Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains von Kwon, Ilmin, Kato, Masato, Xiang, Siheng, Wu, Leeju, Theodoropoulos, Pano, Mirzaei, Hamid, Han, Tina, Xie, Shanhai, Corden, Jeffry L., McKnight, Steven L.

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Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies von Han, Tina W., Kato, Masato, Xie, Shanhai, Wu, Leeju C., Mirzaei, Hamid, Pei, Jimin, Chen, Min, Xie, Yang, Allen, Jeffrey, Xiao, Guanghua, McKnight, Steven L.

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Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels von Kato, Masato, Han, Tina W., Xie, Shanhai, Shi, Kevin, Du, Xinlin, Wu, Leeju C., Mirzaei, Hamid, Goldsmith, Elizabeth J., Longgood, Jamie, Pei, Jimin, Grishin, Nick V., Frantz, Douglas E., Schneider, Jay W., Chen, She, Li, Lin, Sawaya, Michael R., Eisenberg, David, Tycko, Robert, McKnight, Steven L.

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Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS von Lee, Jaeick, Xu, Yingda, Chen, Yue, Sprung, Robert, Kim, Sung Chan, Xie, Shanhai, Zhao, Yingming

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Lead change of a HIF-2α antagonist guided by multiparameter optimization and utilization of an Olp→πAr interaction von Wehn, Paul M., Yang, Song, Grina, Jonas A., Rizzi, James P., Schlachter, Stephen T., Wang, Bin, Xu, Rui, Yang, Hanbiao, Du, Xinlin, Han, Guangzhou, Wang, Keshi, Czerwinski, Robert M., Ged, Emily L., Huang, Heli, Halfmann, Megan M., Maddie, Melissa A., Morton, Emily R., Olive, Sarah R., Tan, Huiling, Xie, Shanhai, Josey, John A., Wallace, Eli M.

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Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains von Kwon, Ilmin, Kato, Masato, Xiang, Siheng, Wu, Leeju, Theodoropoulos, Pano, Mirzaei, Hamid, Han, Tina, Xie, Shanhai, Corden, Jeffry L., McKnight, Steven L.

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Bcr-Abl-mediated suppression of normal hematopoiesis in leukemia von Lin, Hui, Monaco, Giuseppe, Sun, Tong, Ling, Xiaoyang, Stephens, Clifton, Xie, Shanhai, Belmont, John, Arlinghaus, Ralph

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3‑[(1S,2S,3R)‑2,3-Difluoro-1-hydroxy-7-methylsulfonyl­indan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell... von Xu, Rui, Wang, Keshi, Rizzi, James P, Huang, Heli, Grina, Jonas A, Schlachter, Stephen T, Wang, Bin, Wehn, Paul M, Yang, Hanbiao, Dixon, Darryl D, Czerwinski, Robert M, Du, Xinlin, Ged, Emily L, Han, Guangzhou, Tan, Huiling, Wong, Tai, Xie, Shanhai, Josey, John A, Wallace, Eli M

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A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma von Wallace, Eli M, Rizzi, James P, Han, Guangzhou, Wehn, Paul M, Cao, Zhaodan, Du, Xinlin, Cheng, Tzuling, Czerwinski, Robert M, Dixon, Darryl D, Goggin, Barry S, Grina, Jonas A, Halfmann, Megan M, Maddie, Melissa A, Olive, Sarah R, Schlachter, Stephen T, Tan, Huiling, Wang, Bin, Wang, Keshi, Xie, Shanhai, Xu, Rui, Yang, Hanbiao, Josey, John A

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Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3 von Tao, Ye, Budhipramono, Albert, Huang, Ji, Fang, Min, Xie, Shanhai, Kim, Jiwoong, Khivansara, Vishal, Dominski, Zbigniew, Tong, Liang, De Brabander, Jef K., Nijhawan, Deepak

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Jak2 is involved in c-Myc induction by Bcr-Abl von Xie, Shanhai, Lin, Hui, Sun, Tong, Arlinghaus, Ralph B

