A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors von Conroy, Jeffrey M., Pabla, Sarabjot, Glenn, Sean T., Seager, R. J., Van Roey, Erik, Gao, Shuang, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Mallon, Melissa, Lee, Yong Hee, DePietro, Paul, Nesline, Mary, Wang, Yirong, Lenzo, Felicia L., Klein, Roger, Zhang, Shengle

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Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer von Seager, R J, Senosain, Maria-Fernanda, Van Roey, Erik, Gao, Shuang, DePietro, Paul, Nesline, Mary K, Dash, Durga Prasad, Zhang, Shengle, Ko, Heidi, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian J, Severson, Eric A, Ramkissoon, Shakti, Conroy, Jeffrey M, Pabla, Sarabjot

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Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer von Wallen, Zachary D, Ko, Heidi, Nesline, Mary K, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Pabla, Sarabjot, Conroy, Jeffrey, Jackson, Jennifer B, Saini, Kamal S, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Sathyan, Pratheesh, Severson, Eric A, Ramkissoon, Shakti H

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Comparison of the Microsatellite Instability Analysis System and the Bethesda Panel for the Determination of Microsatellite Instability in Colorectal Cancers von Murphy, Kathleen M., Zhang, Shengle, Geiger, Tanya, Hafez, Michael J., Bacher, Jeff, Berg, Karin D., Eshleman, James R.

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The Spatio-Temporal Patterns of Macro Benthos Functional Groups and the Associated Factors Affecting Them After Wetland Restoration von Maoqiu, Wang, Yang, Hu, Ning, He, Mingxuan, Wu, Pengling, Wu, Qinyi, Wang, Bolun, Zhang, Shengle, Zhang, Meihua, Gao, Shubo, Fang

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The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer von Nesline, Mary K., Subbiah, Vivek, Previs, Rebecca A., Strickland, Kyle C., Ko, Heidi, DePietro, Paul, Biorn, Michael D., Cooper, Maureen, Wu, Nini, Conroy, Jeffrey, Pabla, Sarabjot, Zhang, Shengle, Wallen, Zachary D., Sathyan, Pratheesh, Saini, Kamal, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A., Ramkissoon, Shakti

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1499 Molecular and immune profiling of lobular-enriched versus non-lobular invasive breast cancers von Strickland, Kyle C, Pabla, Sarabjot, Ko, Heidi, Previs, Rebecca A, Wallen, Zachary D, Nesline, Mary K, Zhang, Shengle, Conroy, Jeffrey M, Jackson, Jennifer B, Saini, Kamal S, Jensen, Taylor J, Caveney, Brian, Eisenberg, Marcia, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

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Integration of tumor inflammation, cell proliferation, and traditional biomarkers improves prediction of immunotherapy resistance and response von Pabla, Sarabjot, Seager, R. J., Van Roey, Erik, Gao, Shuang, Hoefer, Carrie, Nesline, Mary K., DePietro, Paul, Burgher, Blake, Andreas, Jonathan, Giamo, Vincent, Wang, Yirong, Lenzo, Felicia L., Schoenborn, Margot, Zhang, Shengle, Klein, Roger, Glenn, Sean T., Conroy, Jeffrey M.

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O09: Potential germline variants are frequently identified when performing comprehensive genomic profiling of solid tumors von Jensen, Taylor, Noeth, Dagny, Cronister, Amy, DePietro, Paul, Klein, Roger, Nesline, Mary, Pabla, Sarabjot, Chenn, Anjen, Zhang, Shengle, Klein, Jonathan, Howarth, Sarah, Severson, Eric, Ramkissoon, Shakti, Eisenberg, Marcia, Reddy, Prasanth, Conroy, Jeffrey

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80 Cancer testis antigen burden: A novel predictive biomarker for immunotherapy in solid tumors von Pabla, Sarabjot, Seager, RJ, Lee, Yong Hee, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, DePietro, Paul, Nesline, Mary, Glenn, Sean, Zhang, Shengle, Conroy, Jeffrey

