Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension von Shaw, Duncan E., Smith, Nichola, Beerli, Rene, Cotesta, Simona, D’Alessandro, Pier-Luca, Edwards, Anne-Marie, Lattmann, Rene, Lizos, Dimitrios, Pulz, Robert, Rooney, Lisa, Sohal, Bindi, Rynn, Caroline, Taylor, Jessica, Troxler, Thomas, Williams, Gareth, Guth, Sabine, Rowlands, David

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Interactions between β2-Adrenoceptor Ligands and Membrane: Atomic-Level Insights from Magic-Angle Spinning NMR von Yan, Si, Shaw, Duncan E, Yang, Linhong, Sandham, David A, Healy, Mark P, Reilly, John, Wang, Bing

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Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension von Shaw, Duncan E, Baig, Ferheen, Bruce, Ian, Chamoin, Sylvie, Collingwood, Stephen P, Cross, Sarah, Dayal, Satish, Drückes, Peter, Furet, Pascal, Furminger, Vikki, Haggart, Deborah, Hussey, Martin, Konstantinova, Irena, Loren, Jon C, Molteni, Valentina, Roberts, Sonia, Reilly, John, Saunders, Alex M, Stringer, Rowan, Sviridenko, Lilya, Thomas, Matthew, Thomson, Christopher G, Tomlins, Christine, Wen, Ben, Yeh, Vince, Pearce, Andrew C

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4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors von Churcher, Ian, Beher, Dirk, Best, Jonathan D., Castro, José L., Clarke, Earl E., Gentry, Amy, Harrison, Timothy, Hitzel, Laure, Kay, Euan, Kerrad, Sonia, Lewis, Huw D., Morentin-Gutierrez, Pablo, Mortishire-Smith, Russell, Oakley, Paul J., Reilly, Michael, Shaw, Duncan E., Shearman, Mark S., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D.J.

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2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution von COOPER, Laura C, CHICCHI, Gary G, WATT, Alan P, WILLIAMS, Angela R, SWAIN, Christopher J, DINNELL, Kevin, ELLIOTT, Jason M, HOLLINGWORTH, Gregory J, KURTZ, Mare M, LOCKER, Karen L, MORRISON, Denise, SHAW, Duncan E, TSAO, Kwei-Lan

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Two Contrasting Asymmetric Approaches to Muscarine Based on 5-endo-trig Cyclisations von Knight, David W., Shaw, Duncan E., Staples, Emily R.

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4,4-Disubstituted cyclohexylamine NK1 receptor antagonists I von ELLIOTT, Jason M, CASTRO, Jose L, SWAIN, Christopher J, TSAO, Kwei-Lan, LIHU YANG, CHICCHI, Gary G, COOPER, Laura C, DINNELL, Kevin, HOLLINGWORTH, Gregory J, RIDGILL, Mark P, RYCROFT, Wayne, KURTZ, Marc M, SHAW, Duncan E

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On the stereoselection of iodolactonizations of 3-silyloxyalk-5-enoic acids von Bedford, Simon B., Fenton, Garry, Knight, David W., Shaw, Duncan E.

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A radical cyclisation approach to the 2-oxabicyclo[2.2.1]heptane ring system von Shaw, Duncan E., Fenton, Garry, Knight, David W.

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4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I von Elliott, Jason M, Castro, Jose L, Chicchi, Gary G, Cooper, Laura C, Dinnell, Kevin, Hollingworth, Gregory J, Ridgill, Mark P, Rycroft, Wayne, Kurtz, Marc M, Shaw, Duncan E, Swain, Christopher J, Tsao, Kwei-Lan, Yang, Lihu

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4,4-Disubstituted cyclohexylamine NK 1 receptor antagonists I von Elliott, Jason M, Castro, Jose L, Chicchi, Gary G, Cooper, Laura C, Dinnell, Kevin, Hollingworth, Gregory J, Ridgill, Mark P, Rycroft, Wayne, Kurtz, Marc M, Shaw, Duncan E, Swain, Christopher J, Tsao, Kwei-Lan, Yang, Lihu

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Model studies of the overall 5-endo-trig iodocyclization of homoallylic alcohols von Bedford, Simon B., Bell, Kathryn E., Bennett, Frank, Hayes, Christopher J., Knight, David W., Shaw, Duncan E.

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2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution von Cooper, Laura C., Chicchi, Gary G., Dinnell, Kevin, Elliott, Jason M., Hollingworth, Gregory J., Kurtz, Marc M., Locker, Karen L., Morrison, Denise, Shaw, Duncan E., Tsao, Kwei-Lan, Watt, Alan P., Williams, Angela R., Swain, Christopher J.

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Cyclic sulfonamides for inhibition of gamma-secretase von NADIN ALAN J, SHAW DUNCAN E, WILLIAMS BRIAN J, DINNELL KEVIN, OWENS ANDREW P, HARRISON TIMOTHY

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Novel cyclohexyl sulphones von CHURCHER IAN, NADIN ALAN J, SHAW DUNCAN E, WILLIAMS BRIAN J, WILLIAMS SUSANNAH, DINNELL KEVIN, KERRAD SONIA, HARRISON TIMOTHY, OAKLEY PAUL J, TEALL MARTIN R

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Tetrahydropyran derivatives and their use as therapeutic agents von ELLIOTT JASON M, SHAW DUNCAN E, WILLIAMS BRIAN J, DIRAT OLIVIER, KULAGOWSKI JANUSZ J, RAUBO PIOTR A, OWEN SIMON N

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Synthesis of cyclohexanone derivatives von SCOTT JEREMY P, SHAW DUNCAN E, BRANDS KAREL M.J, DAVIES ANTONY J, OAKLEY PAUL J, TEALL MARTIN R

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Tetrahydropyran compounds as tachykinin antagonists von ELLIOTT JASON M, SHAW DUNCAN E, HUSCROFT IAN T, DIRAT OLIVIER, SWAIN CHRISTOPHER J, KULAGOWSKI JANUSZ J, STERNFELD FRANCINE, JELLEY RICHARD A, RAUBO PIOTR A

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ChemInform Abstract: Model Studies of the Overall 5-endo-trig Iodocyclization of Homoallylic Alcohols von Bedford, Simon B., Bell, Kathryn E., Bennett, Frank, Hayes, Christopher J., Knight, David W., Shaw, Duncan E.

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Novel cyclohexyl sulphones von CHURCHER IAN, NADIN ALAN J, SHAW DUNCAN E, WILLIAMS BRIAN J, WILLIAMS SUSANNAH, DINNELL KEVIN, KERRAD SONIA, HARRISON TIMOTHY, OAKLEY PAUL J, TEALL MARTIN R

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