The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer von Graham, Douglas K., DeRyckere, Deborah, Davies, Kurtis D., Earp, H. Shelton

Volltext

Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response von Ubil, Eric, Caskey, Laura, Holtzhausen, Alisha, Hunter, Debra, Story, Charlotte, Earp, H Shelton

Volltext

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution von Stanford, Jamie C, Young, Christian, Hicks, Donna, Owens, Philip, Williams, Andrew, Vaught, David B, Morrison, Meghan M, Lim, Jiyeon, Williams, Michelle, Brantley-Sieders, Dana M, Balko, Justin M, Tonetti, Debra, Earp, 3rd, H Shelton, Cook, Rebecca S

Volltext

MERTK Promotes Resistance to Irreversible EGFR Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancers Expressing Wild-type EGFR Family Members von Yan, Dan, Parker, Rebecca E, Wang, Xiaodong, Frye, Stephen V, Earp, 3rd, H Shelton, DeRyckere, Deborah, Graham, Douglas K

Volltext

MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer von Yan, Dan, Huelse, Justus M, Kireev, Dmitri, Tan, Zikang, Chen, Luxiao, Goyal, Subir, Wang, Xiaodong, Frye, Stephen V, Behera, Madhusmita, Schneider, Frank, Ramalingam, Suresh S, Owonikoko, Taofeek, Earp, H Shelton, DeRyckere, Deborah, Graham, Douglas K

Volltext

Inhibition of Lapatinib-induced Kinome Reprogramming in ERBB2-positive Breast Cancer by Targeting BET Family Bromodomains von Stuhlmiller, Timothy J., Miller, Samantha M., Zawistowski, Jon S., Nakamura, Kazuhiro, Beltran, Adriana S., Duncan, James S., Angus, Steven P., Collins, Kyla A.L, Granger, Deborah A., Reuther, Rachel A., Graves, Lee M., Gomez, Shawn M., Kuan, Pei-Fen, Parker, Joel S., Chen, Xin, Sciaky, Noah, Carey, Lisa A., Earp, H. Shelton, Jin, Jian, Johnson, Gary L.

Volltext

Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking von Porrello, Alessandro, Leslie, Patrick L., Harrison, Emily B., Gorentla, Balachandra K., Kattula, Sravya, Ghosh, Subrata K., Azam, Salma H., Holtzhausen, Alisha, Chao, Yvonne L., Hayward, Michele C., Waugh, Trent A., Bae, Sanggyu, Godfrey, Virginia, Randell, Scott H., Oderup, Cecilia, Makowski, Liza, Weiss, Jared, Wilkerson, Matthew D., Hayes, D. Neil, Earp, H. Shelton, Baldwin, Albert S., Wolberg, Alisa S., Pecot, Chad V.

Volltext

Macrophages and Dendritic Cells Use Different Axl/Mertk/Tyro3 Receptors in Clearance of Apoptotic Cells von Seitz, Heather M, Camenisch, Todd D, Lemke, Greg, Earp, H. Shelton, Matsushima, Glenn K

Volltext

Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study von Troester, Melissa A, Sun, Xuezheng, Allott, Emma H, Geradts, Joseph, Cohen, Stephanie M, Tse, Chiu-Kit, Kirk, Erin L, Thorne, Leigh B, Mathews, Michelle, Li, Yan, Hu, Zhiyuan, Robinson, Whitney R, Hoadley, Katherine A, Olopade, Olufunmilayo I, Reeder-Hayes, Katherine E, Earp, H Shelton, Olshan, Andrew F, Carey, Lisa A, Perou, Charles M

Volltext

Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex von Zawistowski, Jon S, Bevill, Samantha M, Goulet, Daniel R, Stuhlmiller, Timothy J, Beltran, Adriana S, Olivares-Quintero, Jose F, Singh, Darshan, Sciaky, Noah, Parker, Joel S, Rashid, Naim U, Chen, Xin, Duncan, James S, Whittle, Martin C, Angus, Steven P, Velarde, Sara Hanna, Golitz, Brian T, He, Xiaping, Santos, Charlene, Darr, David B, Gallagher, Kristalyn, Graves, Lee M, Perou, Charles M, Carey, Lisa A, Earp, H Shelton, Johnson, Gary L

