Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies von Peng, Sheng-Bin, Zhang, Xiaoyi, Paul, Donald, Kays, Lisa M, Ye, Ming, Vaillancourt, Peter, Dowless, Michele, Stancato, Louis F, Stewart, Julie, Uhlik, Mark T, Long, Haiyan, Chu, Shaoyou, Obungu, Victor H

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Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis von Qian, Yue-Wei, Schmidt, Robert J., Zhang, Youyan, Chu, Shaoyou, Lin, Aimin, Wang, He, Wang, Xiliang, Beyer, Thomas P., Bensch, William R., Li, Weiming, Ehsani, Mariam E., Lu, Deshun, Konrad, Robert J., Eacho, Patrick I., Moller, David E., Karathanasis, Sotirios K., Cao, Guoqing

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AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase von Chen, Yan Qun, Kuo, Ming-Shang, Li, Shuyu, Bui, Hai H., Peake, David A., Sanders, Philip E., Thibodeaux, Stefan J., Chu, Shaoyou, Qian, Yue-Wei, Zhao, Yang, Bredt, David S., Moller, David E., Konrad, Robert J., Beigneux, Anne P., Young, Stephen G., Cao, Guoqing

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Role of a cellular thermal shift assay on evaluation of drug‐target engagement for compound selection von Mason, Emily R, Chu, Shaoyou

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Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays von Lee, Jonathan A, Shinn, Paul, Jaken, Susan, Oliver, Sarah, Willard, Francis S, Heidler, Steven, Peery, Robert B, Oler, Jennifer, Chu, Shaoyou, Southall, Noel, Dexheimer, Thomas S, Smallwood, Jeffrey, Huang, Ruili, Guha, Rajarshi, Jadhav, Ajit, Cox, Karen, Austin, Christopher P, Simeonov, Anton, Sittampalam, G Sitta, Husain, Saba, Franklin, Natalie, Wild, David J, Yang, Jeremy J, Sutherland, Jeffrey J, Thomas, Craig J

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SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease von Jesudason, Cynthia D., Mason, Emily R., Chu, Shaoyou, Oblak, Adrian L., Javens‐Wolfe, June, Moussaif, Mustapha, Durst, Greg, Hipskind, Philip, Beck, Daniel E., Dong, Jiajun, Amarasinghe, Ovini, Zhang, Zhong‐Yin, Hamdani, Adam K., Singhal, Kratika, Mesecar, Andrew D., Souza, Sarah, Jacobson, Marlene, Salvo, Jerry Di, Soni, Disha M., Kandasamy, Murugesh, Masters, Andrea R., Quinney, Sara K, Doolen, Suzanne, Huhe, Hasi, Rizzo, Stacey J. Sukoff, Lamb, Bruce T., Palkowitz, Alan D., Richardson, Timothy I.

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Green Fluorescent Protein Variants as Ratiometric Dual Emission pH Sensors. 1. Structural Characterization and Preliminary Application von Hanson, George T, McAnaney, Tim B, Park, Eun Sun, Rendell, Marla E. P, Yarbrough, Daniel K, Chu, Shaoyou, Xi, Lixuan, Boxer, Steven G, Montrose, Marshall H, Remington, S. James

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Establishment and application of a microglial phagocytosis/cell health high content assay for Alzheimer’s disease drug discovery targeting microglia von Mason, Emily R, Soni, Disha, Chu, Shaoyou

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Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells von Sours, Sherry, Du, Juan, Chu, Shaoyou, Ding, Min, Zhou, Xin J, Ma, Rong

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AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery von Potjewyd, Frances M., Annor‐Gyamfi, Joel K., Aubé, Jeffrey, Chu, Shaoyou, Conlon, Ivie L., Frankowski, Kevin J., Guduru, Shiva K. R., Hardy, Brian P., Hopkins, Megan D., Kinoshita, Chizuru, Kireev, Dmitri B., Mason, Emily R., Moerk, Charles T., Nwogbo, Felix, Pearce, Kenneth H., Richardson, Timothy I., Rogers, David A., Soni, Disha M., Stashko, Michael, Wang, Xiaodong, Wells, Carrow, Willson, Timothy M., Frye, Stephen V., Young, Jessica E., Axtman, Alison D.

