Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives von Amporndanai, Kangsa, Meng, Xiaoli, Shang, Weijuan, Jin, Zhenmig, Rogers, Michael, Zhao, Yao, Rao, Zihe, Liu, Zhi-Jie, Yang, Haitao, Zhang, Leike, O’Neill, Paul M., Samar Hasnain, S.

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Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease von Su, Haixia, Yao, Sheng, Zhao, Wenfeng, Zhang, Yumin, Liu, Jia, Shao, Qiang, Wang, Qingxing, Li, Minjun, Xie, Hang, Shang, Weijuan, Ke, Changqiang, Feng, Lu, Jiang, Xiangrui, Shen, Jingshan, Xiao, Gengfu, Jiang, Hualiang, Zhang, Leike, Ye, Yang, Xu, Yechun

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High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors von Zhao, Yao, Du, Xiaoyu, Duan, Yinkai, Pan, Xiaoyan, Sun, Yifang, You, Tian, Han, Lin, Jin, Zhenming, Shang, Weijuan, Yu, Jing, Guo, Hangtian, Liu, Qianying, Wu, Yan, Peng, Chao, Wang, Jun, Zhu, Chenghao, Yang, Xiuna, Yang, Kailin, Lei, Ying, Guddat, Luke W., Xu, Wenqing, Xiao, Gengfu, Sun, Lei, Zhang, Leike, Rao, Zihe, Yang, Haitao

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Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 von Xie, Yuanchao, Yin, Wanchao, Zhang, Yumin, Shang, Weijuan, Wang, Zhen, Luan, Xiaodong, Tian, Guanghui, Aisa, Haji A., Xu, Yechun, Xiao, Gengfu, Li, Jia, Jiang, Hualiang, Zhang, Shuyang, Zhang, Leike, Xu, H. Eric, Shen, Jingshan

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Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir von Jiang, Xiangrui, Su, Haixia, Shang, Weijuan, Zhou, Feng, Zhang, Yan, Zhao, Wenfeng, Zhang, Qiumeng, Xie, Hang, Jiang, Lei, Nie, Tianqing, Yang, Feipu, Xiong, Muya, Huang, Xiaoxing, Li, Minjun, Chen, Ping, Peng, Shaoping, Xiao, Gengfu, Jiang, Hualiang, Tang, Renhong, Zhang, Leike, Shen, Jingshan, Xu, Yechun

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Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 von Xiong, Rui, Zhang, Leike, Li, Shiliang, Sun, Yuan, Ding, Minyi, Wang, Yong, Zhao, Yongliang, Wu, Yan, Shang, Weijuan, Jiang, Xiaming, Shan, Jiwei, Shen, Zihao, Tong, Yi, Xu, Liuxin, Chen, Yu, Liu, Yingle, Zou, Gang, Lavillete, Dimitri, Zhao, Zhenjiang, Wang, Rui, Zhu, Lili, Xiao, Gengfu, Lan, Ke, Li, Honglin, Xu, Ke

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Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model von Zhang, Ruxue, Zhang, Yumin, Zheng, Wei, Shang, Weijuan, Wu, Yan, Li, Ning, Xiong, Jun, Jiang, Hualiang, Shen, Jingshan, Xiao, Gengfu, Xie, Yuanchao, Zhang, Leike

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A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein von Li, Yang, Shang, Weijuan, Xiao, Gengfu, Zhang, Lei-Ke, Zheng, Congyi

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A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells von Wan, Weiwei, Wang, Liangjie, Chen, Xi, Zhu, Shenglin, Shang, Weijuan, Xiao, Gengfu, Zhang, Lei-Ke

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Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses von Lu, Shengsheng, Pan, Xiaoyan, Chen, Daiwei, Xie, Xi, Wu, Yan, Shang, Weijuan, Jiang, Xiaming, Sun, Yuan, Fan, Sheng, He, Jian

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A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir von Zhang, Yumin, Sun, Yuan, Xie, Yuanchao, Shang, Weijuan, Wang, Zhen, Jiang, Hualiang, Shen, Jingshan, Xiao, Gengfu, Zhang, Leike

