Discovery of Potent and Selective RSK Inhibitors as Biological Probes von Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Lindvall, Mika, Appleton, Brent A., Shafer, Cynthia M.

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Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma von Williams, Teresa E, Subramanian, Sharadha, Verhagen, Joelle, McBride, Christopher M, Costales, Abran, Sung, Leonard, Antonios-McCrea, William, McKenna, Maureen, Louie, Alicia K, Ramurthy, Savithri, Levine, Barry, Shafer, Cynthia M, Machajewski, Timothy, Renhowe, Paul A, Appleton, Brent A, Amiri, Payman, Chou, James, Stuart, Darrin, Aardalen, Kimberly, Poon, Daniel

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Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhi... von Ramurthy, Savithri, Taft, Benjamin R., Aversa, Robert J., Barsanti, Paul A., Burger, Matthew T., Lou, Yan, Nishiguchi, Gisele A., Rico, Alice, Setti, Lina, Smith, Aaron, Subramanian, Sharadha, Tamez, Victoriano, Tanner, Huw, Wan, Lifeng, Hu, Cheng, Appleton, Brent A., Mamo, Mulugeta, Tandeske, Laura, Tellew, John E., Huang, Shenlin, Yue, Qn, Cliaudliary, Apurva, Tian, Hung, Iyer, Raman, Hassan, A. Quamrul, Griner, Lesley A. Mathews, La Bonte, Laura R., Cooke, Vesselina G., Van Abbema, Anne, Merritt, Hanne, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Mishina, Yuji, Wang, Yingyun, Haling, Jacob R., Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Sellers, William R., Lees, Emma, Shao, Wenlin, Dillon, Michael P., Stuart, Darrin D.

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Design and Discovery of N‑(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inh... von Ramurthy, Savithri, Taft, Benjamin R, Aversa, Robert J, Barsanti, Paul A, Burger, Matthew T, Lou, Yan, Nishiguchi, Gisele A, Rico, Alice, Setti, Lina, Smith, Aaron, Subramanian, Sharadha, Tamez, Victoriano, Tanner, Huw, Wan, Lifeng, Hu, Cheng, Appleton, Brent A, Mamo, Mulugeta, Tandeske, Laura, Tellew, John E, Huang, Shenlin, Yue, Qin, Chaudhary, Apurva, Tian, Hung, Iyer, Raman, Hassan, A. Quamrul, Mathews Griner, Lesley A, La Bonte, Laura R, Cooke, Vesselina G, Van Abbema, Anne, Merritt, Hanne, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Mishina, Yuji, Wang, Yingyun, Haling, Jacob R, Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Sellers, William R, Lees, Emma, Shao, Wenlin, Dillon, Michael P, Stuart, Darrin D

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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors von Ramurthy, Savithri, Pfister, Keith B., Boyce, Rustum S., Brown, Sean P., Costales, Abran Q., Desai, Manoj C., Fang, Eric, Levine, Barry H., Ng, Simon C., Nuss, John M., Ring, David B., Shafer, Cynthia M., Shu, Wei, Subramanian, Sharadha, Wagman, Allan S., Wang, Haixia, Bussiere, Dirksen E.

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Design and synthesis of potent RSK inhibitors von Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Appleton, Brent A., Lindvall, Mika, Shafer, Cynthia M.

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Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors von Ramurthy, Savithri, Costales, Abran, Jansen, Johanna M., Levine, Barry, Renhowe, Paul A., Shafer, Cynthia M., Subramanian, Sharadha

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Structure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors von Barsanti, Paul A, Pan, Yue, Lu, Yipin, Jain, Rama, Cox, Matthew, Aversa, Robert J, Dillon, Michael P, Elling, Robert, Hu, Cheng, Jin, Xianming, Knapp, Mark, Lan, Jiong, Ramurthy, Savithri, Rudewicz, Patrick, Setti, Lina, Subramanian, Sharadha, Mathur, Michelle, Taricani, Lorena, Thomas, George, Xiao, Linda, Yue, Qin

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Abstract B38: Inhibiting mutated KRAS, a broken switch of effector pathways von Jansen, Johanna, Jahnke, Wolfgang, Fong, Susan, Tandeske, Laura, Wartchow, Charles, Pfister, Keith, Zavorotinskaya, Tatiana, Blechschmidt, Anke, Bussiere, Dirksen, Dai, Yumin, Dove, Jeff, Fang, Eric, Farley, David, Florent, Jean-Michel, Fuller, John, Gokhin, Simona, Gossert, Alvar, Hekmat-Nejad, Mohammad, Henry, Chrystèle, Klopp, Julia, Lenahan, Bill, Lingel, Andreas, Meyer, Arndt, Narberes, Jamie, Pardee, Gwynn, Paris, C Gregory, Ramurthy, Savithri, Renhowe, Paul, Rieffel, Sebastien, Shoemaker, Kevin, Subramanian, Sharadha, Tsang, Tiffany, Widger, Stephania, Widmer, Armin, Zaror, Isabel, Hardy, Stephen

