Decline in Transcriptional Activity of Nrf2 Causes Age-Related Loss of Glutathione Synthesis, Which Is Reversible with Lipoic Acid von Suh, Jung H., Shenvi, Swapna V., Dixon, Brian M., Liu, Honglei, Jaiswal, Anil K., Liu, Rui-Ming, Hagen, Tory M., Ames, Bruce N.

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A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations von Zyba, Sarah J, Shenvi, Swapna V, Killilea, David W, Holland, Tai C, Kim, Elijah, Moy, Adrian, Sutherland, Barbara, Gildengorin, Virginia, Shigenaga, Mark K, King, Janet C

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Identification of age‐specific Nrf2 binding to a novel antioxidant response element locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity... von Shenvi, Swapna V., Smith, Eric, Hagen, Tory M.

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Glutathione Metabolism during Aging and in Alzheimer Disease von LIU, HONGLEI, WANG, HONG, SHENVI, SWAPNA, HAGEN, TORY M., LIU, RUI-MING

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Acute changes in cellular zinc alters zinc uptake rates prior to zinc transporter gene expression in Jurkat cells von Holland, Tai C., Killilea, David W., Shenvi, Swapna V., King, Janet C.

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Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD) von Suh, Jung H, Kanathezhath, Bindu, Shenvi, Swapna, Guo, Hua, Zhou, Alicia, Tiwana, Anureet, Kuypers, Frans, Ames, Bruce N, Walters, Mark C

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A nutrient‐dense, high‐fiber, fruit‐based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2‐wk trial von Mietus‐Snyder, Michele L., Shigenaga, Mark K., Suh, Jung H., Shenvi, Swapna V., Lal, Ashutosh, McHugh, Tara, Olson, Don, Lilienstein, Joshua, Krauss, Ronald M., Gildengoren, Ginny, McCann, Joyce C., Ames, Bruce N.

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A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements von McCann, Joyce C., Shigenaga, Mark K., Mietus‐Snyder, Michele L., Lal, Ashutosh, Suh, Jung H., Krauss, Ronald M., Gildengorin, Ginny L., Goldrich, Alisa M., Block, Devan S., Shenvi, Swapna V., McHugh, Tara H., Olson, Don A., Ames, Bruce N.

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Transcriptional regulation of rat γ-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element von Shenvi, Swapna V., Smith, Eric J., Hagen, Tory M.

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The Effect of Zinc Biofortified Wheat Produced via Foliar Application on Zinc Status: A Randomized, Controlled Trial in Indian Children von Signorell, Coralie, Kurpad, Anura V., Pauline, Maria, Shenvi, Swapna, Mukhopadhyay, Arpita, King, Janet C., Zimmermann, Michael B., Moretti, Diego

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Favorable safety profile of TERN-201, a highly selective inhibitor of vascular adhesion protein-1, in the non-alcoholic steatohepatitis phase 1b AVIATION study von Noureddin, Mazen, Lawitz, Eric, Alkhouri, Naim, Jenders, Robert, Denham, Douglas, Bhandari, Bal Raj, Jones, Christopher, Nelson, Cara H., Marmon, Tonya, Shenvi, Swapna, Graham, Hiba, Crittenden, Daria, Quirk, Erin, Chung, Diana

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Effect of Marginal Zinc Intake and Repletion on Essential Fatty Acid Metabolism von Suh, Jung, Burke, Sarah, Shigenaga, Mark, Killilea, David, Holland, Tai, Shenvi, Swapna, Sutherland, Barbara, King, Janet

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A Rat Primary Hepatocyte Culture Model for Aging Studies von Shenvi, Swapna V., Dixon, Brian M., Petersen Shay, Kate, Hagen, Tory M.

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High‐Density Lipoprotein Cholesterol Concentrations and Particle Size Are Modified by Dietary Zinc in Men von Shenvi, Swapna, Chen, Kevin, Kim, Elijah, Zyba, Sarah, King, Sarah, Shigenaga, Mark, Killilea, David, Holland, Tai, Sutherland, Barbara, Krauss, Ronald, King, Janet

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A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations1–3 von Zyba, Sarah J, Shenvi, Swapna V, Killilea, David W, Holland, Tai C, Kim, Elijah, Moy, Adrian, Sutherland, Barbara, Gildengorin, Virginia, Shigenaga, Mark K, King, Janet C

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A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations123 von Zyba, Sarah J, Shenvi, Swapna V, Killilea, David W, Holland, Tai C, Kim, Elijah, Moy, Adrian, Sutherland, Barbara, Gildengorin, Virginia, Shigenaga, Mark K, King, Janet C

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Short‐term low zinc intake alters DNA damage and zinc transporter expression without changing plasma zinc (122.2) von Burke, Sarah, Shenvi, Swapna, Killilea, David, Holland, Tai, Sutherland, Barbara, Kim, Elijah, Shigenaga, Mark, King, Janet

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Identification of age-specific Nrf2 binding to a novel ARE locus in the Gclc promoter: a compensatory means for the loss of glutathione synthetic capacity in the aging rat liver? von Shenvi, Swapna V., Smith, Eric, Hagen, Tory M.

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Host Nrf2 –glutathione Redox Dysregulation Precedes TNF-α Elevation and Predicts Severity of Graft Versus Host Disease in Experimental Transplantation von Suh, Jung H, Kanathezhath, Bindu, Swapna, Shenvi, Guo, Hua, Walters, Mark C., Ames, Bruce N.

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Abstract P279: A High Fiber Nutrient Dense Supplement Moves the Metabolome in Obese Parent[[Unable to Display Character: −]]Teen Dyads von Suh, Jung H, Narayanan, Nisha, Laine-Graves, Kirsten, McCann, Joyce C, Shenvi, Swapna V, Shigenaga, Mark K, Ames, Bruce N, Mietus-Snyder, Michele

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