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RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates von Pan, Xiaoyan, Shi, Jian, Hu, Xue, Wu, Yan, Zeng, Liang, Yao, Yanfeng, Shang, Weijuan, Liu, Kunpeng, Gao, Ge, Guo, Weiwei, Peng, Yun, Chen, Shaohong, Gao, Xiaoxiao, Peng, Cheng, Rao, Juhong, Zhao, Jiaxuan, Gong, Cheng, Zhou, Hui, Lu, Yudong, Wang, Zili, Hu, Xiliang, Cong, WenJuan, Fang, Lijuan, Yan, Yongxiang, Zhang, Jing, Xiong, Hui, Yi, Jizu, Yuan, Zhiming, Zhou, Pengfei, Shan, Chao, Xiao, Gengfu

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Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus von Wang, Qingxing, Xin, Qilin, Shang, Weijuan, Wan, Weiwei, Xiao, Gengfu, Zhang, Lei-Ke

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Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro von Zhang, Leike, Liu, Jia, Cao, Ruiyuan, Xu, Mingyue, Wu, Yan, Shang, Weijuan, Wang, Xi, Zhang, Huanyu, Jiang, Xiaming, Sun, Yuan, Hu, Hengrui, Li, Yufeng, Zou, Gang, Zhang, Min, Zhao, Lei, Li, Wei, Guo, Xiaojia, Zhuang, Xiaomei, Yang, Xing-Lou, Shi, Zheng-Li, Deng, Fei, Hu, Zhihong, Xiao, Gengfu, Wang, Manli, Zhong, Wu

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Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 von Xiong, Rui, Zhang, Leike, Li, Shiliang, Sun, Yuan, Ding, Minyi, Wang, Yong, Zhao, Yongliang, Wu, Yan, Shang, Weijuan, Jiang, Xiaming, Shan, Jiwei, Shen, Zihao, Tong, Yi, Xu, Liuxin, Chen, Yu, Liu, Yingle, Zou, Gang, Lavillete, Dimitri, Zhao, Zhenjiang, Wang, Rui, Zhu, Lili, Xiao, Gengfu, Lan, Ke, Li, Honglin, Xu, Ke

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Visualizing lymphocytic choriomeningitis virus infection in cells and living mice von Wen, Yuxi, Xu, Huan, Wan, Weiwei, Shang, Weijuan, Jin, Runming, Zhou, Fen, Mei, Heng, Wang, Jingshi, Xiao, Gengfu, Chen, Hongbo, Wu, Xiaoyan, Zhang, Leike

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Peptidomimetic Analogues Act as Effective Inhibitors against SARS-CoV‑2 by Blocking the Function of Cathepsin L von Deng, Weilong, Hu, Xiao, Tian, Xiaoman, Zhang, Yuanyuan, Shang, Weijuan, Zhang, Leike, Shang, Luqing

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Probing the Allosteric Inhibition Mechanism of a Spike Protein Using Molecular Dynamics Simulations and Active Compound Identifications von Wang, Qian, Wang, Lin, Zhang, Yumin, Zhang, XiangLei, Zhang, Leike, Shang, Weijuan, Bai, Fang

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In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2 von Shang, Weijuan, Dai, Wenhao, Yao, Cheng, Xu, Ling, Tao, Xiangming, Su, Haixia, Li, Jian, Xie, Xiong, Xu, Yechun, Hu, Min, Xie, Dong, Jiang, Hualiang, Zhang, Leike, Liu, Hong

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Immunoglobulin fragment F(ab’)2 against RBD potently neutralizes SARS-CoV-2 in vitro von Pan, Xiaoyan, Zhou, Pengfei, Fan, Tiejiong, Wu, Yan, Zhang, Jing, Shi, Xiaoyue, Shang, Weijuan, Fang, Lijuan, Jiang, Xiaming, Shi, Jian, Sun, Yuan, Zhao, Shaojuan, Gong, Rui, Chen, Ze, Xiao, Gengfu

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