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Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology von Potjewyd, Frances M., Annor‐Gyamfi, Joel K., Aubé, Jeffrey, Chu, Shaoyou, Conlon, Ivie L., Frankowski, Kevin J., Guduru, Shiva K. R., Hardy, Brian P., Hopkins, Megan D., Kinoshita, Chizuru, Kireev, Dmitri B., Mason, Emily R., Moerk, Charles T., Nwogbo, Felix, Pearce, Kenneth H., Richardson, Timothy I., Rogers, David A., Soni, Disha M., Stashko, Michael, Wang, Xiaodong, Wells, Carrow, Willson, Timothy M., Frye, Stephen V., Young, Jessica E., Axtman, Alison D.

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Dynamic Assessment of Mitoxantrone Resistance and Modulation of Multidrug Resistance by Valspodar (PSC833) in Multidrug Resistance Human Cancer Cells von Shen, Fei, Bailey, Barbara J, Chu, Shaoyou, Bence, Aimee K, Xue, Xinjian, Erickson, Priscilla, Safa, Ahmad R, Beck, William T, Erickson, Leonard C

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The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration von Sarmah, Swapnalee, Curtis, Courtney, Mahin, Jennifer, Farrell, Mark, Engler, Thomas A, Sanchez-Felix, Manuel V, Sato, Masahiko, Ma, Yanfai Linda, Chu, Shaoyou, Marrs, James A

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Multiparametric Cell-Based Assay for the Evaluation of Transcription Inhibition by High-Content Imaging von Torres-Guzmán, Raquel, Chu, Shaoyou, Velasco, Juan A., Lallena, María José

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High concentration of glucose inhibits glomerular endothelial eNOS through a PKC mechanism von Chu, Shaoyou, Bohlen, H Glenn

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Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction von Lyall, Vijay, Alam, Rammy I, Phan, Duy Q, Ereso, Glenn L, Phan, Tam-Hao T, Malik, Shahbaz A, Montrose, Marshall H, Chu, Shaoyou, Heck, Gerard L, Feldman, George M, DeSimone, John A

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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib von Gong, Xueqian, Litchfield, Lacey M., Webster, Yue, Chio, Li-Chun, Wong, Swee Seong, Stewart, Trent R., Dowless, Michele, Dempsey, Jack, Zeng, Yi, Torres, Raquel, Boehnke, Karsten, Mur, Cecilia, Marugán, Carlos, Baquero, Carmen, Yu, Chunping, Bray, Steven M., Wulur, Isabella H., Bi, Chen, Chu, Shaoyou, Qian, Hui-Rong, Iversen, Philip W., Merzoug, Farhana F., Ye, Xiang S., Reinhard, Christoph, De Dios, Alfonso, Du, Jian, Caldwell, Charles W., Lallena, María José, Beckmann, Richard P., Buchanan, Sean G.

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Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene von Gong, Xueqian, Du, Jian, Parsons, Stephen H, Merzoug, Farhana F, Webster, Yue, Iversen, Philip W, Chio, Li-Chun, Van Horn, Robert D, Lin, Xi, Blosser, Wayne, Han, Bomie, Jin, Shaoling, Yao, Sufang, Bian, Huimin, Ficklin, Chris, Fan, Li, Kapoor, Avnish, Antonysamy, Stephen, Mc Nulty, Ann M, Froning, Karen, Manglicmot, Danalyn, Pustilnik, Anna, Weichert, Kenneth, Wasserman, Stephen R, Dowless, Michele, Marugán, Carlos, Baquero, Carmen, Lallena, María José, Eastman, Scott W, Hui, Yu-Hua, Dieter, Matthew Z, Doman, Thompson, Chu, Shaoyou, Qian, Hui-Rong, Ye, Xiang S, Barda, David A, Plowman, Gregory D, Reinhard, Christoph, Campbell, Robert M, Henry, James R, Buchanan, Sean G

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Cdk1 Activity Is Required for Mitotic Activation of Aurora A during G2/M Transition of Human Cells von Van Horn, Robert D., Chu, Shaoyou, Fan, Li, Yin, Tinggui, Du, Jian, Beckmann, Richard, Mader, Mary, Zhu, Guoxin, Toth, John, Blanchard, Kerry, Ye, Xiang S.

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Discovery and evaluation of novel SHIP-1 inhibitors von Miao, Jinmin, Lin, Jianping, Dong, Jiajun, Amarasinghe, Ovini, Mason, Emily R., Chu, Shaoyou, Qu, Zihan, Cullers, Clayton C., Putt, Karson S., Zhang, Zhong-Yin

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