An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer von MCCLELAND, Mark L, ADLER, Adam S, BELVIN, Marcia, HATZIVASSILIOU, Georgia, BLACKWOOD, Elizabeth M, CORSON, Laura, EVANGELISTA, Marie, JIPING ZHA, FIRESTEIN, Ron, YONGLEI SHANG, HUNSAKER, Thomas, TRUONG, Tom, PETERSON, David, TORRES, Eric, LI LI, HALEY, Benjamin, STEPHAN, Jean-Philippe

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Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining von Hsiao, Yi-Chun, Wallweber, Heidi Ackerly, Alberstein, Robert G., Lin, Zhonghua, Du, Changchun, Etxeberria, Ainhoa, Aung, Theint, Shang, Yonglei, Seshasayee, Dhaya, Seeger, Franziska, Watkins, Andrew M., Hansen, David V., Bohlen, Christopher J., Hsu, Peter L., Hötzel, Isidro

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Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics von Bumbaca Yadav, Daniela, Sharma, Vikas K., Boswell, Charles Andrew, Hotzel, Isidro, Tesar, Devin, Shang, Yonglei, Ying, Yong, Fischer, Saloumeh K., Grogan, Jane L., Chiang, Eugene Y., Urban, Konnie, Ulufatu, Sheila, Khawli, Leslie A., Prabhu, Saileta, Joseph, Sean, Kelley, Robert F.

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The mitochondrial inner membrane protein mitofilin controls cristae morphology von John, George B, Shang, Yonglei, Li, Li, Renken, Christian, Mannella, Carmen A, Selker, Jeanne M L, Rangell, Linda, Bennett, Michael J, Zha, Jiping

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A high throughput bispecific antibody discovery pipeline von Segaliny, Aude I., Jayaraman, Jayapriya, Chen, Xiaoming, Chong, Jonathan, Luxon, Ryan, Fung, Audrey, Fu, Qiwei, Jiang, Xianzhi, Rivera, Rodrigo, Ma, Xiaoya, Ren, Ci, Zimak, Jan, Hedde, Per Niklas, Shang, Yonglei, Wu, George, Zhao, Weian

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Corrigendum to “Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mo... von Sengupta-Ghosh, Arundhati, Dominguez, Sara L., Xie, Luke, Barck, Kai H., Jiang, Zhiyu, Earr, Timothy, Imperio, Jose, Phu, Lilian, Budayeva, Hanna G., Kirkpatrick, Donald S., Cai, Hao, He, Dongping, Eastham-Anderson, Jeffrey, Ngu, Hai, Foreman, Oded, Hedehus, Maj, Reichelt, Michael, Hotzel, Isidro, Shang, Yonglei, Carano, Richard A.D., Ayalon, Gai, Easton, Amy

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Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS von Sengupta-Ghosh, Arundhati, Dominguez, Sara L., Xie, Luke, Barck, Kai H., Jiang, Zhiyu, Earr, Timothy, Imperio, Jose, Phu, Lilian, Budayeva, Hanna G., Kirkpatrick, Donald S., Cai, Hao, Eastham-Anderson, Jeffrey, Ngu, Hai, Foreman, Oded, Hedehus, Maj, Reichelt, Michael, Hotzel, Isidro, Shang, Yonglei, Carano, Richard A.D., Ayalon, Gai, Easton, Amy

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Polyubiquitination of Insulin-like Growth Factor I Receptor (IGF-IR) Activation Loop Promotes Antibody-induced Receptor Internalization and Down-regulation von Mao, Yifan, Shang, Yonglei, Pham, Victoria C., Ernst, James A., Lill, Jennie R., Scales, Suzie J., Zha, Jiping

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Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake von Shang, Yonglei, Mao, Yifan, Batson, Jennifer, Scales, Suzie J, Phillips, Gail, Lackner, Mark R, Totpal, Klara, Williams, Simon, Yang, Jihong, Tang, Zhijun, Modrusan, Zora, Tan, Christine, Liang, Wei-Ching, Tsai, Siao Ping, Vanderbilt, Alexander, Kozuka, Kenji, Hoeflich, Klaus, Tien, Janet, Ross, Sarajane, Li, Congfen, Lee, Sang Hoon, Song, An, Wu, Yan, Stephan, Jean-Philippe, Ashkenazi, Avi, Zha, Jiping

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mRNA rescues neonatal acidemia while mice report no aftereffects von Zimak, Jan, Shang, Yonglei, Zhao, Weian

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Barcoded sequencing workflow for high throughput digitization of hybridoma antibody variable domain sequences von Chen, Yongmei, Kim, Si Hyun, Shang, Yonglei, Guillory, Joseph, Stinson, Jeremy, Zhang, Qing, Hötzel, Isidro, Hoi, Kam Hon

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Modular protein expression by RNA trans-splicing enables flexible expression of antibody formats in mammalian cells from a dual-host phage display vector von Shang, Yonglei, Tesar, Devin, Hötzel, Isidro

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Immune repertoire mining for rapid affinity optimization of mouse monoclonal antibodies von Hsiao, Yi-Chun, Shang, Yonglei, DiCara, Danielle M, Yee, Angie, Lai, Joyce, Kim, Si Hyun, Ellerman, Diego, Corpuz, Racquel, Chen, Yongmei, Rajan, Sharmila, Cai, Hao, Wu, Yan, Seshasayee, Dhaya, Hötzel, Isidro

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Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor von Mukund, Susmith, Shang, Yonglei, Clarke, Holly J., Madjidi, Azadeh, Corn, Jacob E., Kates, Lance, Kolumam, Ganesh, Chiang, Vicky, Luis, Elizabeth, Murray, Jeremy, Zhang, Yingnan, Hötzel, Isidro, Koth, Christopher M., Allan, Bernard B.

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Polypeptide expression systems von Shang, Yonglei, Hotzel, Isidro

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Depletion of major pathogenic cells in asthma by targeting CRTh2 von Huang, Tao, Hazen, Meredith, Shang, Yonglei, Zhou, Meijuan, Wu, Xiumin, Yan, Donghong, Lin, Zhonghua, Solon, Margaret, Luis, Elizabeth, Ngu, Hai, Shi, Yongchang, Katewa, Arna, Choy, David F, Ramamoorthi, Nandhini, Castellanos, Erick R, Balazs, Mercedesz, Xu, Min, Lee, Wyne P, Matsumoto, Marissa L, Payandeh, Jian, Arron, Joseph R, Hongo, Jo-Anne, Wang, Jianyong, Hötzel, Isidro, Austin, Cary D, Reif, Karin

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COMPARTMENTALIZED ASSAYS OF BISPECIFIC AND MULTISPECIFIC BIOLOGICS von Shang, Yonglei, Wu, George Guikai

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Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1 G93A mouse model of AL... von Sengupta-Ghosh, Arundhati, Dominguez, Sara L, Xie, Luke, Barck, Kai H, Jiang, Zhiyu, Earr, Timothy, Imperio, Jose, Phu, Lilian, Budayeva, Hanna G, Kirkpatrick, Donald S, Cai, Hao, Eastham-Anderson, Jeffrey, Ngu, Hai, Foreman, Oded, Hedehus, Maj, Reichelt, Michael, Hotzel, Isidro, Shang, Yonglei, Carano, Richard A D, Ayalon, Gai, Easton, Amy

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Compartmentalized assays of bispecific and multispecific biologics von Shang, Yonglei, Wu, George Guikai

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POLYPEPTIDE EXPRESSION SYSTEMS von SHANG, Yonglei, HOTZEL, Isidro

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