BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor von Ozer, Hatice Gulcin, El-Gamal, Dalia, Powell, Ben, Hing, Zachary A, Blachly, James S, Harrington, Bonnie, Mitchell, Shaneice, Grieselhuber, Nicole R, Williams, Katie, Lai, Tzung-Huei, Alinari, Lapo, Baiocchi, Robert A, Brinton, Lindsey, Baskin, Elizabeth, Cannon, Matthew, Beaver, Larry, Goettl, Virginia M, Lucas, David M, Woyach, Jennifer A, Sampath, Deepa, Lehman, Amy M, Yu, Lianbo, Zhang, Jiazhong, Ma, Yan, Zhang, Ying, Spevak, Wayne, Shi, Songyuan, Severson, Paul, Shellooe, Rafe, Carias, Heidi, Tsang, Garson, Dong, Ken, Ewing, Todd, Marimuthu, Adhirai, Tantoy, Christina, Walters, Jason, Sanftner, Laura, Rezaei, Hamid, Nespi, Marika, Matusow, Bernice, Habets, Gaston, Ibrahim, Prabha, Zhang, Chao, Mathé, Ewy A, Bollag, Gideon, Byrd, John C, Lapalombella, Rosa

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Expanding the CRISPR/Cas genome-editing scope in Xenopus tropicalis von Shi, Zhaoying, Jiang, Hao, Liu, Guanghui, Shi, Songyuan, Zhang, Xuan, Chen, Yonglong

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Activation of P53 pathway contributes to Xenopus hybrid inviability von Shi, Zhaoying, Liu, Guanghui, Jiang, Hao, Shi, Songyuan, Zhang, Xuan, Deng, Yi, Chen, Yonglong

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Dual-parameter combined measurement sensor based on tri-metal structure von Teng, Yuntian, Shi, Songyuan, Qiu, Zhongchao, Pei, Fengxin, Zhang, Peng

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RAF inhibitors that evade paradoxical MAPK pathway activation von Zhang, Chao, Spevak, Wayne, Zhang, Ying, Burton, Elizabeth A., Ma, Yan, Habets, Gaston, Zhang, Jiazhong, Lin, Jack, Ewing, Todd, Matusow, Bernice, Tsang, Garson, Marimuthu, Adhirai, Cho, Hanna, Wu, Guoxian, Wang, Weiru, Fong, Daniel, Nguyen, Hoa, Shi, Songyuan, Womack, Patrick, Nespi, Marika, Shellooe, Rafe, Carias, Heidi, Powell, Ben, Light, Emily, Sanftner, Laura, Walters, Jason, Tsai, James, West, Brian L., Visor, Gary, Rezaei, Hamid, Lin, Paul S., Nolop, Keith, Ibrahim, Prabha N., Hirth, Peter, Bollag, Gideon

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Design, Synthesis, and Structure−Activity Relationships of Novel Insulin Receptor Tyrosine Kinase Activators von Lum, Robert T, Cheng, Mingshan, Cristobal, Cristina P, Goldfine, Ira D, Evans, Joseph L, Keck, James G, Macsata, Robert W, Manchem, Vara Prasad, Matsumoto, Yukiharu, Park, Sophia J, Rao, Sandhya S, Robinson, Louise, Shi, Songyuan, Spevak, Wayne R, Schow, Steven R

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Modeling human point mutation diseases in Xenopus tropicalis with a modified CRISPR/Cas9 system von Shi, Zhaoying, Xin, Huhu, Tian, Dandan, Lian, Jingru, Wang, Jianhui, Liu, Guanghui, Ran, Rensen, Shi, Songyuan, Zhang, Zixuan, Shi, Yu, Deng, Yi, Hou, Chunhui, Chen, Yonglong

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5-Substituted isophthalamides as insulin receptor sensitizers von Robinson, Louise, Bajjalieh, Sonia, Cairns, Nicholas, Lum, Robert T., Macsata, Robert W., Manchem, Vara Prasad, Park, Sophia J., Rao, Sandhya, Schow, Steven R., Shi, Songyuan, Spevak, Wayne R.

