HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2 von Hanker, Ariella B, Garrett, Joan T, Estrada, Mónica Valeria, Moore, Preston D, Ericsson, Paula González, Koch, James P, Langley, Emma, Singh, Sharat, Kim, Phillip S, Frampton, Garrett M, Sanford, Eric, Owens, Philip, Becker, Jennifer, Groseclose, M Reid, Castellino, Stephen, Joensuu, Heikki, Huober, Jens, Brase, Jan C, Majjaj, Samira, Brohée, Sylvain, Venet, David, Brown, David, Baselga, José, Piccart, Martine, Sotiriou, Christos, Arteaga, Carlos L

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The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease von Vande Casteele, Niels, Khanna, Reena, Levesque, Barrett G, Stitt, Larry, Zou, G Y, Singh, Sharat, Lockton, Steve, Hauenstein, Scott, Ohrmund, Linda, Greenberg, Gordon R, Rutgeerts, Paul J, Gils, Ann, Sandborn, William J, Vermeire, Séverine, Feagan, Brian G

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Early Trough Levels and Antibodies to Infliximab Predict Safety and Success of Reinitiation of Infliximab Therapy von Baert, Filip, Drobne, David, Gils, Ann, Vande Casteele, Niels, Hauenstein, Scott, Singh, Sharat, Lockton, Steve, Rutgeerts, Paul, Vermeire, Séverine

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Development and validation of a homogeneous mobility shift assay for the measurement of infliximab and antibodies-to-infliximab levels in patient serum von Wang, Shui-Long, Ohrmund, Linda, Hauenstein, Scott, Salbato, Jared, Reddy, Rukmini, Monk, Patrick, Lockton, Steven, Ling, Nicholas, Singh, Sharat

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Combined serological, genetic, and inflammatory markers differentiate non-IBD, Crohn's disease, and ulcerative colitis patients von Plevy, Scott, Silverberg, Mark S, Lockton, Steve, Stockfisch, Tom, Croner, Lisa, Stachelski, Jordan, Brown, Michelle, Triggs, Cheryl, Chuang, Emil, Princen, Fred, Singh, Sharat

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A novel class of polymeric fluorescent dyes assembled using a DNA synthesizer von Matray, Tracy, Singh, Sharat, Sherif, Hesham, Farber, Kenneth, Kwang, Erin, VanBrunt, Michael, Matsui, Eriko, Yada, Hiroaki

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Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer von Tao, Jessica J, Castel, Pau, Radosevic-Robin, Nina, Elkabets, Moshe, Auricchio, Neil, Aceto, Nicola, Weitsman, Gregory, Barber, Paul, Vojnovic, Borivoj, Ellis, Haley, Morse, Natasha, Viola-Villegas, Nerissa Therese, Bosch, Ana, Juric, Dejan, Hazra, Saswati, Singh, Sharat, Kim, Phillip, Bergamaschi, Anna, Maheswaran, Shyamala, Ng, Tony, Penault-Llorca, Frédérique, Lewis, Jason S, Carey, Lisa A, Perou, Charles M, Baselga, José, Scaltriti, Maurizio

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An In vivo Platform for Translational Drug Development in Pancreatic Cancer von Rubio-Viqueira, Belen, Jimeno, Antonio, Cusatis, George, Zhang, Xianfeng, Iacobuzio-Donahue, Christine, Karikari, Collins, Shi, Chanjusn, Danenberg, Kathleen, Danenberg, Peter V, Kuramochi, Hidekazu, Tanaka, Koji, Singh, Sharat, Salimi-Moosavi, Hossein, Bouraoud, Nadia, Amador, Maria L, Altiok, Soner, Kulesza, Piotr, Yeo, Charles, Messersmith, Wells, Eshleman, James, Hruban, Ralph H, Maitra, Anirban, Hidalgo, Manuel

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Monitoring of adalimumab and antibodies-to-adalimumab levels in patient serum by the homogeneous mobility shift assay von Wang, Shui-Long, Hauenstein, Scott, Ohrmund, Linda, Shringarpure, Reshma, Salbato, Jared, Reddy, Rukmini, McCowen, Kevin, Shah, Shawn, Lockton, Steven, Chuang, Emil, Singh, Sharat

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A Matrix-based Model Predicts Primary Response to Infliximab in Crohn’s Disease von Billiet, Thomas, Papamichael, Konstantinos, de Bruyn, Magali, Verstockt, Bram, Cleynen, Isabelle, Princen, Fred, Singh, Sharat, Ferrante, Marc, Van Assche, Gert, Vermeire, Severine

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Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independent of KRAS mutational status von Lee, Jeeyun, Jain, Anjali, Kim, Phillip, Lee, Tani, Kuller, Anne, Princen, Fred, In-GuDo, Kim, Suk Hyeong, Park, Joon Oh, Park, Young Suk, Singh, Sharat, Kim, Hee Cheol

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A novel proteomics-based clinical diagnostics technology identifies heterogeneity in activated signaling pathways in gastric cancers von Lee, Jeeyun, Kim, Sung, Kim, Phillip, Liu, Xinjun, Lee, Tani, Kim, Kyoung-Mee, Do, In-Gu, Park, Joon Oh, Park, Se Hoon, Jang, Jiryeon, Hoe, Nicholas, Harvie, Gulia, Kuller, Anne, Jain, Anjali, Meyer, Gary, Leesman, Glen, Park, Young Suk, Choi, Min Gew, Sohn, Tae Sung, Bae, Jae Moon, Lim, Ho Yeong, Singh, Sharat, Kang, Won Ki

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Tu1148 Mechanisms of Loss of Response to Adalimumab in Crohn's Disease von Wolf, Douglas C, Hauenstein, Scott, Lockton, Steven, Singh, Sharat

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Postpartum Amenorrhoea among Manipuri Women: A Survival Analysis von Singh, N. Sanajaoba, Singh, N. Sharat, Narendra, R.K.

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Stratified Medicine: Maximizing Clinical Benefit by Biomarker-Driven Health Care von Singh, Sharat

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Fr488 TARGETED DELIVERY OF SOLUBLE TOFACITINIB CITRATE TO THE SITE OF INFLAMMATION TO IMPROVE EFFICACY AND SAFETY von Lee, Shaoying N., Stork, Cheryl A., Singh, Sharat, Chuang, Emil

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Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients von Kim, Phillip, Liu, Xinjun, Lee, Tani, Liu, Limin, Barham, Robert, Kirkland, Richard, Leesman, Glen, Kuller, Anne, Ybarrondo, Belen, Ng, Shi-Chung, Singh, Sharat

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Determinants of duration of breastfeeding amongst women in Manipur von Singh, N Sanajaoba, Singh, N Sharat

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DEVELOPMENT OF A NOVEL DRUG DELIVERY SYSTEM (DDS) TO DELIVER DRUGS DIRECTLY TO THE COLONIC MUCOSA TO IMPROVE EFFICACY AND REDUCE SYSTEMIC EXPOSURE FOR THE TREATMENT OF ULCERATIVE C... von Lee, Shaoying Nikki, Stork, Cheryl, Razag, Ghesal, Quintana, Nelson, Wahl, Chris, Singh, Sharat

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POTENTIAL EFFECTS OF FOOD ON A NOVEL DRUG DELIVERY SYSTEM (DDS) TO DELIVER A THERAPEUTIC COMPOUND IN THE COLON von Lee, Shaoying Nikki, Stork, Cheryl, Razag, Ghesal, Quintana, Nelson, Wahl, Chris, Singh, Sharat

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