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Correction to Design and Synthesis of Orally Bioavailable Benzimidazole Reverse Amides as Pan RAF Kinase Inhibitors von Subramanian, Sharadha, Costales, Abran, Williams, Teresa E, Levine, Barry, McBride, Christopher M, Poon, Daniel, Amiri, Payman, Renhowe, Paul A, Shafer, Cynthia M, Stuart, Darrin, Verhagen, Joelle, Ramurthy, Savithri

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BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS von RAMURTHY, SAVITHRI, YUSUFF, NAEEM, SUBRAMANIAN, SHARADHA, NISHIGUCHI, GISELE, BURGER, MATTHEW, HU, CHENG, POLYAKOV, VALERY, RICO, ALICE, SETTI, LINA, SMITH, AARON, WAN, LIFENG, DIPESA, ALAN, PAN, YUE, AVERSA, ROBERT, LOU, YAN, BARSANTI, PAUL A, TAFT, BENJAMIN, TANNER, HUW, DILLON, MICHAEL PATRICK

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Compounds and compositions as kinase inhibitors von Subramanian, Sharadha, Barsanti, Paul Andrew, Nishiguchi, Gisele A, Lou, Yan, Taft, Benjamin R, Ramurthy, Savithri, Tanner, Huw Rowland, Wan, Lifeng, Polyakov, Valery Rostislavovich, Burger, Matthew T

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Substituted pyrrolo[3,4-d]pyrimidines as kinase inhibitors von Rauniyar Vivek, Dillon Michael Patrick, Lindvall Mika, Tanner Huw Rowland, Poon Daniel, Subramanian Sharadha, Ramurthy Savithri, Shafer Cynthia

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BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS von NISHIGUCHI, Gisele, PAN, Yue, RICO, Alice, SETTI, Lina, POLYAKOV, Valery, DIPESA, Alan, LOU, Yan, BARSANTI, Paul Andrew, HU, Cheng, SMITH, Aaron, BURGER, Matthew, WAN, Lifeng, TAFT, Benjamin, TANNER, Huw, AVERSA, Robert John, YUSUFF, Naeem, SUBRAMANIAN, Sharadha, DILLON, Michael Patrick, RAMURTHY, Savithri

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COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS von BURGER, Matthew T, TAFT, Benjamin R, SUBRAMANIAN, Sharadha, LOU, Yan, POLYAKOV, Valery Rostislavovich, BARSANTI, Paul Andrew, RAMURTHY, Savithri, NISHIGUCHI, Gisele A, TANNER, Huw Rowland, WAN, Lifeng

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BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS von PAN, Yue, DIPESA, Alan, LOU, Yan, POLYAKOV, Valery Rostislavovich, BARSANTI, Paul Andrew, HU, Cheng, RICO, Alice C, SMITH, Aaron, SETTI, Lina Quattrocchio, WAN, Lifeng, BURGER, Matthew T, TAFT, Benjamin R, AVERSA, Robert John, YUSUFF, Naeem, TANNER, Huw Roland, SUBRAMANIAN, Sharadha, DILLON, Michael Patrick, RAMURTHY, Savithri, NISHIGUCHI, Gisele A

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COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS von SENDZIK, Martin, LOU, Yan, RICO, Alice C, SETTI, Lina Quattrocchio, WAN, Lifeng, BURGER, Matthew T, TAFT, Benjamin R, AVERSA, Robert John, RAUNIYAR, Vivek, DINEEN JR., Thomas A, SUBRAMANIAN, Sharadha, DILLON, Michael Patrick, RAMURTHY, Savithri, NISHIGUCHI, Gisele A, TANNER, Huw Rowland

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Biaryl amide compounds as kinase inhibitors von Pan, Yue, Subramanian, Sharadha, Lou, Yan, Taft, Benjamin R, Yusuff, Naeem, Tanner, Huw Roland, Hu, Cheng, Aversa, Robert John, Barsanti, Paul Andrew, Rico, Alice C, Nishiguchi, Gisele A, Setti, Lina Quattrocchio, Smith, Aaron, Ramurthy, Savithri, Dipesa, Alan, Wan, Lifeng, Polyakov, Valery Rostislavovich, Burger, Matthew T, Dillon, Michael Patrick

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2,6-disubstituted quinazolines, quinoxalines, quinolines and isoquinolines and methods of their use as inhibitors of Raf kinase von Ramurthy, Savithri, Renhowe, Paul A, Subramanian, Sharadha

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BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS von Pan, Yue, Subramanian, Sharadha, Aversa, Robert, Lou, Yan, Yusuff, Naeem, Burger, Matthew, Taft, Benjamin, Barsanti, Paul A, Hu, Cheng, Polyakov, Valery, Smith, Aaron, Tanner, Huw, Ramurthy, Savithri, Dipesa, Alan, Nishiguchi, Gisele, Setti, Lina, Wan, Lifeng, Dillon, Michael Patrick, Rico, Alice

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