppressor menin expression in high grade cholangiocarcinomas von Lairmore, Terry C, Abdulsattar, Jehan, De Benedetti, Arrigo, Shi, Runhua, Huang, Shile, Khalil, Md Imtiaz, Witt, Stephan N

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Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy von Chamcheu, Jean Christopher, Roy, Tithi, Uddin, Mohammad Burhan, Banang-Mbeumi, Sergette, Chamcheu, Roxane-Cherille N, Walker, Anthony L, Liu, Yong-Yu, Huang, Shile

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Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network von Xu, Baoshan, Chen, Sujuan, Luo, Yan, Chen, Zi, Liu, Lei, Zhou, Hongyu, Chen, Wenxing, Shen, Tao, Han, Xiuzhen, Chen, Long, Huang, Shile

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Inhibition of Chk1 with Prexasertib Enhances the Anticancer Activity of Ciclopirox in Non-Small Cell Lung Cancer Cells von Huang, Zhu, Li, Wenjing, Wu, Yan, Cheng, Bing, Huang, Shile

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