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77 Prevalence of secondary immunotherapeutic targets in the absence of established immune biomarkers in solid tumors von DePietro, Paul, Nesline, Mary, Lee, Yong Hee, Seager, RJ, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, Glenn, Sean, Zhang, Shengle, Klein, Roger, Pabla, Sarabjot, Conroy, Jeffrey

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70 Novel immunotherapeutic targets in cancer of unknown primary (CUP) von Nesline, Mary, DePietro, Paul, Lee, Yong Hee, Bliss, Zachery, Seager, RJ, Roey, Erik Van, Gao, Shuang, Giamo, Vincent, Burgher, Blake, Glenn, Sean, Zhang, Shengle, Pabla, Sarabjot, Klein, Roger, Conroy, Jeffrey

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DDIT3 Gene Break-apart as a Molecular Marker for Diagnosis of Myxoid Liposarcoma—Assay Validation and Clinical Experience von Narendra, Sonia, Valente, Alfredo, Tull, Jamie, Zhang, Shengle

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513 Comprehensive genomic and immune profiling of ALK fusion-positive and negative lung adenocarcinomas von Strickland, Kyle C, Wallen, Zachary D, Pabla, Sarabjot, Ko, Heidi, Nesline, Mary K, Previs, Rebecca A, Zhang, Shengle, Conroy, Jeffrey M, Sathyan, Pratheesh, Saini, Kamal S, Jensen, Taylor J, Caveney, Brian, Eisenberg, Marcia, Reddy, Prasanth, Muskavitch, Marc AT, Culver, Ken, Severson, Eric A, Ramkissoon, Shakti

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184 Distinct immunotherapy immune response phenotypes in non-small cell lung cancer present with unique genomic alteration profiles von Wallen, Zachary D, Seager, RJ, Pabla, Sarabjot, Nesline, Mary K, Roey, Erik Van, Gao, Shuang, Senosain, Maria-Fernanda, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

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175 Metastatic triple negative breast cancer has distinct tumor immune landscape von Seager, Robert, Ko, Heidi, Pabla, Sarabjot, Senosain, Maria-Fernanda, Roey, Erik Van, Gao, Shuang, Strickland, Kyle C, Previs, Rebecca A, Nesline, Mary K, Hastings, Stephanie B, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A, Ramkissoon, Shakti, Gandhi, Shipra

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176 Immune microenvironment of primary versus metastatic melanoma of the brain von Senosain, Maria-Fernanda, Ko, Heidi, Pabla, Sarabjot, Seager, Robert, Roey, Erik Van, Gao, Shuang, Strickland, Kyle C, Previs, Rebecca A, Nesline, Mary K, Hastings, Stephanie B, Zhang, Shengle, Conroy, Jeffrey M, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian, Severson, Eric A, Ramkissoon, Shakti

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183 Comprehensive genomic and immune profiling (CGIP) reveals a distinct genomic and immune gene expression profile for younger patients with non-small cell lung cancer (NSCLC) von Wallen, Zachary D, Ko, Heidi, Nesline, Mary K, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Zhang, Shengle, Pabla, Sarabjot, Conroy, Jeffrey M, Jackson, Jennifer B, Saini, Kamal S, Jensen, Taylor J, Caveney, Brian, Sathyan, Pratheesh, Reddy, Prasanth, Severson, Eric A, Ramkissoon, Shakti

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Utility of Immunohistochemistry and ETV6 (12p13) Gene Rearrangement in Identifying Secretory Carcinoma of Salivary Gland among Previously Diagnosed Cases of Acinic Cell Carcinoma von Naous, Rana, Zhang, Shengle, Valente, Alfredo, Stemmer, Melissa, Khurana, Kamal K.

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64 Cancer testis antigen co-expression landscape in solid tumors von Seager, RJ, Roey, Erik Van, Gao, Shuang, Andreas, Jonathan, Giamo, Vincent, Burgher, Blake, Lenzo, Felicia, Nesline, Mary, DePietro, Paul, Wang, Yirong, Glenn, Sean, Zhang, Shengle, Conroy, Jeffrey, Pabla, Sarabjot

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