Volltext

MERTK Inhibition as a Targeted Novel Cancer Therapy von Tanim, K M, Holtzhausen, Alisha, Thapa, Aashis, Huelse, Justus M, Graham, Douglas K, Earp, H Shelton

Volltext

Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma von Yu, Le, Deng, Yu, Wang, Xiaodong, Santos, Charlene, Davis, Ian J., Earp, H. Shelton, Liu, Pengda

Volltext

Germline Analysis from Tumor-Germline Sequencing Dyads to Identify Clinically Actionable Secondary Findings von Seifert, Bryce A, O'Daniel, Julianne M, Amin, Krunal, Marchuk, Daniel S, Patel, Nirali M, Parker, Joel S, Hoyle, Alan P, Mose, Lisle E, Marron, Andrew, Hayward, Michele C, Bizon, Christopher, Wilhelmsen, Kirk C, Evans, James P, Earp, 3rd, H Shelton, Sharpless, Norman E, Hayes, D Neil, Berg, Jonathan S

Volltext

Targeting MERTK and AXL in EGFR Mutant Non-Small Cell Lung Cancer von Yan, Dan, Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K.

Volltext

MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression von Jiang, Yao, Zhang, Yanqiong, Leung, Janet Y., Fan, Cheng, Popov, Konstantin I., Su, Siyuan, Qian, Jiayi, Wang, Xiaodong, Holtzhausen, Alisha, Ubil, Eric, Xiang, Yang, Davis, Ian, Dokholyan, Nikolay V., Wu, Gang, Perou, Charles M., Kim, William Y., Earp, H. Shelton, Liu, Pengda

Volltext

Molecular Pathways: MERTK Signaling in Cancer von CUMMINGS, Christopher T, DERYCKERE, Deborah, EARP, H. Shelton, GRAHAM, Douglas K

Volltext

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer von Cai, Ling, Tsai, Yi-Hsuan, Wang, Ping, Wang, Jun, Li, Dongxu, Fan, Huitao, Zhao, Yilin, Bareja, Rohan, Lu, Rui, Wilson, Elizabeth M., Sboner, Andrea, Whang, Young E., Zheng, Deyou, Parker, Joel S., Earp, H. Shelton, Wang, Gang Greg

Volltext

UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models von DeRyckere, Deborah, Lee-Sherick, Alisa B, Huey, Madeline G, Hill, Amanda A, Tyner, Jeffrey W, Jacobsen, Kristen M, Page, Lauren S, Kirkpatrick, Gregory G, Eryildiz, Fatma, Montgomery, Stephanie A, Zhang, Weihe, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, Graham, Douglas K

Volltext

Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma von Sinik, Lenka, Minson, Katherine A, Tentler, John J, Carrico, Jacqueline, Bagby, Stacey M, Robinson, William A, Kami, Rotem, Burstyn-Cohen, Tal, Eckhardt, S Gail, Wang, Xiaodong, Frye, Stephen V, Earp, H Shelton, DeRyckere, Deborah, Graham, Douglas K

Volltext

Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays von Coombs, Catherine C, Gillis, Nancy K, Tan, Xianming, Berg, Jonathan S, Ball, Markus, Balasis, Maria E, Montgomery, Nathan D, Bolton, Kelly L, Parker, Joel S, Mesa, Tania E, Yoder, Sean J, Hayward, Michele C, Patel, Nirali M, Richards, Kristy L, Walko, Christine M, Knepper, Todd C, Soper, John T, Weiss, Jared, Grilley-Olson, Juneko E, Kim, William Y, Earp, 3rd, H Shelton, Levine, Ross L, Papaemmanuil, Elli, Zehir, Ahmet, Hayes, D Neil, Padron, Eric

Volltext