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Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension von Macias, David, Moore, Stephen, Crosby, Alexi, Southwood, Mark, Du, Xinlin, Tan, Huiling, Xie, Shanhai, Vassallo, Arlette, Wood, Alexander J T, Wallace, Eli M, Cowburn, Andrew S

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Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)‑3-((2,2-Di... von Wehn, Paul M, Rizzi, James P, Dixon, Darryl D, Grina, Jonas A, Schlachter, Stephen T, Wang, Bin, Xu, Rui, Yang, Hanbiao, Du, Xinlin, Han, Guangzhou, Wang, Keshi, Cao, Zhaodan, Cheng, Tzuling, Czerwinski, Robert M, Goggin, Barry S, Huang, Heli, Halfmann, Megan M, Maddie, Melissa A, Morton, Emily L, Olive, Sarah R, Tan, Huiling, Xie, Shanhai, Wong, Tai, Josey, John A, Wallace, Eli M

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Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-D... von Wehn, Paul M, Rizzi, James P, Dixon, Darryl D, Grina, Jonas A, Schlachter, Stephen T, Wang, Bin, Xu, Rui, Yang, Hanbiao, Du, Xinlin, Han, Guangzhou, Wang, Keshi, Cao, Zhaodan, Cheng, Tzuling, Czerwinski, Robert M, Goggin, Barry S, Huang, Heli, Halfmann, Megan M, Maddie, Melissa A, Morton, Emily L, Olive, Sarah R, Tan, Huiling, Xie, Shanhai, Wong, Tai, Josey, John A, Wallace, Eli M

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Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells von XIE, S, PRICE, J. E, LUCA, M, JEAN, D, RONAI, Z, BAR-ELI, M

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Discovery of a Proneurogenic, Neuroprotective Chemical von Pieper, Andrew A., Xie, Shanhai, Capota, Emanuela, Estill, Sandi Jo, Zhong, Jeannie, Long, Jeffrey M., Becker, Ginger L., Huntington, Paula, Goldman, Shauna E., Shen, Ching-Han, Capota, Maria, Britt, Jeremiah K., Kotti, Tiina, Ure, Kerstin, Brat, Daniel J., Williams, Noelle S., MacMillan, Karen S., Naidoo, Jacinth, Melito, Lisa, Hsieh, Jenny, De Brabander, Jef, Ready, Joseph M., McKnight, Steven L.

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Involvement of Jak2 tyrosine phosphorylation in Bcr - Abl transformation von XIE, Shanhai, WANG, Yan, LIU, Jiaxin, SUN, Tong, WILSON, Matthew B, SMITHGALL, Thomas E, ARLINGHAUS, Ralph B

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Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules von Nguyen, Thu P., Fang, Min, Kim, Jiwoong, Wang, Baiyun, Lin, Elisa, Khivansara, Vishal, Barrows, Neha, Rivera-Cancel, Giomar, Goralski, Maria, Cervantes, Christopher L., Xie, Shanhai, Peterson, Johann M., Povedano, Juan Manuel, Antczak, Monika I., Posner, Bruce A., Harvey, Colin J.B., Naughton, Brian T., McFadden, David G., Ready, Joseph M., De Brabander, Jef K., Nijhawan, Deepak

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Bcr-Abl-mediated suppression of normal hematopoiesis in leukemia von HUI LIN, MONACO, Giuseppe, TONG SUN, XIAOYANG LING, STEPHENS, Clifton, SHANHAI XIE, BELMONT, John, ARLINGHAUS, Ralph

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Abstract 4022: PT2385, a novel HIF-2 antagonist, combines with checkpoint inhibitor antibodies to inhibit tumor growth in preclinical models by modulating myeloid cells and enhanci... von Han, Guangzhou, Stevens, Christina, Cao, Zhaodan, Xie, Shanhai, Maddie, Melissa, Goggin, Barry, Wallace, Eli, Josey, John, Wong, Tai W

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