Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-( N, N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious fa... von Zhang, Penglie, Huang, Wenrong, Wang, Lingyan, Bao, Liang, Jia, Zhaozhong J., Bauer, Shawn M., Goldman, Erick A., Probst, Gary D., Song, Yonghong, Su, Ting, Fan, Jingmei, Wu, Yanhong, Li, Wenhao, Woolfrey, John, Sinha, Uma, Wong, Paul W., Edwards, Susan T., Arfsten, Ann E., Clizbe, Lane A., Kanter, James, Pandey, Anjali, Park, Gary, Hutchaleelaha, Athiwat, Lambing, Joseph L., Hollenbach, Stanley J., Scarborough, Robert M., Zhu, Bing-Yan

Volltext

Total Synthesis of Motuporin (Nodularin-V) von Bauer, Shawn M, Armstrong, Robert W

Volltext

ADP receptor antagonists as antiplatelet therapeutics von Bauer, Shawn M

Volltext

N, N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors von JIA, Zhaozhong J, TING SU, WENRONG HUANG, WOOLFREY, John, SINHA, Uma, ARFSTEN, Ann E, HUTCHALEELAHA, Athiwat, HOLLENBACH, Stanley J, LAMBING, Joseph L, SCARBOROUGH, Robert M, ZHU, Bing-Yan, ZUCKETT, Jingmei F, YANHONG WU, GOLDMAN, Erick A, WENHAO LI, PENGLIE ZHANG, CLIZBE, Lane A, YONGHONG SONG, BAUER, Shawn M

Volltext

Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) von Ye, Bin, Bauer, Shawn, Buckman, Brad O., Ghannam, Ameen, Griedel, Brian D., Khim, Seock-Kyu, Lee, Wheeseong, Sacchi, Karna L., Shaw, Kenneth J., Liang, Amy, Wu, Qingyu, Zhao, Zuchun

Volltext

Parallel synthesis and structure–activity relationships of a series of highly potent, selective, and neutral factor Xa inhibitors von Bauer, Shawn M, Goldman, Erick A, Huang, Wenrong, Su, Ting, Wang, Lingyan, Woolfrey, John, Wu, Yanhong, Zuckett, Jingmei F, Arfsten, Ann, Huang, Brian, Kothule, Jaya, Lin, Joyce, May, Bridget, Sinha, Uma, Wong, Paul W, Hutchaleelaha, Athiwat, Scarborough, Robert M, Zhu, Bing-Yan

Volltext

Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo von Guilford, William J, Bauman, John G, Skuballa, Werner, Bauer, Shawn, Wei, Guo Ping, Davey, David, Schaefer, Caralee, Mallari, Cornell, Terkelsen, Jennifer, Tseng, Jih-Lie, Shen, Jun, Subramanyam, Babu, Schottelius, Arndt J, Parkinson, John F

Volltext

Specific Inhibition of Syk Suppresses Leukocyte Immune Function and Alleviates Inflammation In Rodent Models of Rheumatoid Arthritis von Coffey, Greg, Francis, DeGuzman, Inagaki, Mayuko, Pak, Yvonne, Delaney, Suzanne, Betz, Andreas, Jia, Zhaozhong J, Xu, Qing, Bauer, Shawn, Song, Yonghong, Pandey, Anjali, Baker, Dale, Hollenbach, Stanley, Phillips, David R., Sinha, Uma

Volltext

Inhibition of Syk Activity Is Sufficient for Inhibitory Effect in Animal Models of Autoimmune Diseases von Hollenbach, Stanley J, Coffey, Greg, DeGuzman, Francis R, Inagaki, Mayuko, Pandey, Anjali, Jia, Zhaozhong J, Xu, Qing, Bauer, Shawn, Baker, Dale, Nanda, Nisha, Phillips, David R, Sinha, Uma

Volltext

Specific Inhibition of Syk Is Sufficient to Disrupt Proliferation and Survival of Non-Hodgkin's Lymphoma Cell Lines without Concomitant Inhibition of JAK von Coffey, Greg, Luan, Peng, Delaney, Suzanne, Pandey, Anjali, Jia, Zhaozhong, Xu, Qing, Bauer, Shawn, Song, Yonghong, Conley, Pamela B., Phillips, David, Sinha, Uma

Volltext

Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido )-5-metho xybenzamide, a highly potent, selective, and orally efficacious fa... von Zhang, Penglie, Huang, Wenrong, Wang, Lingyan, Bao, Liang, Jia, Zhaozhong J, Bauer, Shawn M, Goldman, Erick A, Probst, Gary D, Song, Yonghong, Su, Ting, Fan, Jingmei, Wu, Yanhong, Li, Wenhao, Woolfrey, John, Sinha, Uma, Wong, Paul W, Edwards, Susan T, Arfsten, Ann E, Clizbe, Lane A, Kanter, James, Pandey, Anjali, Park, Gary, Hutchaleelaha, Athiwat, Lambing, Joseph L, Hollenbach, Stanley J, Scarborough, Robert M, Zhu, Bing-Yan

Volltext

Inhibitors of protein kinases von Bauer Shawn M, Pandey Anjali

Volltext bestellen

Construction of combinatorial chemical libraries using a rapid and efficient solid phase synthesis based on a multicomponent condensation reaction von Kim, Sang Woong, Bauer, Shawn M., Armstrong, Robert W.

Volltext

Novel 3-Oxa Lipoxin A 4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo von Guilford, William J., Bauman, John G., Skuballa, Werner, Bauer, Shawn, Wei, Guo Ping, Davey, David, Schaefer, Caralee, Mallari, Cornell, Terkelsen, Jennifer, Tseng, Jih-Lie, Shen, Jun, Subramanyam, Babu, Schottelius, Arndt J., Parkinson, John F.

Volltext

Multicomponent solution phase synthesis of dehydroamino acid derivatives based on the Passerini reaction von Kim, Sang Woong, Bauer, Shawn M., Armstrong, Robert W.

Volltext

Inhibitors of protein kinases von Jia, Zhaozhong J, Huang, Wolin, Venkataramani, Chandrasekar, Bauer, Shawn M, Pandey, Anjali, Xu, Qing, Rose, Jack W, Mehrotra, Mukund, Song, Yonghong

Volltext bestellen

PYRAZINE KINASE INHIBITORS von XU, QING, PANDEY, ANJALI, SONG, YONGHONG, JIA, ZHAOZHONG J, BAUER, SHAWN M, KANE, BRIAN

Volltext bestellen

Inhibitors of protein kinases von PANDEY ANJALI, BAUER SHAWN M

Volltext bestellen

1,2,4-TRIAZINE-6-CARBOXAMIDE KINASE INHIBITORS von XU, QING, PANDEY, ANJALI, SONG, YONGHONG, JIA, ZHAOZHONG J, ROSE, JACK, BAUER, SHAWN M, KANE, BRIAN

Volltext bestellen

NICOTINAMIDES AS SYK MODULATORS von XU, QING, PANDEY, ANJALI, SONG, YONGHONG, JIA, ZHAOZHONG J, BAUER, SHAWN M, KANE, BRIAN

Volltext bestellen