Targeting CDK4 and CDK6: From Discovery to Therapy von Sherr, Charles J, Beach, David, Shapiro, Geoffrey I

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NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination von Ruscetti, Marcus, Leibold, Josef, Bott, Matthew J, Fennell, Myles, Kulick, Amanda, Salgado, Nelson R, Chen, Chi-Chao, Ho, Yu-Jui, Sanchez-Rivera, Francisco J, Feucht, Judith, Baslan, Timour, Tian, Sha, Chen, Hsuan-An, Romesser, Paul B, Poirier, John T, Rudin, Charles M, de Stanchina, Elisa, Manchado, Eusebio, Sherr, Charles J, Lowe, Scott W

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CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma von Huang, Chun-Hao, Lujambio, Amaia, Zuber, Johannes, Tschaharganeh, Darjus F, Doran, Michael G, Evans, Michael J, Kitzing, Thomas, Zhu, Nan, de Stanchina, Elisa, Sawyers, Charles L, Armstrong, Scott A, Lewis, Jason S, Sherr, Charles J, Lowe, Scott W

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Forging a signature of in vivo senescence von Sharpless, Norman E., Sherr, Charles J.

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Physical and Functional Interactions of the Arf Tumor Suppressor Protein with Nucleophosmin/B23 von Bertwistle, David, Sugimoto, Masataka, Sherr, Charles J.

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Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia von Williams, Richard T, den Besten, Willem, Sherr, Charles J

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Cancer Cell Cycles von Sherr, Charles J.

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Divorcing ARF and p53: an unsettled case von Sherr, Charles J

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Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells von Li, Chunliang, Finkelstein, David, Sherr, Charles J

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Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma von Vo, BaoHan T., Li, Chunliang, Morgan, Marc A., Theurillat, Ilan, Finkelstein, David, Wright, Shaela, Hyle, Judith, Smith, Stephanie M.C., Fan, Yiping, Wang, Yong-Dong, Wu, Gang, Orr, Brent A., Northcott, Paul A., Shilatifard, Ali, Sherr, Charles J., Roussel, Martine F.

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Arf Gene Loss Enhances Oncogenicity and Limits Imatinib Response in Mouse Models of Bcr-Abl-Induced Acute Lymphoblastic Leukemia von Williams, Richard T., Roussel, Martine F., Sherr, Charles J.

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Surprising regulation of cell cycle entry von Sherr, Charles J

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Nucleolar Arf sequesters Mdm2 and activates p53 von Weber, Jason D., Taylor, Laura J., Roussel, Martine F., Sherr, Charles J., Bar-Sagi, Dafna

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Mouse medulloblastoma driven by CRISPR activation of cellular Myc von Vo, BaoHan T., Kwon, Jin Ah, Li, Chunliang, Finkelstein, David, Xu, Beisi, Orr, Brent A., Sherr, Charles J., Roussel, Martine F.

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Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL von Mullighan, Charles G, Williams, Richard T, Downing, James R, Sherr, Charles J

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Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells von Churchman, Michelle L, Roig, Ignasi, Jasin, Maria, Keeney, Scott, Sherr, Charles J

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Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome–positive acute lymphoblastic leukem... von Boulos, Nidal, Mulder, Heather L., Calabrese, Christopher R., Morrison, Jeffrey B., Rehg, Jerold E., Relling, Mary V., Sherr, Charles J., Williams, Richard T.

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Sumoylation Induced by the Arf Tumor Suppressor: A p53-Independent Function von Tago, Kenji, Chiocca, Susanna, Sherr, Charles J.

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N-terminal polyubiquitination and degradation of the Arf tumor suppressor von Kuo, Mei-Ling, den Besten, Willem, Bertwistle, David, Roussel, Martine F, Sherr, Charles J

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Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer von Ruscetti, Marcus, Morris, John P., Mezzadra, Riccardo, Russell, James, Leibold, Josef, Romesser, Paul B., Simon, Janelle, Kulick, Amanda, Ho, Yu-jui, Fennell, Myles, Li, Jinyang, Norgard, Robert J., Wilkinson, John E., Alonso-Curbelo, Direna, Sridharan, Ramya, Heller, Daniel A., de Stanchina, Elisa, Stanger, Ben Z., Sherr, Charles J., Lowe, Scott W.

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