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A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo von VARA PRASAD MANCHEM, GOLDFINE, Ira D, VILLAR, Hugo O, WICK, Michael M, KOZLOWSKI, Michael R, KOHANSKI, Ronald A, CRISTOBAL, Cristina P, LUM, Robert T, SCHOW, Steven R, SHI, Songyuan, SPEVAK, Wayne R, LABORDE, Edgardo, TOAVS, Deborah K

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Regulation of Insulin Receptor Function by a Small Molecule Insulin Receptor Activator von Pender, Celia, Goldfine, Ira D, Manchem, Vara Prasad, Evans, Joseph L, Spevak, Wayne R, Shi, Songyuan, Rao, Sandhya, Bajjalieh, Sonia, Maddux, Betty A, Youngren, Jack F

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Abstract 553: Discovery of novel TRK/FMS dual inhibitors as therapeutic candidates for pancreatic cancer von Tsai, James, Zhang, Jiazhong, West, Brian L., Wong, Bernice, Burton, Betsy, Habets, Gaston, Marimuthu, Adhirai, Light, Emily, Powell, Ben, Shellooe, Rafe, Carias, Heidi, Shi, Songyuan, Spevak, Wayne, Nguyen, Hoa, Tsang, Garson, Zhang, Ying, Ewing, Todd, Zhang, Chao, Ibrahim, Prabha, Bollag, Gideon

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Abstract A229: BRAF inhibitors upregulate EGFR ligands: A molecular link to RAF inhibitor-induced cutaneous squamous cell carcinomas von Ma, Yan, Zhang, Chao, Habets, Gaston, Burton, Elizabeth A., Wong, Bernice, Nguyen, Hoa, Spevak, Wayne, zhang, Jiazhong, Cho, Hanna, Wu, Guoxian, Lin, Jack L., Ewing, Todd, Zhang, Ying, Shi, Songyuan, Nespi, Marika, Tsang, Garson, Marimuthu, Adhirai, Light, Emily, Powell, Ben, Shellooe, Rafe, Tsai, James, West, Brian L., Ibrahim, Prabha N., Hirth, Peter, Bollag, Gideon

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HETEROCYCLIC COMPOUNDS AND THEIR USES IN MODULATING BROMODOMAIN AND FOR TREATING DISEASES OR CONDITIONS RELEVANT THERETO von SHI, SONGYUAN, ZHANG, JIAZHONG, SPEVAK, WAYNE

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Heterocyclic compounds and uses thereof von Zhang, Jiazhong, Ibrahim, Prabha N, Spevak, Wayne, Ma, Yan, Powell, Ben, Shi, Songyuan

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Heterocyclic compounds and uses thereof von Zhang, Jiazhong, Spevak, Wayne, Shi, Songyuan

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Method for preparing whole genome R-loop sequencing library von SHI ZHAOYING, SHI SONGYUAN, CHEN YONGLONG

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HETEROCYCLIC COMPOUNDS AND USES THEREOF von ZHANG, Jiazhong, SPEVAK, Wayne, SHI, Songyuan

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HETEROCYCLIC COMPOUNDS AND USES THEREOF von ZHANG, JIAZHONG, SHI, SONGYUAN, POWELL, BEN, MA, YAN, SPEVAK, WAYNE, IBRAHIM, PRABHA N

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HETEROCYCLIC COMPOUNDS AND USES THEREOF von POWELL, Ben, ZHANG, Jiazhong, SPEVAK, Wayne, IBRAHIM, Prabha N, SHI, Songyuan, MA, Yan

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Compounds and methods for CD73 modulation and indications therefor von Buell, John, Zhang, Chao, Zhang, Jiazhong, Spevak, Wayne, Vander Wal, Mark, Walleshauser, Jack, Shi, Songyuan, Guo, Zuojun, Ly, Cuong

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